Pankaj Gupta

US Patent:

20060292157, Dec 28, 2006

Filed:

Dec 2, 2005

Appl. No.:

11/292571

Inventors:

Paul Fisher - Scarsdale NY, US
Pankaj Gupta - New York NY, US

Assignee:

THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK - New York NY

International Classification:

A61K 39/395
A61K 38/17
A61K 48/00
C07K 16/30
C07K 14/82
C07H 21/04

US Classification:

424155100, 514012000, 514044000, 435069100, 435320100, 435325000, 530350000, 536023500, 530388800

Abstract:

The invention relates to the mda-7 gene, its encoded protein and fragments of the protein. Several of these fragments of the MDA-7 protein exhibit antiproliferative activity and/or inhibited the activity of intact MDA-7. Accordingly, the invention provides, among other things, for methods and compositions that may be used in the treatment of disorders of cell proliferation, including cancer.

US Patent:

20220363743, Nov 17, 2022

Filed:

Jun 17, 2022

Appl. No.:

17/842904

Inventors:

- Ingelheim am Rhein, DE
Chao ZHENG - Briarcliff Manor NY, US
Michael DZIEGELEWSKI - Newburgh NY, US
Pankaj GUPTA - Scarsdale NY, US

International Classification:

C07K 16/22

Abstract:

The present invention relates to new anti-angiopoietin 2 (ANGPT2) neutralizing antibodies for therapeutic and diagnostic methods and composition using them.

US Patent:

20210380696, Dec 9, 2021

Filed:

May 24, 2021

Appl. No.:

17/328050

Inventors:

- Ingelheim am Rhein, DE
Nicole K. GARAFFA - Monroe CT, US
Pankaj GUPTA - Scarsdale NY, US
Priyanka GUPTA - Danbury CT, US
Fei HAN - Sandy Hook CT, US
Aaron Timothy KARLAK - Beacon Falls NY, US
Dongmei LIU - Oxford CT, US
Ivo LORENZ - Brooklyn NY, US
Mouhamadou Lamine MBOW - Echichens, CH
Miguel E. MORENO-GARCIA - Sandy Hook CT, US
Joseph A. MOZDZIERZ - Mahopac NY, US
Kerry L.M. RALPH - Bethel CT, US
Abdulsalam SHAABAN - Ridgefield CT, US
Della M. WHITE - Brookfield CT, US
Helen Haixia WU - Danbury CT, US
Guangwei YANG - Cheshire CT, US

International Classification:

C07K 16/28

Abstract:

The present invention relates to new anti-PD-1 (Programmed cell death 1) antibodies and antigen-binding fragments thereof for therapeutic and diagnostic methods and compositions using them.

US Patent:

20210363273, Nov 25, 2021

Filed:

May 18, 2021

Appl. No.:

17/323844

Inventors:

- Ingelheim am Rhein, DE
Pankaj GUPTA - Scarsdale NY, US
Daniel Christopher ROWE - Ridgefield CT, US
Justin M. SCHEER - Ridgefield CT, US
Abdallah SOUABNI - Vienna, AT
Inigo TIRAPU - Vienna, AT
Joseph Ronald TUMANG - Danbury CT, US

International Classification:

C07K 16/40
C07K 16/28
A61P 35/00

Abstract:

This invention relates to binding molecules that bind specifically to CD137 and FAP and their use in medicine, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of cancer.

US Patent:

20210107998, Apr 15, 2021

Filed:

Oct 22, 2020

Appl. No.:

17/076894

Inventors:

- Ingelheim Am Rhein, DK
- Rockville MD, US
Rachel Rebecca BARRETT - Bethel CT, US
Leslie S. JOHNSON - Damestoen MD, US
Pankaj GUPTA - Scarsdale NY, US
Sarah LOW - Carmel NY, US
Haixia WU - Danbury CT, US

International Classification:

C07K 16/46
C07K 16/28
C12N 15/63
C12N 5/10
C07K 16/24

Abstract:

The disclosure relates to compounds specific for IL23A and BAFF, compositions comprising the compounds, and methods of use thereof. Nucleic acids, cells, and methods of production related to the compounds and compositions are also disclosed.

US Patent:

20210087282, Mar 25, 2021

Filed:

Sep 24, 2020

Appl. No.:

17/030421

Inventors:

- Ingelheim am Rhein, DE
Pankaj GUPTA - Scarsdale NY, US
Fei HAN - Sandy Hook CT, US
Yining HUANG - Danbury CT, US
Sarah LOW - Carmel NY, US
Juergen PRESTLE - Biberach an der Riss, DE
Leo THOMAS - Biberach an der Riss, DE

International Classification:

C07K 16/28
A61K 9/00
C12N 15/63
A61P 27/02

Abstract:

Disclosed are antibodies and fragments thereof that target the A-domain of Neuropilin-1 (Nrp1A). Also disclosed are methods of using the anti-Nrp1A antibodies for the treatment of various diseases or disorders.

US Patent:

20210059684, Mar 4, 2021

Filed:

Aug 27, 2020

Appl. No.:

17/004282

Inventors:

- St. Paul MN, US
Dan E. Gutfinger - Agoura Hills CA, US
Pankaj Gupta - Maple Grove MN, US
Brian Perszyk - Shoreview MN, US
Alex Bloomquist - Mound MN, US
Hanna Williams - St. Louis Park MN, US
Erika Beek - Bloomington MN, US

International Classification:

A61B 17/12

Abstract:

The present disclosure is directed to embodiments and methods of reducing or eliminating erosion resulting from the use of an occluder. In particular, the present disclosure is directed to reducing or eliminating erosion resulting from the use of an occluder while maintaining the fundamental function and effectiveness of the occluder with an improved occluder braid pattern. The embodiments and methods disclosed herein reduce or eliminate erosion, for example, by reducing the friction and force of an occluder on cardiac tissue and/or by increasing occluder disc compliance to cardiac structures and movement.

US Patent:

20200407435, Dec 31, 2020

Filed:

Jun 25, 2020

Appl. No.:

16/911419

Inventors:

- Ingelheim am Rhein, DE
Chao ZHENG - Briarcliff Manor NY, US
Michael DZIEGELEWSKI - Newburgh NY, US
Pankaj GUPTA - Scarsdale NY, US
Thierry BOUYSSOU - Warthausen, DE
Paul NICKLIN - Biberach an der Riss, DE

International Classification:

C07K 16/22

Abstract:

The present invention relates to new anti-angiopoietin 2 (ANGPT2) neutralizing antibodies for therapeutic and diagnostic methods and composition using them.