Nora Bayani
age ~65
from Berkeley, CA
- Also known as:
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- Nora B Kazerouni
- Bayani N Kazerouni
- Nora Bayany
- Phone and address:
- 1498 Summit Rd, Berkeley, CA 94708
Nora Bayani Phones & Addresses
- 1498 Summit Rd, Berkeley, CA 94708
- El Cerrito, CA
- San Jose, CA
- 775 Watson Canyon Ct, San Ramon, CA 94582
- Cupertino, CA
- Los Altos, CA
Us Patents
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Pik3Ca Mutation Status And Sash1 Expression Predicts Synergy Between Lapatinib And An Akt Inhibitor In Her2 Positive Breast Cancer
view source -
US Patent:20130331405, Dec 12, 2013
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Filed:Jun 12, 2012
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Appl. No.:13/494918
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Inventors:James E. Korkola - West Linn OR, US
Joe W. Gray - Lake Oswego OR, US
Nora Bayani - Berkeley CA, US -
Assignee:THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA
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International Classification:C12Q 1/68
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US Classification:51426624, 435 612, 436501
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Abstract:Methods for identifying a cancer patient, such as a breast cancer patient, suitable for treatment with a 4-anilinoquinazoline kinase inhibitor, such as lapatinib, and an AKT inhibitor, comprising detecting modulated expression of HER2 (ERBB2) and SASH1 or protein encoded thereof and detecting PIK3CA mutation status. High levels of expression in HER2 and high levels of SASH1 and/or positive PIK3CA mutation status indicate a patient that is suitable for treatment with a 4-anilinoquinazoline kinase inhibitor, such as lapatinib and an AKT inhibitor.
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