Paul D Mcnicholas

US Patent:

20100158992, Jun 24, 2010

Filed:

Mar 12, 2008

Appl. No.:

12/528944

Inventors:

Todd A. Black - New Providence NJ, US
Paul M. McNicholas - Westfield NJ, US
Scott S. Walker - Basking Ridge NJ, US
Yiming Xu - Princeton NJ, US
Pauline C. Ting - New Providence NJ, US

Assignee:

Schering Corporation - Kenilworth NJ

International Classification:

A61K 31/501
C07D 403/04
C07D 413/14
A61K 31/5377
A61K 9/127
A61K 31/7048
A61K 31/69
A61P 31/10

US Classification:

424450, 544238, 544121, 51425202, 5142365, 514 31, 514 64

Abstract:

There is disclosed a method for treating or preventing fungal infections comprising the administration of at least one glucan synthase inhibitor of a formula as described above in the specification or a pharmaceutically acceptable salt thereof; also claimed are methods of preparing pharmaceutical compositions comprising a compound as described above in the specification and a carrier, method of treating or preventing fungal infections comprising administration of combinations of glucan synthase inhibitor of a formula as described above in the specification and other antifungal agents, and method of treating or preventing fungal infections comprising administration of pharmaceutical compositions prepared according to a method described above in the specification, and a method of preparing a kit in a single package of the above described pharmaceutical composition and other antifungal agents.