Paul Anthony Nelson

US Patent:

8394948, Mar 12, 2013

Filed:

Sep 28, 2010

Appl. No.:

12/891888

Inventors:

Paul S. Nelson - Morgan Hill CA, US
Hugh Mackie - Round Hill VA, US
Andrew Murphy - Brookeville MD, US

Assignee:

Glen Research Corporation - Sterling VA
Nelson Biotechnologies, Inc. - Morgan Hill CA

International Classification:

C07H 21/00
C07F 9/22

US Classification:

536 2532, 536 2534, 562 10

Abstract:

Novel CE-phosphoramidites and CPG reagents have been synthesized from a serinol backbone. These reagents are useful to introduce functional groups or directly label oligonucleotides. The versatile serinol scaffold allows for labeling at any position (5′ or 3′ termini, or any internal position) during automated DNA synthesis. Multiple labels or functional groups can be achieved by repetitive coupling cycles. Optimal spacer arms and protected label moieties have been specially designed. Further, the natural 3-carbon atom internucleotide phosphate distance is retained when inserted internally.

US Patent:

51913682, Mar 2, 1993

Filed:

Feb 18, 1992

Appl. No.:

7/836260

Inventors:

Kevin A. Kalua - Angwin CA
Paul A. Nelson - Angwin CA

International Classification:

G03B 2100

US Classification:

353 2

Abstract:

The present invention relates to a system for group viewing of kaleidoscopic images in which such system is a fully-integrated unit that is compact, attractive and of relatively low cost. In preferred form, the system uses a TEE-shaped outer housing in which system elements for the separate functions of cooling, for kaleidoscopically projection, for viewing and for angular pattern driving are accurately and compactly provided. The system elements that provide the functions of cooling, kaleidoscopic projection and viewing are positioned in first and second parallel arms (of circular cross section). While a third transverse arm (of square cross section attached to a flared base supported on a horizontal surface of a desk, table or the like, supports the angular driving elements.

US Patent:

50945254, Mar 10, 1992

Filed:

Aug 3, 1990

Appl. No.:

7/563097

Inventors:

Paul A. Nelson - Angwin CA

International Classification:

G03B 2100

US Classification:

353 1

Abstract:

The present invention relates to a projecting kaleidoscopic system for viewing kaleidoscopic images on a screen external of a conventional kaleidoscope. In one form, the system includes: (i) a high intensity lamp; (ii) a conventional kaleidoscope positioned in optical alignment with the lamp and including a tube of circular cross section having a longitudinal axis of symmetry, an eye piece at one end and an object box at an opposite end, the box including transparent wall means pointed at the lamp defining a cavity means filled with a multiplicity of loosely assorted pattern producing objects and reflector means within the tube between the eye piece and the transparent wall means wherein the tube, eye piece and object box provide a kaleidoscope that is a separately marketable unit product in and of itself; (iv) drive means mounted in frictional contact with the kaleidoscope for sole support thereof held in such contact by gravity alone wherein the kaleidoscope as a separately marketable unit can be evaluated, the drive means rotating the kaleidoscope about its axis of symmetry at relatively low RPM; (iv) optical lens and focusing means external of the kaleidoscope for optically receiving, enlarging and projecting the kaleidoscopic images appearing at the eye piece; and (v) a rear projection screen means external of the kaleidoscope for viewing the images whereby group viewing is enjoyed.