Paul J Murray

US Patent:

6575021, Jun 10, 2003

Filed:

Apr 10, 2002

Appl. No.:

10/120199

Inventors:

Harold J. Kosasky - Chestnut Hill MA
Elias G. Noukas - Milford NH
Paul D. Murray - Carlisle MA
Alfredo O. Kenig - Carlisle MA

Assignee:

Boston Rheology, Inc. - Chestnut Hill MA

International Classification:

A61B 1000

US Classification:

73 5437, 73 5422, 73 5402

Abstract:

A sample surface component for an instrument the measures viscosity and viscoelasticity. The instrument has a cam, a follower arm, a flat spring, a plate fixture, and a removable plate assembly. The cam is a rotating circular disk with a spiral slot. A cam follower on the follower arm resides in the spiral slot so that the follower arm pivots about its fixed end as the cam rotates. The spring is attached to and collinear with the fixed end of the follower arm so that the spring pivots in the opposite direction as the follower arm. The sample surface component include a removable plate assembly with a lower plate and an upper plate with mating sample surfaces on which test fluid is placed. The lower plate fits into a lower jaw of the plate fixture that is attached to the instrument base. The upper plate fits into an upper jaw of the plate fixture attached to the free end of the spring. A fluid is placed on the lower sample surface.

US Patent:

6591663, Jul 15, 2003

Filed:

Apr 10, 2002

Appl. No.:

10/120202

Inventors:

Paul D. Murray - Carlisle MA
Alfredo O. Kenig - Carlisle MA
David Porat - Newton MA

Assignee:

Boston Rheology, Inc. - Chestnut Hill MA

International Classification:

G01N 1100

US Classification:

73 5437, 73 5422

Abstract:

A viscosity and viscoelasticity measuring instrument has a cam, a follower arm, a flat spring, a plate fixture, and a removable plate assembly. The cam is a rotating circular disk with a spiral slot. A cam follower on the follower arm resides in the spiral slot so that the follower arm pivots about its fixed end as the cam rotates. The spring is attached to and collinear with the fixed end of the follower arm so that the spring pivots in the opposite direction as the follower arm. The removable plate assembly has a lower plate and an upper plate with mating sample surfaces on which test fluid is placed. The lower plate fits into a lower jaw of the plate fixture that is attached to the instrument base. The upper plate fits into an upper jaw of the plate fixture attached to the free end of the spring. A fluid is placed on the lower sample surface.

US Patent:

8420380, Apr 16, 2013

Filed:

Apr 8, 2008

Appl. No.:

12/099717

Inventors:

Robert Fishman - Boston MA, US
Robert Havener - Lynnfield MA, US
Ihab Abdel Fattah - Andover MA, US
Anas Abdelazim - North Andover MA, US
Scott Newell - Ipswich MA, US
Tom Bishop - Wenham MA, US
Tamer Khayal - North Andover MA, US
Stanley Kyi - Andover MA, US
Ron Taylor - Chester NH, US
Doug Harriott - Melrose MA, US
Matthew De Remer - Allston MA, US
Paul Murray - Groton MA, US
John Sullivan - Groton MA, US
Mark Anderson - Danvers MA, US
Richard Bringham - North Andover MA, US
Michael Van Driel - Mirandola, IT
Waleed Hassanein - North Andover MA, US

Assignee:

TransMedics, Inc. - Andover MA

International Classification:

A01N 1/02

US Classification:

4352841, 435 12

Abstract:

Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.

US Patent:

20020121795, Sep 5, 2002

Filed:

Jan 22, 2002

Appl. No.:

10/054146

Inventors:

Paul Murray - Deer Park NY, US

International Classification:

B62D025/10

US Classification:

296/076000

Abstract:

A deck lock system for usage in the rear area of a sport utility vehicle and covering the entire rear area of the vehicle, the deck lock system comprising: a deck surface, which comprises a first deck surface panel, a second deck surface panel, and a third deck surface panel. Each panel is substantially horizontal to the floor of the vehicle, each panel attached together along distal edges by a hinge, allowing the first two panels to fold along a vertical axis. A faceplate is securely connected to the deck surface along a front edge, the faceplate extending downwardly from the deck surface in a substantially perpendicular relation, the faceplate extending inwardly from a right side of the vehicle to a left side. The faceplate faces the front of the vehicle; creating a front wall to complete an enclosed storage area. A rear vertical security panel is securely connected to the last rear deck surface panel along a rear inner edge extending downwardly from the deck surface panel in a substantially perpendicular relation. The rear security panel faces the rear of the vehicle, and is connectable to the rear deck surface panel to form a storage area for use when a vehicle seat is utilized. Through usage of the system, a plurality of storage configurations is created above and below the deck surface.

