Paul Edward Carpenter

US Patent:

20120042354, Feb 16, 2012

Filed:

Aug 13, 2010

Appl. No.:

12/806512

Inventors:

Anthony Vitiello - Mentor OH, US
Anoop Kanthan - New York NY, US
Paul Edward Carpenter - Stamford CT, US

Assignee:

Morgan Stanley - New York NY

International Classification:

G06F 21/00

US Classification:

726 1

Abstract:

Various embodiments are directed to entitlements clearance. For example, an entitlement clearance request may be received from a provisioning application. The entitlement clearance request may comprise an indication of a subject entitlement and an indication of a subject user. An indication of user characteristics describing the subject user and an indication of existing entitlements held by the subject user may be received. A plurality of entitlements conflict rules may be applied to the existing entitlements, the subject entitlement and the user characteristics to determine whether an entitlements conflict exists in view of the subject entitlement. In addition, a completion indication of whether the entitlements conflict exists in view of the subject entitlement may be returned. Provided that the entitlements conflict exists, the completion indication may comprise an indication of at least one entitlements conflict rule selected from the plurality of entitlements conflict rules that would be violated by the subject entitlement.

US Patent:

20120064177, Mar 15, 2012

Filed:

Sep 10, 2010

Appl. No.:

12/879090

Inventors:

Paul Carpenter - Newtown CT, US

International Classification:

A61K 33/14
A61K 36/61
A61P 29/00
A61K 31/375
A61P 37/00
A61K 31/165
A61K 36/886

US Classification:

424665, 514627, 424742, 424744, 514474

Abstract:

The present invention relates to a method of preparing an intranasal composition including from about 0.0010-0.0040% by weight capsaicin, from about 0.50-0.90% by weight hydroxypropyl methylcellulose, from about 0.010-0.080% by weight n-alkyl dimethyl benzyl ammonium chloride (Quat), and various moisturizing and irrigation agents, wherein the method includes dissolving the above components in water to form an aqueous solution; and filtering the aqueous solution to form an intranasal composition. The present invention further relates to an intranasal drug delivery composition, which includes from about 0.0010-0.0040% by weight capsaicin, from about 0.50-0.90% by weight hydroxypropyl methylcellulose, from about 0.010-0.080% by weight n-alkyl dimethyl benzyl ammonium chloride (Quat), and various moisturizing and irrigation agents. The present invention further relates to a method to increase tolerability and reduce burning from capsaicin when applied to nasal mucosa in the form of an intranasal composition, which includes combining capsaicin with the materials as noted above.