Patrick William Mccarthy

US Patent:

8173750, May 8, 2012

Filed:

Oct 27, 2010

Appl. No.:

12/926143

Inventors:

Wojciech Jakubowski - Pittsburgh PA, US
Patrick McCarthy - Pittsburgh PA, US
Nicolay Tsarevsky - Dallas TX, US
James Spanswick - Pittsburgh PA, US

Assignee:

ATRP Solutions, Inc. - Pittsburgh PA

International Classification:

C08F 287/00
C08F 285/00

US Classification:

525244, 525 50, 525 70, 525191, 525193, 525241, 525301, 525221, 525227, 525223

Abstract:

A polymer composition comprising star macromolecules is provided. Each star macromolecule has a core and five or more arms, wherein the number of arms within a star macromolecule varies across the composition of star molecules. The arms on a star are covalently attached to the core of the star; each arm comprises one or more (co)polymer segments; and at least one arm and/or at least one segment exhibits a different solubility from at least one other arm or one other segment, respectively, in a reference liquid of interest.

US Patent:

8569421, Oct 29, 2013

Filed:

Apr 23, 2010

Appl. No.:

12/799411

Inventors:

Wojciech Jakubowski - Pittsburgh PA, US
Patrick McCarthy - Pittsburgh PA, US
Nicolay Tsarevsky - Dallas TX, US
James Spanswick - Pittsburgh PA, US

Assignee:

ATRP Solutions, Inc. - Pittsburgh PA

International Classification:

C08F 287/00
C08F 285/00

US Classification:

525244, 525 50, 525 70, 525191, 525193, 525241, 525301, 525221, 525227, 525223

Abstract:

A polymer composition comprising star macromolecules is provided. Each star macromolecule has a core and five or more arms, wherein the number of arms within a star macromolecule varies across the composition of star molecules. The arms on a star are covalently attached to the core of the star; each arm comprises one or more (co)polymer segments; and at least one arm and/or at least one segment exhibits a different solubility from at least one other arm or one other segment, respectively, in a reference liquid of interest.

US Patent:

8604132, Dec 10, 2013

Filed:

Mar 2, 2012

Appl. No.:

13/410700

Inventors:

Wojciech Jakubowski - Pittsburgh PA, US
Patrick McCarthy - Pittsburgh PA, US
Nicolay Tsarevsky - Dallas TX, US
James Spanswick - Wheaton IL, US

Assignee:

ATRP Solutions, Inc. - Pittsburgh PA

International Classification:

C08F 267/00
C08F 285/00

US Classification:

525244, 525 50, 525 70, 525191, 525193, 525241, 525301, 525221, 525227, 525223

Abstract:

A polymer composition comprising star macromolecules is provided. Each star macromolecule has a core and five or more arms, wherein the number of arms within a star macromolecule varies across the composition of star molecules. The arms on a star are covalently attached to the core of the star; each arm comprises one or more (co)polymer segments; and at least one arm and/or at least one segment exhibits a different solubility from at least one other arm or one other segment, respectively, in a reference liquid of interest.

US Patent:

20110263722, Oct 27, 2011

Filed:

Apr 23, 2010

Appl. No.:

12/799412

Inventors:

Wojciech Jakubowski - Pittsburgh PA, US
Patrick McCarthy - Pittsburgh PA, US
Nicolay Tsarevsky - Dallas TX, US
James Spanswick - Pittsburgh PA, US

International Classification:

C08F 20/06
A61K 47/32

US Classification:

5147726, 526214

Abstract:

The present invention relates to the preparation and use of well defined star macromolecules wherein the composition of the arms are selected to induce self assembly when the multi-arm segmented star macromolecules are dispersed in a liquid. The self assembled star macromolecules modify the rheology of the dispersing media. When targeting use in aqueous based systems the inner shell of the star macromolecules comprise non-ionizable monomer units. Compositions comprising the self assemblable star macromolecules are suitable for use as rheology modifiers in a number of applications including cosmetic and personal care compositions.

US Patent:

20110286935, Nov 24, 2011

Filed:

May 17, 2011

Appl. No.:

13/109256

Inventors:

Patrick McCarthy - Pittsburgh PA, US
James Spanswick - Pittsburgh PA, US

Assignee:

ATRP Solutions, Inc. - Pittsburgh PA

International Classification:

A61K 49/18
A61K 39/395
A61P 35/00
A61K 9/00
A61K 49/00
B82Y 15/00
B82Y 5/00

US Classification:

424 934, 424400, 4241781, 424 91, 424 96, 977700, 977906, 977927

Abstract:

A universal drug delivery platform for monoclonal antibody-based therapeutics is described. This universal platform resolves the problems of immunogenic response associated with the present monoclonal antibody based therapeutics by providing a multifunctional nano-device which comprises a well defined core/shell nano-structure that can function as a drug delivery platform linked to a monoclonal antibody through a single linking group.

US Patent:

20130296495, Nov 7, 2013

Filed:

Oct 26, 2011

Appl. No.:

13/881268

Inventors:

Wojciech Jakubowski - Pittsburgh PA, US
Patrick McCarthy - Pittsburgh PA, US
Nicolay Tsarevsky - Dallas TX, US
James Spanswick - Pittsburgh PA, US

Assignee:

ATRP Solutions, Inc. - Pittsburgh PA

International Classification:

C08F 265/04

US Classification:

525242

Abstract:

A polymer composition comprising star macromolecules is provided. Each star macromolecule has a core and five or more arms, wherein the number of arms within a star macromolecule varies across the composition of star molecules. The arms on a star are covalently attached to the core of the star; each arm comprises one or more (co)polymer segments; and at least one arm and/or at least one segment exhibits a different solubility from at least one other arm or one other segment, respectively, in a reference liquid of interest.

US Patent:

20140024779, Jan 23, 2014

Filed:

Sep 25, 2013

Appl. No.:

14/036993

Inventors:

Patrick McCarthy - Pittsburgh PA, US
Nicolay Tsarevsky - Dallas TX, US
James Spanswick - Pittsburgh PA, US

Assignee:

ATRP Solutions, Inc. - Pittsburgh PA

International Classification:

C08F 293/00

US Classification:

525 94

Abstract:

A polymer composition comprising star macromolecules is provided. Each star macromolecule has a core and five or more arms, wherein the number of arms within a star macromolecule varies across the composition of star molecules. The arms on a star are covalently attached to the core of the star; each arm comprises one or more (co)polymer segments; and at least one arm and/or at least one segment exhibits a different solubility from at least one other arm or one other segment, respectively, in a reference liquid of interest.

US Patent:

20140024783, Jan 23, 2014

Filed:

Sep 25, 2013

Appl. No.:

14/037031

Inventors:

Patrick McCarthy - Pittsburgh PA, US
Nicolay Tsarevsky - Dallas TX, US
James Spanswick - Pittsburgh PA, US

Assignee:

ATRP Solutions, Inc. - Pittsburgh PA

International Classification:

C08F 299/04

US Classification:

525299

Abstract:

A polymer composition comprising star macromolecules is provided. Each star macromolecule has a core and five or more arms, wherein the number of arms within a star macromolecule varies across the composition of star molecules. The arms on a star are covalently attached to the core of the star; each arm comprises one or more (co)polymer segments; and at least one arm and/or at least one segment exhibits a different solubility from at least one other arm or one other segment, respectively, in a reference liquid of interest.