Patrick S Adams

US Patent:

20050080830, Apr 14, 2005

Filed:

Oct 14, 2003

Appl. No.:

10/685317

Inventors:

Feng Gao - Fort Collins CO, US
Patrick Adams - Loveland CO, US
David Kjosness - Longmont CO, US

International Classification:

G06F001/02

US Classification:

708277000

Abstract:

An exponential signal generator having a memory, a scale unit and an adder. A value stored in the memory is scaled and added to itself to produce a new value for storing in the memory. The exponential signal is represented by the exponential value.

US Patent:

20130204107, Aug 8, 2013

Filed:

Jan 23, 2013

Appl. No.:

13/747921

Inventors:

THE OHIO STATE UNIVERSITY - Columbus OH, US
Wu Lu - Dublin OH, US
Leonard J. Brillson - New Albany OH, US
Gregg A. Hadley - New Albany OH, US
Patrick Adams - Gahanna OH, US
Ronald P. Pelletier - Columbus OH, US
Paul R. Berger - Columbus OH, US

Assignee:

THE OHIO STATE UNIVERSITY - Columbus OH

International Classification:

G01N 27/414
A61B 5/00

US Classification:

600345, 422 69, 436149, 436518, 436 86, 436 94, 436 91, 435 71, 4352871

Abstract:

Disclosed are field effect transistor-based (FET-based) sensors for the rapid and accurate detection of analytes both in vivo and in vitro. The FET-based sensors can include a substrate, a channel disposed on the substrate, a source electrode and a drain electrode electrically connected to the channel, and a recognition element for an analyte of interest immobilized on the surface of the channel via a linking group. The distance between the recognition element and the channel can be configured such that association of the analyte of interest with the recognition element induces a change in the electrical properties of the channel. In this way, an analyte of interest can be detected by measuring a change in an electrical property of the channel. Also provided are devices, including probes and multi-well plates, incorporating the FET-based sensors.