US Patent:

20090197240, Aug 6, 2009

Filed:

Apr 8, 2008

Appl. No.:

12/099715

Inventors:

Robert Fishman - Boston MA, US
Robert Havener - Lynnfield MA, US
Ihab Abdel Fattah - Andover MA, US
Anas Abdelazim - North Andover MA, US
Scott Newell - Ipswich MA, US
Tom Bishop - Wenham MA, US
Tamer Khayal - North Andover MA, US
Stanley Kyi - Andover MA, US
Ron Taylor - Chester NH, US
Doug Harriott - Melrose MA, US
Matthew De Remer - Allston MA, US
Paul Murray - Groton MA, US
John Sullivan - Groton MA, US
Mark Anderson - Danvers MA, US
Richard Bringham - North Andover MA, US
Michael Van Driel - Mirandola, IT
Waleed Hassanein - , US

Assignee:

TRANSMEDICS, INC - Andover MA

International Classification:

A01N 1/02
A61B 19/00

US Classification:

435 12, 12820024, 128898

Abstract:

Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.

US Patent:

20090197292, Aug 6, 2009

Filed:

Apr 8, 2008

Appl. No.:

12/099687

Inventors:

Robert Fishman - Boston MA, US
Robert Havener - Lynnfield MA, US
Ihab Abdel Fattah - Andover MA, US
Anas Abdelazim - North Andover MA, US
Scott Newell - Ipswich MA, US
Tom Bishop - Wenham MA, US
Tamer Khayal - North Andover MA, US
Stanley Kyi - Andover MA, US
Ron Taylor - Chester NH, US
Doug Harriott - Melrose MA, US
Matthew De Remer - Allston MA, US
Paul Murray - Groton MA, US
John Sullivan - Groton MA, US
Mark Anderson - Danvers MA, US
Richard Bringham - North Andover MA, US
Michael Van Driel - Mirandola, IT
Waleed Hassanein - , US

International Classification:

C12Q 1/02
C12M 1/00

US Classification:

435 29, 4352841

Abstract:

Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.

US Patent:

20090197324, Aug 6, 2009

Filed:

Apr 8, 2008

Appl. No.:

12/099725

Inventors:

Robert FISHMAN - Boston MA, US
Robert HAVENER - Lynnfield MA, US
Ihab Abdel FATTAH - Andover MA, US
Anas ABDELAZIM - North Andover MA, US
Scott NEWELL - Ipswich MA, US
Tom BISHOP - Wenham MA, US
Tamer KHAYAL - North Andover MA, US
Stanley KYI - Andover MA, US
Ron TAYLOR - Chester NH, US
Doug HARRIOTT - Melrose MA, US
Matthew DE REMER - Allston MA, US
Paul MURRAY - Groton MA, US
John SULLIVAN - Groton MA, US
Mark ANDERSON - Danvers MA, US
Richard BRINGHAM - North Andover MA, US
Michael VAN DRIEL - Mirandola, IT
Waleed Hassanein - , US

International Classification:

A01N 1/02

US Classification:

4352841

Abstract:

Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.

US Patent:

20090197325, Aug 6, 2009

Filed:

Apr 8, 2008

Appl. No.:

12/099728

Inventors:

Robert FISHMAN - Boston MA, US
Robert HAVENER - Lynnfield MA, US
Ihab Abdel FATTAH - Andover MA, US
Anas ABDELAZIM - North Andover MA, US
Scott NEWELL - Ipswich MA, US
Tom BISHOP - Wenham MA, US
Tamer KHAYAL - North Andover MA, US
Stanley KYI - Andover MA, US
Ron TAYLOR - Chester NH, US
Doug HARRIOTT - Melrose MA, US
Matthew DE REMER - Allston MA, US
Paul MURRAY - Groton MA, US
John SULLIVAN - Groton MA, US
Mark ANDERSON - Danvers MA, US
Richard BRINGHAM - North Andover MA, US
Michael VAN DRIEL - Mirandola, IT
Waleed Hassanein - , US

International Classification:

A01N 1/02

US Classification:

4352841

Abstract:

Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.