Nancy E Cox

US Patent:

8241853, Aug 14, 2012

Filed:

Aug 13, 2008

Appl. No.:

12/191186

Inventors:

Stephen Lindstrom - Doraville GA, US
Alexander Klimov - Atlanta GA, US
Nancy Cox - Atlanta GA, US
Lamorris Loftin - Philadelphia PA, US

Assignee:

The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention - Washington DC

International Classification:

C12Q 1/68
C12M 1/34
C07H 21/04

US Classification:

435 611, 435 5, 435 61, 435 612, 4352872, 435810, 536 2432, 536 2433

Abstract:

Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.

US Patent:

8568981, Oct 29, 2013

Filed:

Jul 20, 2012

Appl. No.:

13/554782

Inventors:

Stephen Lindstrom - Doraville GA, US
Alexander Klimov - Atlanta GA, US
Nancy Cox - Atlanta GA, US
Lamorris Loftin - Philadelphia PA, US

Assignee:

The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention - Washington DC

International Classification:

C12Q 1/68
C07H 21/04
C12M 1/34

US Classification:

435 611, 435 612, 4352872, 435810, 536 2432, 536 2433

Abstract:

Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.

US Patent:

20190314488, Oct 17, 2019

Filed:

Apr 12, 2019

Appl. No.:

16/382429

Inventors:

- Gainesville FL, US
- Ithaca NY, US
- Atlanta GA, US
RUBEN OMAR DONIS - ATLANTA GA, US
JACQUELINE KATZ - ATLANTA GA, US
ALEXANDER I. KLIMOV - ATLANTA GA, US
NALLAKANNU P. LAKSHMANAN - MILLSBORO DE, US
MELISSA ANNE LUM - MILLSBORO DE, US
DANIEL GHISLENA EMIEL GOOVAERTS - BOXMEER, NL
MARK WILLIAM MELLENCAMP - DESOTO KS, US
NANCY J. COX - ATLANTA GA, US
WILLIAM L. CASTLEMAN - GAINESVILLE FL, US

International Classification:

A61K 39/145
C12N 15/86
A61K 39/12
C07K 14/005
C07K 16/10
C12N 7/00
C12Q 1/70
G01N 33/569

Abstract:

The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and methods for inducing an immune response against an influenza virus of the present invention. The subject invention also pertains to compositions and methods for identifying a virus of the invention and diagnosing infection of an animal with a virus of the invention.

US Patent:

20180169217, Jun 21, 2018

Filed:

Feb 5, 2018

Appl. No.:

15/888715

Inventors:

- GAINESVILLE FL, US
- Ithaca NY, US
- Atlanta GA, US
RUBEN OMAR DONIS - ATLANTA GA, US
JACQUELINE KATZ - ATLANTA GA, US
ALEXANDER I. KLIMOV - ATLANTA GA, US
NALLAKANNU P. LAKSHMANAN - MILLSBORO DE, US
MELISSA ANNE LUM - MILLSBORO DE, US
DANIEL GHISLENA EMIEL GOOVAERTS - BOXMEER, NL
MARK WILLIAM MELLENCAMP - DESOTO KS, US
NANCY J. COX - ATLANTA GA, US
WILLIAM L. CASTLEMAN - GAINESVILLE FL, US

International Classification:

A61K 39/145
A61K 39/12
C07K 14/005
C07K 16/10
C12N 7/00
C12N 15/86
C12Q 1/70
G01N 33/569

Abstract:

The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and methods for inducing an immune response against an influenza virus of the present invention. The subject invention also pertains to compositions and methods for identifying a virus of the invention and diagnosing infection of an animal with a virus of the invention.

US Patent:

20160289777, Oct 6, 2016

Filed:

Jun 15, 2016

Appl. No.:

15/182852

Inventors:

- Bethesda MD, US
Alexander Klimov - , US
Nancy Cox - Atlanta GA, US
Lamorris Loftin - Philadelphia PA, US

Assignee:

The Government of the U.S.A. as represented by the Secretary of the Dept. of Health and Human Servic - Bethesda MD

International Classification:

C12Q 1/70

Abstract:

Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.

US Patent:

20150056235, Feb 26, 2015

Filed:

Oct 6, 2014

Appl. No.:

14/507332

Inventors:

- GAINESVILLE FL, US
- ITHACA NY, US
- ATLANTA GA, US
RUBEN OMAR DONIS - ATLANTA GA, US
JACQUELINE KATZ - ATLANTA GA, US
ALEXANDER I. KLIMOV - ATLANTA GA, US
NALLAKANNU P. LAKSHMANAN - MILLSBORO DE, US
MELISSA ANNE LUM - MILLSBORO DE, US
DANIEL GHISLENA EMIEL GOOVAERTS - BOXMEER, NL
MARK WILLIAM MELLENCAMP - DESOTO KS, US
NANCY J. COX - ATLANTA GA, US
WILLIAM L. CASTLEMAN - GAINESVILLE FL, US

International Classification:

A61K 39/145
C12N 15/86
C07K 16/10
C12N 7/00

US Classification:

4241861, 4242091, 4242061, 4241991, 4352351, 4353201, 435236

Abstract:

The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and methods for inducing an immune response against an influenza virus of the present invention. The subject invention also pertains to compositions and methods for identifying a virus of the invention and diagnosing infection of an animal with a virus of the invention.

US Patent:

20140128279, May 8, 2014

Filed:

Oct 17, 2013

Appl. No.:

14/056810

Inventors:

- Atlanta GA, US
Alexander Klimov - , US
Nancy Cox - Atlanta GA, US
Lamorris Loftin - Philadelphia PA, US

Assignee:

The Government of the United States of America as represented by the Secretary of the Department of - Atlanta GA

International Classification:

C12Q 1/70

US Classification:

506 9, 536 2432, 536 2433, 435 5, 506 16

Abstract:

Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.