Pamela S Norton

US Patent:

20130142827, Jun 6, 2013

Filed:

Jun 24, 2011

Appl. No.:

13/805844

Inventors:

Timothy M. Block - Doylestown PA, US
Anand Mehta - Lansdale PA, US
Pamela Norton - Blue Bell PA, US

Assignee:

PHILADELPHIA HEALTH & EDUCATION CORPORATION D/B/A - PHILADELPHIA PA

International Classification:

A61K 39/29
A61K 31/45
A61K 31/437
A61K 31/7072
A61K 31/522

US Classification:

4242271, 4242041, 530395, 4353201

Abstract:

Provided are methods and compositions that can be used to treat subjects having a viral infection by provoking an immune response using newly discovered antigens that are non-naturally occurring variations on viral glycoproteins. For example, provided are viral glycoproteins or a fragments thereof, or, DNA constructs encoding for such viral glycoproteins or fragments thereof, wherein the glycoprotein or fragment comprises a glycosylation sequon that includes a non-templated aspartic acid residue.