Neil A Goldstein

US Patent:

20110039779, Feb 17, 2011

Filed:

Apr 23, 2008

Appl. No.:

12/597482

Inventors:

Soren Ostergaard - Bagsvaerd, DK
Renuta Pillutla - Edison NJ, US
Paul Fletcher - Edison NJ, US
Lauge Schaffer - Bagsvaerd, DK
Stenfeldt Mathiasen - Bagsvaerd, DK
Neil L. Goldstein - Edison NJ, US
Jane Spetzler - Bagsvaerd, DK

International Classification:

A61K 38/16
C07K 14/00
A61P 35/00

US Classification:

514 133, 530324, 514 193

Abstract:

The present invention is drawn to new peptides and proteins that bind to human insulin-like growth factor-1 receptor (HIGF-IR), as well as nucleic acids encoding the same, vectors and cells comprising such nucleic acids, pharmaceutical compositions comprising such compounds, and methods of using any thereof, are provided.

US Patent:

46998802, Oct 13, 1987

Filed:

Sep 25, 1984

Appl. No.:

6/654273

Inventors:

Neil I. Goldstein - New Brunswick NJ

Assignee:

Immunomedics, Inc. - Newark NJ

International Classification:

C12N 500
G01N 33577

US Classification:

4351722

Abstract:

A method for determining the presence of an antigen in a liquid sample. The method includes incubating the sample with an antibody which specifically binds an epitope on the antigen in the presence of a given quantity of an anti-idiotype antibody which specifically binds an epitope on the hypervariable region of the antibody. Also, a method of producing a monoclonal anti-idiotype antibody by fusing lymphocytes from an animal in which a tumor capable of secreting idiotype antibodies has been grown, with myeloma cells.