Nancy B Cox

US Patent:

7959929, Jun 14, 2011

Filed:

Oct 19, 2006

Appl. No.:

11/584818

Inventors:

Patti C. Crawford - Gainesville FL, US
Paul J. Gibbs - Gainesville FL, US
Edward J. Dubovi - Ithaca NY, US
Ruben Omar Donis - Atlanta GA, US
Jacqueline Katz - Atlanta GA, US
Alexander I. Klimov - Atlanta GA, US
Nallakannu P. Lakshmanan - Millsboro DE, US
Melissa Anne Lum - Millsboro DE, US
Daniel Ghislena Emiel Goovaerts - The Netherlands, BE
Mark William Mellencamp - Desoto KS, US
Nancy J. Cox - Atlanta GA, US
William L. Castleman - Gainesville FL, US

Assignee:

University of Florida Research Foundation, Inc. - Gainesville FL
Cornell Research Foundation, Inc. - Ithaca NY
The United States of America as represented by the Secretary of the Department of Health and Human Services - Washington DC
Centers for Disease Control and Prevention - Atlanta GA
Intervet International B.V.

International Classification:

A61K 49/00
A61K 39/00
A61K 39/12
A61K 39/145
A61K 45/00
C12Q 1/70
C12N 7/00
C12N 7/04
C07K 14/00
C07K 16/00
A61K 39/285

US Classification:

4242061, 424 91, 4241841, 4241851, 4241861, 4242041, 4242051, 4242091, 4242811, 435 5, 4352351, 435236, 530350, 530396

Abstract:

The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and methods for inducing an immune response against an influenza virus of the present invention. The subject invention also pertains to compositions and methods for identifying a virus of the invention and diagnosing infection of an animal with a virus of the invention.

US Patent:

8241853, Aug 14, 2012

Filed:

Aug 13, 2008

Appl. No.:

12/191186

Inventors:

Stephen Lindstrom - Doraville GA, US
Alexander Klimov - Atlanta GA, US
Nancy Cox - Atlanta GA, US
Lamorris Loftin - Philadelphia PA, US

Assignee:

The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention - Washington DC

International Classification:

C12Q 1/68
C12M 1/34
C07H 21/04

US Classification:

435 611, 435 5, 435 61, 435 612, 4352872, 435810, 536 2432, 536 2433

Abstract:

Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.

US Patent:

8568981, Oct 29, 2013

Filed:

Jul 20, 2012

Appl. No.:

13/554782

Inventors:

Stephen Lindstrom - Doraville GA, US
Alexander Klimov - Atlanta GA, US
Nancy Cox - Atlanta GA, US
Lamorris Loftin - Philadelphia PA, US

Assignee:

The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention - Washington DC

International Classification:

C12Q 1/68
C07H 21/04
C12M 1/34

US Classification:

435 611, 435 612, 4352872, 435810, 536 2432, 536 2433

Abstract:

Methods of detecting influenza, including differentiating between type and subtype are disclosed, for example to detect, type, and/or subtype an influenza infection. A sample suspected of containing a nucleic acid of an influenza virus, is screened for the presence or absence of that nucleic acid. The presence of the influenza virus nucleic acid indicates the presence of influenza virus. Determining whether the influenza virus nucleic acid is present in the sample can be accomplished by detecting hybridization between an influenza specific probe, influenza type specific probe, and/or subtype specific probe and an influenza nucleic acid. Probes and primers for the detection, typing and/or subtyping of influenza virus are also disclosed. Kits and arrays that contain the disclosed probes and/or primers also are disclosed.

US Patent:

20090124512, May 14, 2009

Filed:

Jan 18, 2007

Appl. No.:

12/160784

Inventors:

Kathy L. Rowlen - Boulder CO, US
Robert Kuchta - Boulder CO, US
Michael Townsend - Atlanta GA, US
James Smagala - Arvada CO, US
Chad L. Moore - San Diego CA, US
Erica Dawson - Broomfield CO, US
Martin Mehlmann - Birsfelden, CH
Nancy Cox - Atlanta GA, US
Catherine B. Smith - Stone Mountain GA, US
Daniela Mehlmann - Birsfelden, CH

Assignee:

REGENTS OF THE UNIVERSITY OF COLORADO - Denver CO

International Classification:

C40B 40/06
C40B 50/00
C40B 30/04

US Classification:

506 9, 506 16, 506 23

Abstract:

Embodiments herein provide for methods, compositions and apparati for detection and/or diagnosis of virus types, subtypes and/or strains. In particular embodiments, the virus is an influenza virus. The apparatus may include a microarray with attached capture probes, designed to bind to oligonucleotides capable of binding at least a portion of a nucleic acid sequence of one or more target genes in a broad array of influenza types, subtypes or strains. The compositions may include isolated nucleic acids as capture probes, target sequences and/or tagged label probes, of use for diagnosis and/or detection of influenza virus.

