Paul Francis Dicesare

US Patent:

6471069, Oct 29, 2002

Filed:

Nov 30, 2000

Appl. No.:

09/727162

Inventors:

Fu-Chung Lin - Wayne NJ
Paul C. DiCesare - Norwalk CT
Jeffrey Radziunas - Wallingford CT

Assignee:

Becton Dickinson and Company - Franklin Lakes NJ

International Classification:

B01D 2126

US Classification:

210359, 210515, 210516, 210518, 2103601, 494 16, 436177, 422 72, 422101, 422102

Abstract:

A device and method for separating heavier and lighter fractions of a fluid sample. The device includes a flexible collapsible inner container disposed within a substantially rigid outer container. A closure seals the open top end of the outer container. A filter assembly is sealingly mounted to the open top end of the inner container. The filter assembly includes a filter that permits lighter fractions to pass therethrough, while substantially blocking the heavier fractions. The filter assembly further includes a filter support having a slit valve registered with the filter. The slit valve opens in response to fluid pressure created by the lighter fractions for permitting the lighter fractions to flow therethrough. A fluid sample is delivered to the inner container and the device is subjected to centrifugation whereby the centrifugal load causes the filter assembly to move toward the bottom end of the outer container and thereby enable the lighter fraction of the fluid sample to flow through the slit valve and into the space between the inner and outer containers. The slit valve closes upon termination of the centrifugal load such that separation between the heavier and lighter fractions of the fluid sample are maintained.

US Patent:

6860882, Mar 1, 2005

Filed:

Jun 9, 2003

Appl. No.:

10/457176

Inventors:

Christopher Austin Battles - New Haven CT, US
Paul DiCesare - Easton CT, US
Patrick Gutelius - Shelton CT, US
Daniel Paul Ferriera - Milford CT, US
Richard Barry Stevens - Mashpee MA, US
John Buonanno - Bristol RI, US
Sharon A. Mulligan - Attleboro MA, US

Assignee:

Codman & Shurtleff, Inc. - Raynham MA

International Classification:

A61B018/18

US Classification:

606 51, 606 52

Abstract:

In accordance with a currently preferred exemplary embodiment, the present invention involves an electro-surgical bipolar forceps having a first member, a second member, and a tip assembly. The first member has a first insert tube extending from a distal end thereof and a handle disposed at a proximal end thereof. The second member has a second insert tube extending from a distal end thereof and a handle disposed at a proximal end thereof. At least one of the first and second insert tube has an inner surface, a portion of which is covered with an electrically insulating material. The first tip assembly has a proximal end and a distal end. The proximal end of the first tip assembly is selectively engageable with one of the first and second insert tubes. The first tip assembly includes an electrically conductive tip disposed at the distal end of the first tip assembly.

US Patent:

6926723, Aug 9, 2005

Filed:

May 27, 1994

Appl. No.:

08/250657

Inventors:

Paul J. Mulhauser - New York NY, US
Paul C. DiCesare - Norwalk CT, US

Assignee:

C.R. Bard Inc. - Murray Hill NJ

International Classification:

A61B017/00

US Classification:

606151

Abstract:

An implantable prosthesis and device and method for loading and delivering the implantable prosthesis to a trocar cannula. The implantable prosthesis includes a body portion sufficient to extend across and occlude a defect opening and a semi-rigid ring for supporting the body portion. The implantable prosthesis may be provided with a sufficient hoop strength to prevent the body portion from collapsing into the defect opening. A loading and delivery tool includes a main body with a lumen sized to collapse the implantable prosthesis. An elongated shaft is rotatable to wind the implant into a slender configuration and axially moveable to advance the rolled-up implant into the trocar cannula. A cartridge extends from the main body and holds the implant in a normal expanded configuration.

US Patent:

6929645, Aug 16, 2005

Filed:

Feb 6, 2003

Appl. No.:

10/359495

Inventors:

Christopher Austin Battles - New Haven CT, US
Paul DiCesare - Easton CT, US
Patrick Gutelius - Monroe CT, US
Daniel Paul Ferriera - Milford CT, US
Richard Barry Stevens - Mashpee MA, US

Assignee:

Codman & Shurtleff, Inc. - Raynham MA

International Classification:

A61B018/18

US Classification:

606 51, 606205, 606 50

Abstract:

In accordance with a currently preferred exemplary embodiment, the present invention involves an electro-surgical bipolar forceps having a first member, a second member, and a tip assembly. The first member has a first insert tube extending from a distal end thereof and a handle disposed at a proximal end thereof. The second member has a second insert tube extending from a distal end thereof and a handle disposed at a proximal end thereof. At least one of the first and second insert tube has an inner surface, a portion of which is covered with an electrically insulating material. The first tip assembly has a proximal end and a distal end. The proximal end of the first tip assembly is selectively engageable with one of the first and second insert tubes. The first tip assembly includes an electrically conductive tip disposed at the distal end of the first tip assembly.

