Nisha Gupta

US Patent:

8545459, Oct 1, 2013

Filed:

Feb 25, 2009

Appl. No.:

12/392544

Inventors:

Nisha Gupta - Audubon PA, US
Joel Rosenblatt - Pottstown PA, US

Assignee:

Teleflex Medical Incorporated - Durham NC

International Classification:

A61M 25/00
B05D 3/00

US Classification:

604266, 427 23, 605508, D24112

Abstract:

A medical device includes a base material having an immobilized fibrinolytic enzyme and dextran sulfate. The dextran sulfate has a molecular weight that is less than 40 kilo dalton (kDa). The medical device is formed from at least a base material. A fibrinolytic enzyme is immobilized on the base material. The fibrinolytic enzyme is stabilized with a dextran sulfate having a molecular weight of less than 40 (kDa).

US Patent:

8617120, Dec 31, 2013

Filed:

Feb 16, 2012

Appl. No.:

13/398480

Inventors:

David T. Rowe - Sinking Spring PA, US
Rodney W. Denlinger - Lancaster PA, US
Joel S. Rosenblatt - Pottstown PA, US
Nisha Gupta - Audubon PA, US
Joseph A. Runkle - Lititz PA, US
Jeffrey M. Vitullo - Pottstown PA, US
Philip D. Schmidt - Rougemont NC, US
William J. Vojtasek - Wyomissing PA, US

Assignee:

Arrow International, Inc. - Reading PA

International Classification:

A61M 5/32
A61M 5/178
A61M 5/00

US Classification:

604192, 604263, 60416408

Abstract:

An embodiment in accordance with the present invention provides an integrated syringe-device which can store a volume of fluid for infusion, can connect via an air-tight connector to another device (such as a luer connector), can flush fluid through the connector into the other device, and can deliver a cap that forms an air-tight closure to the device connector.

US Patent:

20100189808, Jul 29, 2010

Filed:

Jan 26, 2010

Appl. No.:

12/693753

Inventors:

Nisha Gupta - Audubon PA, US
Erin Peters - Hamburg PA, US
Joel Rosenblatt - Pottstown PA, US

Assignee:

TELEFLEX MEDICAL INCORPORATED - Durham NC

International Classification:

A61K 31/737
A61K 33/04
A61K 33/20
A61K 33/18
A61K 33/40
A61K 33/38
A61K 33/24
A61P 31/04
A61P 11/00
A61P 11/10
A61M 1/00
A46B 9/04
A61M 35/00

US Classification:

424616, 514 59, 424713, 424665, 424661, 424667, 424670, 424618, 424653, 604523, 151671, 604 1

Abstract:

A composition for dissolving or reducing the viscosity of sputum on a surface of a device includes an effective amount of glycerol and an effective amount of dextran sulfate in a saline solution. The effective amount of glycerol is between about 30-50% and the effective amount of dextran sulfate is between about 10-30%. The composition may further include an antimicrobial agent.

US Patent:

20100196434, Aug 5, 2010

Filed:

May 21, 2008

Appl. No.:

12/451773

Inventors:

Nisha Gupta - Audubon PA, US
Joel Rosenblatt - Pottstown PA, US
Daniel J. Spangler - Wernersville PA, US

Assignee:

ARROW INTERNATIONAL, INC. - Reading PA

International Classification:

A61K 9/00
A61K 38/48
A61K 31/155
A61K 31/136
A61K 31/65
A61K 31/496

US Classification:

424423, 424 9463, 424 9464, 514635, 514648, 514152, 51425411

Abstract:

Implantable catheters are provided which comprise an antimicrobial agent incorporated in a coating or bulk distributed, in combination with a fibrinolytic agent incorporated in a top coating.

US Patent:

20100233288, Sep 16, 2010

Filed:

Mar 11, 2009

Appl. No.:

12/401829

Inventors:

Nisha Gupta - Audubon PA, US
Joel Rosenblatt - Pottstown PA, US
Elaine Steinke - Morgantown PA, US

Assignee:

Teleflex Medical Incorporated - Durham NC

International Classification:

A61K 33/26

US Classification:

424608

Abstract:

A medical device includes a structure configured for introduction to a vascular system of a patient. The structure including a surface having sodium nitroprusside and silver disposed thereupon. The sodium nitroprusside has a concentration sufficient to reduce thrombosis. To make the medical device, a base material is impregnated with sodium nitroprusside, the medical device is formed from the base material, and the medical device is coated with an antimicrobial agent.

US Patent:

20120052185, Mar 1, 2012

Filed:

Nov 9, 2011

Appl. No.:

13/292636

Inventors:

Nisha Gupta - Audubon PA, US
Joel Rosenblatt - Pottstown PA, US
Elaine Steinke - Morgantown PA, US

Assignee:

Teleflex Medical Incorporated - Durham NC

International Classification:

A61M 25/00
D01D 5/24

US Classification:

427 228, 2642091

Abstract:

A medical device includes a structure configured for introduction to a vascular system of a patient. The structure including a surface having sodium nitroprusside and silver disposed thereupon, The sodium nitroprusside has a concentration sufficient to reduce thrombosis. To make the medical device, a base material is impregnated with sodium nitroprusside, the medical device is formed from the base material, and the medical device is coated with an antimicrobial agent.

US Patent:

20140030303, Jan 30, 2014

Filed:

Sep 30, 2013

Appl. No.:

14/041947

Inventors:

Nisha GUPTA - Audubon PA, US

Assignee:

Teleflex Medical Incorporated - Durham NC

International Classification:

A61L 33/06
A61L 33/00

US Classification:

424409, 424 943, 604266

Abstract:

A medical device includes a base material having an immobilized enzyme and dextran sulfate. The dextran sulfate has a molecular weight that is less than 40 kilo dalton (kDa). The medical device is formed from at least a base material. An enzyme is immobilized on the base material. The enzyme is stabilized with a dextran sulfate having a molecular weight of less than 40 (kDa).

US Patent:

20200171211, Jun 4, 2020

Filed:

Feb 10, 2020

Appl. No.:

16/786791

Inventors:

- Wayne PA, US
Nisha GUPTA - Reading PA, US
Greg ETTER - Reading PA, US
Kevin SECHRIST - Reading PA, US
Molly STEWART - Reading PA, US
Igor TENTLER - Reading PA, US
Al WILLIAMS - Reading PA, US

International Classification:

A61L 29/16
A61L 29/10
A61L 29/08
A61M 25/00
A61L 29/06

Abstract:

Provided are formulations and related methods, for coating or impregnating a medical device, as well as a coated or impregnated medical device, for example, a device that is a catheter or cannula, where a different formulation may be used for interior surface of device and for exterior surface of the device.