Oliver H Meek

US Patent:

20090170214, Jul 2, 2009

Filed:

Dec 29, 2008

Appl. No.:

12/345285

Inventors:

Oliver H. Meek - Austin TX, US
Roland Schneider - Austin TX, US
Harold N. Baker - Austin TX, US

Assignee:

LUMINEX CORPORATION - Austin TX

International Classification:

G01N 21/64
G01N 21/76

US Classification:

436172, 422 52

Abstract:

An optical analysis flow system and a method of assay analysis includes a means for facilitating activation of a luminescent material coupled to particles entrained within a fluid assay, wherein the means is arranged such that the activation of the luminescent material is conducted at a site along a flow path of the fluid assay prior to an examination zone of the optical analysis flow system. The method further includes measuring luminescent light emitting from the particles as they flow through the examination zone. Another method of assay analysis includes respectively measuring different types of luminescent light emission from a first set and a second set of particles comprising a fluid assay. An optical analysis system includes at least two distinct means for respectively facilitating the activation of at least two different luminescent materials coupled to particles of a fluid assay.

US Patent:

52022706, Apr 13, 1993

Filed:

Aug 30, 1990

Appl. No.:

7/576085

Inventors:

Frank S. Ungemach - Lake Villa IL
Daniel S. Nam - Chicago IL
Oliver H. Meek - Flower Mound TX

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

G01N 33533
C07D45102
C07K 1300

US Classification:

436537

Abstract:

The present invention is directed to a fluorescence polarization assay for benzoyl ecgonine and substituted benzoyl ecgonine compounds in biological fluids, and to a method of making reagents therefor. Specifically, tracers, immunogens and antibodies are disclosed. The tracers and the immunogens are made from substituted benzoyl ecgonine compounds. A fluorescein moiety is included in the tracer, while a poly(amino acid) forms a part of the immunogen. The assay is conducted by measuring the degree of polarization retention of plane polarized light that has been passed through a sample containing antiserum and tracer.