US Patent:

8449479, May 28, 2013

Filed:

Apr 29, 2005

Appl. No.:

11/568603

Inventors:

Jeffrey Radzuinas - Wallingford CT, US
Paul DiCesare - Easton CT, US
Christopher A. Battles - New Haven CT, US

Assignee:

Becton, Dickinson and Company - Franklin Lakes NJ

International Classification:

A61B 5/00

US Classification:

600583

Abstract:

The medical puncturing device () includes a housing () having a proximal end () and a distal end () and a skin puncturing assembly () within the housing. The skin puncturing assembly includes a movable carrier () and a skin puncturing element (). The skin puncturing element is adapted to puncture the skin of a patient. The carrier is movable from a retracted position wherein a distal tip of the skin puncturing element is disposed within the housing, to a puncturing position wherein the distal tip is exposed to puncture the skin of the patient. The carrier is moved from the retracted position to the puncturing position upon radial deformation of the housing. An internal guide () may be provided within the housing for guiding the movement of the carrier from the retracted position to the puncturing position.

US Patent:

20050197304, Sep 8, 2005

Filed:

Jul 8, 2004

Appl. No.:

10/886947

Inventors:

Paul DiCesare - Irvington NY, US

International Classification:

A61K048/00
A61K009/14

US Classification:

514044000, 424486000

Abstract:

The present invention relates to the application of nucleic acid therapy for the repair and regeneration of cartilage. The invention encompasses the introduction of naked DNA encoding bioactive agent(s), whose expression stimulates and otherwise facilitates the repair and regeneration of cartilage. The present invention provides DNA constructs for introduction to the site of cartilage damage. Pharmaceutical compositions comprising nucleic acid encoding one or more bioactive factor, optionally with a matrix or polymer, are provided. Methods for expression of bioactive agent(s) are provided. Methods for enhancing cartilage repair and/or regeneration comprising introduction of bioactive factors as naked DNA are further provided. Methods for the treatment or prevention of cartilage damage in various orthopaedic and rheumatologic conditions are provided.

US Patent:

20100174143, Jul 8, 2010

Filed:

Dec 1, 2009

Appl. No.:

12/628609

Inventors:

Michael E. Abrams - New York NY, US
Christopher A. Battles - Seymour CT, US
Paul DiCesare - Easton CT, US
Danial P. Ferreira - Milford CT, US
Gregory R. Hires - Fairfield CT, US

International Classification:

A61B 1/00

US Classification:

600121

Abstract:

A seal assembly which includes a housing defining a longitudinal axis, a proximal portion and a distal portion and including a bellows disposed along a length thereof. A first sealing membrane and a second sealing membrane associated with the proximal portion of the housing, each sealing membrane configured to create a substantially fluid-tight seal around a surgical instrument inserted therethrough. The bellows configured to allow at least a portion of the housing to move radially with respect to the longitudinal axis.

US Patent:

57662460, Jun 16, 1998

Filed:

Jan 7, 1994

Appl. No.:

8/178665

Inventors:

Paul J. Mulhauser - New York NY
Paul C. DiCesare - Norwalk CT

Assignee:

C. R. Bard, Inc. - Murray Hill NJ

International Classification:

A61F 206
A61B 1900

US Classification:

623 11

Abstract:

An implantable prosthesis and device and method for loading and delivering the implantable prosthesis to a trocar cannula. The implantable prosthesis includes a body portion sufficient to extend across and occlude a defect opening and a semi-rigid ring for supporting the body portion. The implantable prosthesis may be provided with a sufficient hoop strength to prevent the body portion from collapsing into the defect opening. A loading and delivery tool includes a main body with a lumen sized to collapse the implantable prosthesis. An elongated shaft is rotatable to wind the implant into a slender configuration and axially moveable to advance the rolled-up implant into the trocar cannula. A cartridge extends from the main body and holds the implant in a normal expanded configuration.