David Carroll - Winston-Salem NC, US William Wagner - Clemmons NC, US Nicole Levi - Winston-Salem NC, US Louis Argenta - Winston-Salem NC, US Michael Morykwas - Winston-Salem NC, US
Assignee:
Wake Forest University - Winston-Salem NC Wake Forest University Health Sciences - Winston-Salem NC
International Classification:
A61K 35/12
US Classification:
424 937, 424572, 977904, 977742
Abstract:
A method of carrying out an autologous tissue implant in a subject in need thereof is carried out by: (a) forming an autologous tissue implant from autologous cells collected from a subject (e.g., by ink-jet printing, the autologous cells and the scaffold, separately or together), and then (b) implanting the autologous tissue implant in said subject.
Devices And Methods For Treating Spinal Cord Tissue
Louis C. Argenta - Winston-Salem NC, US David L. Carroll - Winston-Salem NC, US Nicole H. Levi - Winston-Salem NC, US Jie Liu - Winston-Salem NC, US Michael J. Morykwas - Winston-Salem NC, US Stephen Tatter - Winston-Salem NC, US
International Classification:
A61F 2/02
US Classification:
623 2374
Abstract:
The present invention provides devices and methods that treat damaged spinal cord tissue, such as spinal tissue damaged by disease, infection, or trauma, which may lead to the presence of swelling, compression, and compromised blood flow secondary to interstitial edema.
Apparatus And Method For Cardiac Tissue Modulation By Topical Application Of Vacuum To Minimize Cell Death And Damage
Louis C. Argenta - Winston-Salem NC, US David L. Carroll - Winston-Salem NC, US James E. Jordan - Clemmons NC, US Nicole H. Levi - Winston-Salem NC, US Jie Liu - Winston-Salem NC, US Michael J. Morykwas - Winston-Salem NC, US William D. Wagner - Clemmons NC, US
International Classification:
A61H 7/00
US Classification:
601 6
Abstract:
A method and apparatus are provided for treating cardiac tissue to modulate ischemic heart tissue with topical sub-atmospheric pressure to minimize cell death and damage.
David L. Carroll - Winston-Salem NC, US Faith M. Coldren - Strasbourg, FR Nicole H. Levi - Winston-Salem NC, US Lawrence X. Webb - Winston-Salem NC, US William D. Wagner - Clemmons NC, US Thomas L. Smith - Winston-Salem NC, US Brian Werner - Lancaster PA, US J. Baxter Mcguirt - Winston-Salem NC, US Manoj Namboothiry - West Lafayette IN, US
Assignee:
WAKE FOREST UNIVERSITY HEALTH SCIENCES - Winston-Salem NC WAKE FOREST UNIVERSITY - Winston-Salem NC
International Classification:
A61B 5/103
US Classification:
600587
Abstract:
The present invention provides a method of sensing pressure in a region of interest by providing a plurality of metallic particles operatively associated with one another in the region of interest (for example, wherein the metallic particles sustain a plasmon upon excitation), and with the metallic particles configured or positioned in relationship to one another so that a physical property of the particles (for example, the energy of the plasmon) varies in response to pressure; measuring the physical property of the metallic particles that varies in response to pressure; and then determining the pressure in the region of interest from the detected physical property (e.g., resistance, energy of the plasmon). Compositions, articles and formulations for carrying out the method in industrial and biomedical applications are also described.
The present invention relates to compositions and methods for treating cancer and, in particular, to composition and methods comprising nanostructures. In one embodiment, the present invention provides a composition comprising a mixture, the mixture comprising at least one nanoparticle and at least one chemotherapeutic.
Device And Method For Treating Central Nervous System Pathology
WAKE FOREST UNIVERSITY HEALTH SCIENCES - Winston-Salem NC, US David L. Carroll - Winston-Salem NC, US Nicole H. Levi - Winston-Salem NC, US Michael J. Morykwas - Winston-Salem NC, US Stephen Tatter - Winston-Salem NC, US William D. Wagner - Clemmons NC, US Jie Liu - Woodbury MN, US
Assignee:
WAKE FOREST UNIVERSITY HEALTH SCIENCES - Winston-Salem NC
International Classification:
A61H 7/00
US Classification:
601 6
Abstract:
The present invention relates generally to a device and method for treating tissues of the central nervous system and more particularly, but not exclusively, to a device and method for treating the brain tissue.
Devices And Methods For Treating Spinal Cord Tissue
- Winston-Salem NC, US David L. Carroll - Winston-Salem NC, US Nicole H. Levi - Winston-Salem NC, US Jie Liu - Woodbury MN, US Michael J. Morykwas - Winston-Salem NC, US Stephen Tatter - Winston-Salem NC, US William D. Wagner - Clemmons NC, US
International Classification:
A61M 1/00 A61F 13/00
Abstract:
The present invention provides devices and methods that treat damaged spinal cord tissue, such as spinal tissue damaged by disease, infection, or trauma, which may lead to the presence of swelling, compression, and compromised blood flow secondary to interstitial edema.
In one aspect, composite polymeric compositions are described herein which, in some embodiments, are thermally responsive to electromagnetic radiation for the destruction of microbes and associated biofilms. Briefly, a composite polymeric composition comprises a polymeric matrix and photo-thermal particles comprising conjugated polymer dispersed in the polymeric matrix, the photo-thermal particles providing sufficient heat to destroy microbial species upon irradiation with infrared radiation.
Effie Moore, Brittany Arrowood, Maggie Steadman, Jessica Dills, Ryan Wall, C O, Luke Greene, Shamecka Cook, Julia Laughter, Irving Santibanez, Miguel Santibanez