- Bethesda MD, US - Bellinzona, CH Tongqing Zhou - Boyds MD, US John Mascola - Rockville MD, US Kai Xu - Bethesda MD, US Yongping Yang - Potomac MD, US Paul Thomas - Washington DC, US Li Ou - Bethesda MD, US Peter Kwong - Washington DC, US Yaroslav Tsybovsky - Jefferson MD, US Wing-Pui Kong - Germantown MD, US Aliaksandr Druz - Germantown MD, US Davide Corti - Bellinzona, CH Antonio Lanzavecchia - Bellinzona, CH
Assignee:
The United States of America, as represented by the Secretary, Dept. of Health and Human Services - Bethesda MD Institute for Research in Biomedicine - Bellinzona
International Classification:
C07K 14/005 C12N 7/00 A61K 39/155 A61P 31/14
Abstract:
Embodiments of a recombinant human Parainfluenza Virus (hPIV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the hPIV F ectodomain trimer and methods of producing the hPIV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or inhibiting a hPIV infection in a subject by administering a effective amount of the recombinant hPIV F ectodomain trimer to the subject.
Self-Assembling Insect Ferritin Nanoparticles For Display Of Co-Assembled Trimeric Antigens
- Bethesda MD, US Ivelin Georgiev - Nashville TN, US Michael Gordon Joyce - Washington DC, US Masaru Kanekiyo - Chevy Chase MD, US Aliaksandr Druz - Germantown MD, US Ulrich Baxa - Frederick MD, US Joseph Van Galen - North Wales PA, US Rita Chen - Bethesda MD, US Cheng Cheng - Rockville MD, US John Mascola - Rockville MD, US Yaroslav Tsybovsky - Frederick MD, US Yongping Yang - Potomac MD, US Paul Thomas - Washington DC, US Barney Graham - Rockville MD, US Syed Mohammad Moin - Bethesda MD, US Jeffrey Boyington - Clarksburg MD, US Kizzmekia Corbett - Bethesda MD, US
Assignee:
The United States of America, as represented by the Secretary, Dept. of Health and Human Service - Bethesda MD
Disclosed are recombinant insect ferritin nanoparticles that can be used to display two different trimeric antigens at an equal ratio. Also disclosed are nucleic acids encoding the recombinant insect ferritin nanoparticles and methods of producing the recombinant insect ferritin nanoparticles. Methods for eliciting an immune response in a subject are also provided.
Substitutions-Modified Prefusion Rsv F Proteins And Their Use
- Bethesda MD, US Barney Graham - Rockville MD, US John Mascola - Rockville MD, US Li Ou - Potomac MD, US Aliaksandr Druz - Germantown MD, US Man Chen - Bethesda MD, US Wing-Pui Kong - Germantown MD, US Ivelin Stefanov Georgiev - Nashville TN, US Emily Rundlet - New York NY, US Michael Gordon Joyce - Washington DC, US Yaroslav Tsybovsky - Frederick MD, US Paul Thomas - Washington DC, US Marie Pancera - Seattle WA, US Mallika Sastry - Rockville MD, US Cinque Soto - Nashville TN, US Joseph Van Galen - North Wales PA, US Guillaume Stewart-Jones - Bethesda MD, US Yongping Yang - Potomac MD, US Baoshan Zhang - Bethesda MD, US Ulrich Baxa - Frederick MD, US
Assignee:
The United States of America, as represented by the Secretary, Department of Health and Human - Bethesda MD
International Classification:
C07K 14/005 A61P 31/14 A61P 37/04
Abstract:
Embodiments of a recombinant Respiratory Syncytial Virus (RSV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the RSV F ectodomain trimer and methods of producing the RSV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the recombinant RSV F ectodomain trimer to the subject.
Vanderbilt Medical GroupVanderbilt Bone & Joint Surgery Center 206 Bedford Way, Franklin, TN 37064 6155993883 (phone), 6157948845 (fax)
Education:
Medical School University of Tennessee College of Medicine at Memphis Graduated: 1983
Procedures:
Arthrocentesis Hallux Valgus Repair Hip Replacement Joint Arthroscopy Knee Arthroscopy Knee Replacement Lower Arm/Elbow/Wrist Fractures and Dislocations Lower Leg/Ankle Fractures and Dislocations Occupational Therapy Evaluation Shoulder Arthroscopy Shoulder Surgery Spinal Surgery Carpal Tunnel Decompression
Conditions:
Internal Derangement of Knee Cartilage Intervertebral Disc Degeneration Lateral Epicondylitis Osteoarthritis Rotator Cuff Syndrome and Allied Disorders
Languages:
English
Description:
Dr. Thomas graduated from the University of Tennessee College of Medicine at Memphis in 1983. He works in Franklin, TN and 1 other location and specializes in Orthopaedic Surgery. Dr. Thomas is affiliated with Vanderbilt University Medical Center and Williamson Medical Center.
