Neil Mark Richtand

US Patent:

20050009023, Jan 13, 2005

Filed:

Jul 3, 2002

Appl. No.:

10/482503

Inventors:

Neil Richtand - Cincinnati OH, US
Floyd Sallee - Cincinnati OH, US
Danzhao Wang - Norcross, UA

International Classification:

C12Q001/68

US Classification:

435006000

Abstract:

Behavioral sensitization to phsychostimulants involves neuroadaptation of stress-responsive systems. The present invention provides glucocorticoid-induced receptor nucleotides and proteins belonging to G protein-coupled receptor superfamily. The present invention also provides methods methods for determining suscepibility of psychogenic disorders such as depression, anxiety and addiction as well as the development of treatments for central nervous system disorders through glucocorticoid-induced receptor expression modulation.

US Patent:

20040176467, Sep 9, 2004

Filed:

Feb 9, 2004

Appl. No.:

10/486593

Inventors:

Neil Richtand - Cincinnati OH, US

International Classification:

A61K031/137

US Classification:

514/649000

Abstract:

A method of preventing or suppressing symptoms of psychosis by treating non-psychotic patients who are at risk of developing psychosis. The method includes determining whether a patient is at risk for developing psychosis; making a diagnosis that the patient is at risk; and administering to the patient a selective D3 antagonist prior to the time the patient is psychotic in an amount sufficient to prevent or suppress symptoms of psychosis.