US Patent:

20100130378, May 27, 2010

Filed:

Jan 3, 2008

Appl. No.:

12/522146

Inventors:

Kathy L. Rowlen - Boulder CO, US
Daniela M. Mehlmann - Birsfelden, CH
Robert Kuchta - Boulder CO, US
Martin Mehlmann - Birsfelden, CH
James Smagala - Arvada CO, US
Chad Moore - San Diego CA, US
Nancy Cox - Atlanta GA, US
Michael W. Shaw - Decatur GA, US

International Classification:

C40B 30/04
C40B 40/06
C40B 50/14

US Classification:

506 9, 506 16, 506 30

Abstract:

Embodiments herein provide for methods, compositions and apparatus for detection and/or diagnosis of pathogenic virus lineage and/or strains. In some embodiments, the virus is influenza Type B virus. In other embodiments, an apparatus may include a microarray with attached capture probes, designed to bind to nucleic acid sequences from a single gene in a broad array of influenza strains. In some embodiments, compositions may include isolated nucleic acid sequences of use as capture probes, target sequences and/or label probe sequences, for diagnosis of and/or detection of influenza virus.

US Patent:

20110311586, Dec 22, 2011

Filed:

Apr 19, 2011

Appl. No.:

13/066651

Inventors:

Patti C. Crawford - Gainesville FL, US
Paul J. Gibbs - Gainesville FL, US
Edward J. Dubovi - Ithaca NY, US
Ruben Omar Donis - Atlanta GA, US
Jacqueline Katz - Atlanta GA, US
Alexander I. Klimov - Atlanta GA, US
Nallakannu P. Lakshmanan - Millsboro DE, US
Melissa Anne Lum - Millsboro DE, US
Daniel Ghislena Emiel Goovaerts - Boxmeer, NL
Mark William Mellencamp - Desoto KS, US
William L. Castleman - Gainesville FL, US
Nancy J. Cox - Atlanta GA, US

Assignee:

University of Florida Research Foundation, Inc. - Gainesville FL
Intervet International B.V. - Boxmeer
The Govt. of the U.S.A. as represented by The Secretary of the Dept. of Health & Human Services - Atlanta GA
Cornell Research Foundation, Inc. - Ithaca NY

International Classification:

A61K 39/145
C12N 7/04
C07H 21/00
A61P 31/16
C12N 9/12
C12N 9/24
A61P 37/04
C12N 7/00
C07K 14/11

US Classification:

4242101, 4352351, 435236, 4242091, 536 2372, 536 232, 530358, 530350, 435194, 435200

Abstract:

The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and methods for inducing an immune response against an influenza virus of the present invention. The subject invention also pertains to compositions and methods for identifying a virus of the invention and diagnosing infection of an animal with a virus of the invention.

US Patent:

20190314488, Oct 17, 2019

Filed:

Apr 12, 2019

Appl. No.:

16/382429

Inventors:

- Gainesville FL, US
- Ithaca NY, US
- Atlanta GA, US
RUBEN OMAR DONIS - ATLANTA GA, US
JACQUELINE KATZ - ATLANTA GA, US
ALEXANDER I. KLIMOV - ATLANTA GA, US
NALLAKANNU P. LAKSHMANAN - MILLSBORO DE, US
MELISSA ANNE LUM - MILLSBORO DE, US
DANIEL GHISLENA EMIEL GOOVAERTS - BOXMEER, NL
MARK WILLIAM MELLENCAMP - DESOTO KS, US
NANCY J. COX - ATLANTA GA, US
WILLIAM L. CASTLEMAN - GAINESVILLE FL, US

International Classification:

A61K 39/145
C12N 15/86
A61K 39/12
C07K 14/005
C07K 16/10
C12N 7/00
C12Q 1/70
G01N 33/569

Abstract:

The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and methods for inducing an immune response against an influenza virus of the present invention. The subject invention also pertains to compositions and methods for identifying a virus of the invention and diagnosing infection of an animal with a virus of the invention.

US Patent:

20180169217, Jun 21, 2018

Filed:

Feb 5, 2018

Appl. No.:

15/888715

Inventors:

- GAINESVILLE FL, US
- Ithaca NY, US
- Atlanta GA, US
RUBEN OMAR DONIS - ATLANTA GA, US
JACQUELINE KATZ - ATLANTA GA, US
ALEXANDER I. KLIMOV - ATLANTA GA, US
NALLAKANNU P. LAKSHMANAN - MILLSBORO DE, US
MELISSA ANNE LUM - MILLSBORO DE, US
DANIEL GHISLENA EMIEL GOOVAERTS - BOXMEER, NL
MARK WILLIAM MELLENCAMP - DESOTO KS, US
NANCY J. COX - ATLANTA GA, US
WILLIAM L. CASTLEMAN - GAINESVILLE FL, US

International Classification:

A61K 39/145
A61K 39/12
C07K 14/005
C07K 16/10
C12N 7/00
C12N 15/86
C12Q 1/70
G01N 33/569

Abstract:

The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and methods for inducing an immune response against an influenza virus of the present invention. The subject invention also pertains to compositions and methods for identifying a virus of the invention and diagnosing infection of an animal with a virus of the invention.

Address:

7026 Duncans Gln Dr, Knoxville, TN 37919

Phone:

8657660080

VIN:

5J8TB18577A003352

Make:

ACURA

Model:

RDX

Year:

2007