Dr. Thomas graduated from the Dartmouth Medical School in 1985. He works in Portland, OR and specializes in Pediatrics. Dr. Thomas is affiliated with Providence Saint Vincent Medical Center.
Dr. Thomas graduated from the Texas Tech University Health Science Center School of Medicine - Lubbock in 1981. He works in McAlester, OK and specializes in Pediatrics and Pediatric Allergy/Immunology. Dr. Thomas is affiliated with McAlester Regional Health Center.
Dr. Thomas graduated from the A.T. Still University of Health Sciences/ Kirksville College of Osteopathic Medicine in 1994. He works in Euclid, OH and 1 other location and specializes in Family Medicine.
Dr. Thomas graduated from the Des Moines University College of Osteopathic Medicine in 1992. He works in Center Point, IA and specializes in Family Medicine. Dr. Thomas is affiliated with Mercy Hospital and St Lukes Hospital.
Twin Lakes Regional Medical Center ER 910 Wallace Ave, Leitchfield, KY 42754 2702599400 (phone), 2702599502 (fax)
Education:
Medical School University of Louisville School of Medicine Graduated: 1994
Languages:
English
Description:
Dr. Thomas graduated from the University of Louisville School of Medicine in 1994. He works in Leitchfield, KY and specializes in Emergency Medicine. Dr. Thomas is affiliated with Twin Lakes Regional Medical Center.
May 2011 to 2000 Project ManagerEnvironmental management specialists Middleburg Heights, OH Apr 2009 to Mar 2010 Project ManagerSunpro Inc. North Canton, OH Jan 2008 to Mar 2009 Hazardous waste coordinatorHubert's landscape Avon Lake, OH May 1999 to May 2001 Irrigation TechnicianLG Philips Ottawa, OH May 1999 to May 2001 Environmental EngineerThe Washington Center Washington, DC Jan 1993 to May 1993 Environmental lobbyist
Education:
Bowling Green State University Bowling Green, OH 1988 to 1993 Bachelor of Science in Environmental Policy and Analysis
Skills:
Proficient in Microsoft windows,windows XP professional Excel PowerPoint laboratory information management systems and Omega software
Jan 2012 to Jun 2014 DIRECTOR, MEDICAL OPERATIONSCovenant Health System
Aug 2010 to Jun 2011 HEALTHCARE STRATEGISTCorrectional Medical Services
Aug 2006 to Jun 2009 SENIOR REGIONAL MANAGERDepartment of Anesthesiology Lubbock, TX Sep 2001 to May 2005 SENIOR CLINICAL ADMINISTRATORTexas Tech University Health Sciences Center Lubbock, TX Sep 1999 to Sep 2001 HMO & HEALTH PLANS PROJECT ADMINISTRATORAmerica's Counseling Service, Inc Americus, GA Aug 1998 to Aug 1999 ADMINISTRATORSouthwest Georgia Healthcare Association, Inc Americus, GA Jul 1995 to Jun 1998 EXECUTIVE DIRECTORPROVIDER RELATIONS Richmond, VA May 1994 to May 1995 NETWORK DEVELOPMENTSupreme Headquarters Allied Powers Europe
Jul 1991 to Sep 1993 DEPUTY CHIEF, MEDICAL PLANS & OPERATIONSAir Force Surgeon General Washington, DC Jul 1987 to Jul 1991 CHIEF, HEALTH SERVICES OPERATIONSAmerican Hospital Association Washington, DC Jul 1986 to Jul 1987 SENIOR HEALTH POLICY FELLOWUnited States Air Force Hospital Blytheville, AR May 1983 to Jul 1986 HOSPITAL ADMINISTRATOR, CEOUS Air Force Hospital Reese Lubbock, TX May 1979 to Sep 1981 ASSISTANT ADMINISTRATOR, FINANCIAL OPERATIONSUS Air Force Hospital
Jan 1976 to Sep 1979 ASSISTANT ADMINISTRATOR, FINANCIAL OPERATIONSPATIENT AFFAIRS
Jan 1975 to Jan 1976 ASSISTANT ADMINISTRATORMED SERVICES SQUADRON
Jan 1974 to Jan 1976 ASSISTANT ADMINISTRATOR, MANAGER
Oct 2013 to 2000 Collaborations Technologies ConsultantTelespace LLC
2012 to 2013 Senior Architect Telepresence ServicesKBZ Communications
2009 to 2012 Director of Installation ServicesGoogle Mountainview, CA, US 2007 to 2009 Advanced Services Consultant Level 3now Cisco Reston, VA 2004 to 2007 Advanced Services EngineerMemphis Magic BBQ LLC Memphis, TN 2003 to 2004 Owner
Education:
Temple University 1990 Bachelor of Science in Electrical Engineering
