Kit S. Lam - Oakland CA, US Ruiwu Liu - Oakland CA, US Wei Yao - Oakland CA, US Nancy Lane - Oakland CA, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA
International Classification:
C07K 5/11 A61K 47/48
US Classification:
424 937, 530330, 514 169, 514 167, 514 168
Abstract:
The present invention provides compounds and pharmaceutical compositions of a peptidomimetic ligand, e.g. LLP2A, conjugated with a bisphosphonate drug, e.g. Alendronate. The compounds and pharmaceutical compositions of the present invention are useful in the treatment of osteoporosis and for the promotion of bone growth due to their specificity for the αβintegrin on mesenchymal stem cells and for the surface of bone.
2011 to Jan 2011 Endowed Chair in Aging and Professor of Medicine and RheumatologyCenter for Healthy Aging at UC Davis
2005 to 2011 DirectorUniversity of California
1997 to 2004 Associate Professor of Medicine and Rheumatology, In ResidenceSFGH/UCSF
1992 to 2004 FacultySFGH/UCSF
1990 to 2004 Attending physician, Medicine and RheumatologySFGH/UCSF
1990 to 2004 FacultyHRSA/AIDS Education and Training Centers
1991 to 1998 Rheumatology ConsultantAssociate Clinical Professor of Medicine and Rheumatology, UCSF 1995 to 1997Division of Rheumatology San Francisco, CA 1990 to 1997 FacultyAssistant Clinical Professor of Medicine and Rheumatology, UCSF 1990 to 1995Assistant Voluntary Clinical Professor of Medicine, Rheumatology, Stanford 1988 to 1990Syntex Laboratories
1987 to 1990 Associate Director, Clinical Investigation
Education:
University of California Davis, CA 1976 BS in Biochemistry
Medicine Doctors
Dr. Nancy E Lane, Sacramento CA - MD (Doctor of Medicine)
UC Davis Med Ctr Int Med 4625 2Nd Ave Suite 1002, Sacramento, CA 95817 9167340758 (Phone)
Procedures:
Joint Drainage
Conditions:
Arthritis Degenerative Disc Disease Dermatomyositis Fibromyalgia Low Back Pain Osteoarthritis Osteoarthritis of Hand or Wrist Osteopenia Osteoporosis Patellofemoral Pain Syndrome or Knee Pain Polymyalgia Rheumatica (PMR) Rheumatoid Arthritis Systemic Sclerosis
Certifications:
Internal Medicine, 1983 Rheumatology, 1986
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
UC Davis Med Ctr Int Med 4625 2Nd Ave Suite 1002, Sacramento, CA 95817
UCSF Medical Center 505 Parnassus Avenue, San Francisco, CA 94143
Education:
Medical School University of California At San Francisco Graduated: 1980 Medical School Mt Zion Hosp Graduated: 1980 Medical School Stanford Graduated: 1980
Medical School University of California, San Francisco School of Medicine Graduated: 1980
Conditions:
Osteoarthritis Osteoporosis
Description:
Dr. Lane graduated from the University of California, San Francisco School of Medicine in 1980. She works in Sacramento, CA and specializes in Rheumatology. Dr. Lane is affiliated with UC Davis Medical Center.