Paul Living Russell

US Patent:

6337431, Jan 8, 2002

Filed:

Oct 6, 1997

Appl. No.:

08/860379

Inventors:

David M Tricoli - Davis CA
Kim J. Carney - Davis CA
Paul F. Russell - Portage MI
Hector D. Quemada - Kalamazoo MI
Russell J. McMaster - Kenosha WI
John F. Reynolds - Davis CA
Rosaline Z. Deng - Oceanside CA

Assignee:

Seminis Vegetable Seeds, Inc. - Saticov CA

International Classification:

C12N 1582

US Classification:

800280, 4353201, 435419, 435468, 435469, 800288, 800301, 800294, 800317

Abstract:

The present invention provides a chimeric recombinant DNA molecule comprising: a plurality of DNA sequences, each of which comprises a plant-functional promoter linked to a coding region, which encodes a virus-associated coat protein, wherein said DNA sequences are preferably linked in tandem so that they are expressed in virus-susceptible plant cells transformed with said recombinant DNA molecule to impart resistance to said viruses; as well as methods for transforming plants with the chimeric recombinant DNA molecule and for selecting plants which express at least one of said DNA sequences imparting viral resistance.

US Patent:

20020059660, May 16, 2002

Filed:

Oct 9, 2001

Appl. No.:

09/974015

Inventors:

David Tricoli - Davis CA, US
Kim Carney - Davis CA, US
Paul Russell - Portage MI, US
Hector Quemada - Kalamazoo MI, US
J. McMaster - Kenosha WI, US
John Reynolds - Davis CA, US
Rosaline Deng - Oceanside CA, US

International Classification:

C12N015/82
A01H005/00
C12N015/87
C12N015/33
C12N015/84

US Classification:

800/280000, 800/294000, 800/307000, 800/308000, 800/309000, 800/310000, 800/301000, 536/023720

Abstract:

The present invention provides a chimeric recombinant DNA molecule comprising: a plurality of DNA sequences, each of which comprises a plant-functional promoter linked to a coding region, which encodes a virus-associated coat protein, wherein said DNA sequences are preferably linked in-tandem so that they are expressed in virus-susceptible plant cells transformed with said recombinant DNA molecule to impart resistance to said viruses; as well as methods for transforming plants with the chimeric constructs and for selecting plants which express at least one of said DNA sequences imparting viral resistance.

US Patent:

20130184318, Jul 18, 2013

Filed:

Apr 28, 2011

Appl. No.:

13/643543

Inventors:

Paul Russell - Davis CA, US
Christopher J. Murphy - Davis CA, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

C12Q 1/02

US Classification:

514369, 435 29, 548187, 435375, 435 612, 435 71

Abstract:

The present invention provides methods of determining the effect of test agents on the compliance of trabecular meshwork (TM) tissue, at the level of the extracellular matrix (ECM) and/or cells within the TM. Agents that modulate (e.g., increase or decrease) compliance of the TM tissue find use. Agents that increase the compliance of ECM and TM cells within the TM find use in the treatment and prevention of eye disorders characterized by high intraocular pressure, e.g., glaucoma.

US Patent:

20130211542, Aug 15, 2013

Filed:

Feb 7, 2013

Appl. No.:

13/762290

Inventors:

The Regents of the University of California - , US
Christopher J. Murphy - Davis CA, US
Paul Russell - Davis CA, US
Shaun P. Garland - Davis CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

A61F 2/02
B29C 59/02
B29C 35/08
B05D 3/10

US Classification:

623 2372, 427 21, 216 37, 264220, 264494

Abstract:

The present invention provide methods for preparing nanostructured membranes. The methods include: providing a substrate with a charged silanized surface; forming a multilayered membrane containing at least two polyelectrolytes; inducing polyelectrolyte phase separation; crosslinking the multilayered membrane; and covalently linking the multilayered membrane to the silanized surface. Methods for fabricating membrane replicas are also disclosed, as well as devices such as cell- and tissue-culture substrates that contain the membranes and membrane replicas. Resulting materials exhibit topographic features and compliance of the extracellular matrix in vivo.

US Patent:

60159421, Jan 18, 2000

Filed:

Oct 6, 1997

Appl. No.:

8/860543

Inventors:

David M Tricoli - Davis CA
Kim J. Carney - Davis CA
Paul F. Russell - Portage MI

Assignee:

Seminis Vegetable Seeds, Inc. - Saticoy CA

International Classification:

C12N 504
C12N 1533
C12N 1582
A01H 100

US Classification:

800280

Abstract:

A method for increasing virus resistance to a transgenic plant comprising a coat protein gene from a cucumber mosaic virus is provided.

US Patent:

60018534, Dec 14, 1999

Filed:

Jul 21, 1998

Appl. No.:

9/117068

Inventors:

J. Samuel Zigler - Middletown MD
Paul Russell - Bethesda MD
Santa Tumminia - Ellicott City MD
Chuan Qin - Somerville MA
C. Murali Krishna - Derwood MD

Assignee:

The United States of America as represented by the Department of Health
and Human Services - Washington DC

International Classification:

A61K 31445
A61K 3142

US Classification:

514315

Abstract:

A pharmaceutical composition and treatment to inhibit the development of cataracts in the crystalline lens of the eye by administering a hydroxylamine to a subject at risk of developing a cataract. The pharmaceutical composition comprises a hydroxylamine compound in a therapeutically sufficient amount to prevent or retard the development of the cataract. A reducing agent can also be administered in combination with the hydroxylamine. Particular examples of the hydroxylamine are TEMPOL-H, TEMPO-H and OXANO-H, while particular examples of the reducing agent are a sulfhydryl compound, such as N-(2-mercaptopropionyl)glycine (MPG), N-acetyl cysteine,. beta. -mercaptopropionyl glycine, and glutathione. In particular embodiments, the composition comprises TEMPOL-H in an amount that is sufficient to provide a concentration of about 1. mu. M to 1 mM in the aqueous humor of the eye, and mercaptopropionyl glycine in an amount sufficient to provide an aqueous humor concentrations of about 0. 1 to 5 mM.

US Patent:

20140199275, Jul 17, 2014

Filed:

May 31, 2012

Appl. No.:

14/119875

Inventors:

- Oakland CA, US
Paul Russell - Davis CA, US
Dori L. Borjesson - Davis CA, US
Joshua Wood - Vacaville CA, US

Assignee:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA

International Classification:

A61K 35/28
A61M 5/00

US Classification:

424 937, 604272

Abstract:

This invention provides methods of preventing, reducing or inhibiting one or more symptoms of a tear film disorder by administration to a subject mesenchymal stem cells.

Address:

3712 Bradley Ln, Chevy Chase, MD 20815

Phone:

3016560576

VIN:

5FPYK1F58BB007456

Make:

HONDA

Model:

RIDGELINE

Year:

2011