Saint Louis University (SLU) St. Louis, MO Mar 2010 to Jan 2011 General CleanerMoores Food Distributors St. Louis, MO Feb 2009 to Aug 2010 Forklift Driver/Material HandlerBurgerKing St. Louis, MO Feb 2007 to Sep 2007 Prep/Line Cook
Sears Automotive Roseville, CA Aug 2014 to Oct 2014 Customer Service AdvisorSears Roseville, CA Jan 2014 to Aug 2014 Cashier/Sales AssociateBubba's BBQ North Highlands, CA Jan 2013 to Aug 2013 Crew Member/CashierRaley Field West Sacramento, CA Feb 2012 to Nov 2012 Clean TeamSim's Recycling Solutions Roseville, CA Jul 2010 to Dec 2010 Dis-Assembler
Education:
Yuba College Marysville, CA 2014 to 2016 SpeechSacramento City College Sacramento, CA 2010 to 2014 CommunicationsRiver Valley High School Yuba City, CA 2006 to 2010 High School Diploma
Skills:
Studio/Audio Production Engineer, Music Producer, Song Writer
Aug 2009 to 2000 Senior Manager of Aquatic Sciences, Facilities and ProjectsHouston Zoo Inc Houston, TX Nov 2007 to Aug 2009 Aquarist/Aquatic Life Support SpecialistSmithsonian National Zoological Park Washington, DC Feb 2006 to Oct 2007 HVAC-R/Life Support Supervisor/ManagerBeaver Valley
Mar 2004 to Feb 2006 Volunteer Zoo KeeperSiemens Building Technologies Inc Beltsville, MD Sep 2002 to Feb 2006 Union Steamfitter/ Life Support Technician
Education:
UA Mechanical Trade School Landover, MD 2003 to 2006 HVAC-R
CITIGROUP, Operations & Technology Financial Control
Jan 2005 to Present Financial Analyst for Citi Shared Services (CSS) Financial ControlCITIGROUP, Audit and Risk Review New York, NY Aug 2001 to Jan 2005 Financial/Project Analyst for Global Technology & InfrastructureVarious
Jan 2001 to May 2001 Executive Assistant to the Managing Director of Human ResourcesSCP COMMUNICATIONS New York, NY Sep 1999 to Oct 2000 Assistant to Program Manager
Education:
HOWARD UNIVERSITY Washington, DC May 1999 B.A. in Telecommunication Management
Oldcastle Materials Atlanta, GA 2013 to 2014 Sales and Business Development Manager, Memphis, TNPrairie Material Chicago, IL 2012 to 2013 Sales ManagerMartin Marietta Materials Raleigh, NC 2010 to 2012 District Sales Manager, Atlanta, GAOldcastle Materials Memphis, TN 2007 to 2010 Sales and Business Development ManagerOldcastle Materials Washington, DC 2006 to 2010Oldcastle Materials Kennesaw, GA 2007 to 2007 Vice-PresidentAPAC - TN's Brickey Memphis, TN 2006 to 2007 Sales and Business Development ManagerMartin Marietta Materials Memphis, TN 2005 to 2006 Area Sales ManagerMartin Marietta Materials Raleigh, NC 2004 to 2006Martin Marietta Materials Jackson, MS 2004 to 2005 Senior Sales RepresentativeAllied Custom Gypsum Alexandria, VA 2001 to 2003 Vice-PresidentGeorgia-Pacific Blue Rapids, KS 1999 to 2001 Plant ManagerGeorgia-Pacific Atlanta, GA 1987 to 2001Georgia-Pacific Atlanta, GA 1991 to 1999 National Sales Manager
Education:
Mississippi State University Starkville, MS 1981 to 1985 B.B.A. in Marketing
York, North Yorkshire, UKPM Practice Lead at Norwich Union Aviva UK Past: Lead Professional Development Manager at Norwich Union quite a varied career to-date:
Finance; Corporate Risk Management; broader governance; People Development & Coaching; Organisational Design; Learning &... quite a varied career to-date:
Finance; Corporate Risk Management; broader governance; People Development & Coaching; Organisational Design; Learning & Development.
Among the signers was Paul Thomas, an anti-vaccine doctor who voluntarily surrendered his medical license in 2022 after Oregons medical board found he had engaged in repeated and gross negligence in the practice of medicine.
no such caveats, which some public-health experts worry could cause problems if course corrections are needed down the line. For all we know, new variants could necessitate more frequent updates, or, if viral mutation slows, we might not even need annual shots, Paul Thomas, an immunologist at St. Jude Ch
Date: Sep 09, 2022
Category: More news
Source: Google
What Does ‘Protection’ against COVID Really Mean?
Still, more emphasis on T cell research is needed because, for all that has been demonstrated so far, few studies have directly proved that T cells are helping protect against COVID. We all think they are, but its actually very hard to show, says Paul Thomas, an immunologist at St. Jude Children
Date: May 19, 2022
Category: More news
Source: Google
Scientists pour cold water on ‘intriguing’ similarity between COVID-19 and 1918 flu
We did identify a subset of COVID-19 patients with the broadly upregulated array of cytokines, which is a hallmark of cytokine storm, said co-author Paul Thomas, Ph.D., a member of the St. Jude Department of Immunology. But, overall, the average person with COVID-19 c even patients with moderate-
Date: Nov 14, 2020
Category: More news
Source: Google
How Covid Sends Some Bodies to War With Themselves
Children, whose immune systems are immature and developing, have naturally high levels of interferons and other cytokines circulating in their bodies. Kids are just off the charts with inflammation without symptoms, says Paul Thomas, an immunologist at St. Jude Childrens Research Hospital in M
Date: Aug 11, 2020
Category: More news
Source: Google
In-home antibody test shows promise; recovering surgery patients at risk from coronavirus
in the lungs. New data appear to turn that theory on its head. In a new study, only 4% of the 71 patients with severe COVID-19 had a true cytokine storm, Paul Thomas of St. Jude's Children's Research Hospital and Ali Ellebedy of Washington University School of Medicine told Reuters in a joint email.
Date: Jun 01, 2020
Category: Health
Source: Google
Tiger Woods moves on to PGA Championship as Justin Thomas wins Bridgestone by four shots
Thomas was moved to tears as he won his first PGA Tour title with his grandparents, Paul and Phyllis, in attendance. Paul Thomas was a PGA professional. Also on hand were Thomas father, Mike, a PGA pro and his sons instructor, and mother, Jani.
Date: Aug 05, 2018
Category: Headlines
Source: Google
GOOD CHARLOTTE To Release 'Generation Rx' Album In September; 'Actual Pain' Video Available
September 14 via a newly minted global partnership between the band's MDDN label and BMG. The disc represents both a new chapter and full circle moment for the group brothers Joel (vocals) and Benji Madden (guitar, vocals), Billy Martin (guitar), Paul Thomas (bass) and Dean Butterworth (drums). P
Westerly Parkway Junior High School State College PA 1973-1974
Community:
Bob Crossley, Isabel Dorothy, Josephine Modesto, Victor Burgos
Googleplus
Paul Thomas
Lived:
Morton Grove, IL Chesapeake, Virginia Fairfax, VA Manassas, VA Champaign, IL
Work:
Northwestern University - Analytical Biochemist George Mason University University of Illinois
Education:
University of Illinois, George Mason University
Paul Thomas
Work:
Senate of Canada - Researcher (2006-2008) Cancer Research UK - Parliamentary Affairs Assistant (2008-2009) Parliamentary Internship Programme - Intern (2005-2006) North-South Institute - Intern (2005-2007)
Education:
University of Toronto - Political Science, Wilfrid Laurier University - Political Science, Carleton University - Political Science
Relationship:
Married
Paul Thomas
Work:
J.P. Morgan & Co. - Vice President (2009) Barclays Capital - Assistant Vice President (2008-2009) Lehman Brothers - Senior Analyst (2006-2008) AT&T - Senior Analyst / Architect (2003-2006)
Education:
Indian Institute of Technology Madras
Tagline:
Paul Thomas
Paul Thomas
Work:
Merthyr Valley Homes - Tenant board member (2012) Service Leavers Wales - Founder & Team member (2012)
Education:
Penydre comp - None
About:
Sufferer of post traumatic stress disorder & founder of service leavers wales , After experiencing life after active service and the horror of transition to civilian life I created a pro active sy...
Tagline:
Turning The Impossible In To Possible
Bragging Rights:
Climbed everest
Paul Thomas
Work:
Radford University - Assistant Professor of Religious Studies (2008)
Education:
University of Missouri–Kansas City - Religious Studies, University of Missouri–Kansas City - History, Park University - History, Longview Community College - Liberal Arts
Paul Thomas
Work:
Majoobi AS - VP Marketing Asia Pacific (2011) Web Ink Creative - Managing Director (2004)
Education:
Cabramatta High School
About:
I'm a street photographer living in Sydney, Australia ... I photograph interesting people, real life moments, animals and street scapes.
Tagline:
Managing Director of Web Ink Creative, Sydney, VP Marketing Asia Pacific for Majoobi AS, Norway.
Paul Thomas
Work:
Nottingham Emmanuel School - Academic Mentor (4) Lloyds TSB - Business Manager (1988-2009)
Education:
Ellis Guilford - O levels, High Pavement - A levels
About:
Lived in Nottingham all my life. Worked in a bank for 21 years before finally escaping. Now work in the maths departement of a local secondary school. Married with one daughter