Paula N Friedman

US Patent:

6350583, Feb 26, 2002

Filed:

May 8, 2000

Appl. No.:

09/566876

Inventors:

Maurice Cohen - Highland Park IL
Tracey L. Colpitts - Round Lake IL
Paula N. Friedman - Deerfield IL
Edward N. Granados - Vernon Hills IL
Michael R. Klass - Libertyville IL
John C. Russell - Pleasant Prairie WI
Stephen D. Stroupe - Libertyville IL

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

G01N 3353

US Classification:

435 71, 435 4, 435 721, 435 723, 435 792, 436512, 436536, 530350, 530385, 5303871, 5303877, 5303879, 5303881, 53038815, 5303891, 5303897

Abstract:

A set of contiguous and partially overlapping RNA sequences and polypeptides encoded thereby, designated as PS190 and transcribed from prostate tissue is described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the prostate, such as prostate cancer. Also provided are antibodies which specifically bind to PS190-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific PS190 polypeptide, which molecules are useful for the therapeutic treatment of prostate diseases, tumors or metastases.

US Patent:

6368792, Apr 9, 2002

Filed:

Mar 27, 1998

Appl. No.:

09/049698

Inventors:

Maurice Cohen - Highland Park IL
Tracey L. Colpitts - Round Lake IL
Paula N. Friedman - Deerfield IL
Mark Hayden - Ingleside IL
Michael R. Klass - Libertyville IL
John C. Russell - Kenosha WI
Stephen D. Stroupe - Libertyville IL

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

C12Q 168

US Classification:

435 6, 435 911, 4353201, 435325, 435352, 435363, 435366, 4352523, 536 231

Abstract:

A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as CS193 and transcribed from GI tract tissue, are described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the GI tract, such as GI tract cancer. Also provided are antibodies which specifically bind to CS193-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific CS193 polypeptide, which molecules are useful for the therapeutic treatment of GI tract diseases, tumors or metastases.

US Patent:

6391543, May 21, 2002

Filed:

Apr 23, 1998

Appl. No.:

09/065383

Inventors:

Maurice Cohen - Highland Park IL
Tracey L. Colpitts - Round Lake IL
Paula N. Friedman - Deerfield IL
Julian Gordon - Lake Bluff IL
Edward N. Granados - Vernon Hills IL
Steven C. Hodges - Buffalo Grove IL
Michael R. Klass - Libertyville IL
Jon D. Kratochvil - Kenosha WI
John C. Russell - Pleasant Prairie WI
Stephen D. Stroupe - Libertyville IL

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

C12Q 168

US Classification:

435 6, 4352402, 4353201, 536 231, 536 243, 536 2431, 536 2432, 536 2433

Abstract:

A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as PS118 and transcribed from prostate tissue, is described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the prostate, such as prostate cancer. Also provided are antibodies which specifically bind to PS118-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific PS118 polypeptide, which molecules are useful for the therapeutic treatment of prostate diseases, tumors or metastases.

US Patent:

6538119, Mar 25, 2003

Filed:

Nov 18, 1998

Appl. No.:

09/193881

Inventors:

Maurice Cohen - Highland Park IL
Tracey L. Colpitts - Round Lake IL
Paula N. Friedman - Deerfield IL
Edward N. Granados - Vernon Hills IL
Michael R. Klass - Libertyville IL
John C. Russell - Pleasant Prairie WI
Stephen D. Stroupe - Libertyville IL

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

C07H 2102

US Classification:

536 231, 435 691, 4353201, 530350

Abstract:

A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as BS249 and transcribed from breast tissue, is described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, in vivo imaging, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the breast, such as breast cancer. Also provided are antibodies which specifically bind to BS249-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific BS249 polypeptide, which molecules are useful for the therapeutic treatment of breast diseases, tumors or metastases.

US Patent:

6627414, Sep 30, 2003

Filed:

Mar 30, 1998

Appl. No.:

09/050516

Inventors:

Maurice Cohen - Highland Park IL
Tracey L. Colpitts - Round Lake IL
Paula N. Friedman - Deerfield IL
Julian Gordon - Lake Bluff IL
Edward N. Granados - Vernon Hills IL
Mark A. Hayden - Ingleside IL
Steven C. Hodges - Buffalo Grove IL
Michael R. Klass - Libertyville IL
Jon D. Kratochvil - Wildwood MO
John C. Russell - Pleasant Prairie WI
Stephen D. Stroupe - Libertyville IL

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

C12P 2106

US Classification:

435 691, 435 6, 4352523, 4353201, 435325, 536 235, 536 2431

Abstract:

A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as CS 198 and transcribed from GI tract tissue, is described. These sequences are useful for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the GI tract, such as GI tract cancer. Also provided are antibodies which specifically bind to CS 198-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific CS 198 polypeptide, which molecules are useful for the therapeutic treatment of GI tract diseases, tumors or metastases.

US Patent:

6660834, Dec 9, 2003

Filed:

Oct 23, 2002

Appl. No.:

10/278547

Inventors:

Maurice Cohen - Highland Park IL
Tracey L. Colpitts - Round Lake IL
Paula N. Friedman - Deerfield IL
Julian Gordon - Lake Bluff IL
Edward N. Granados - Vernon Hills IL
Mark A. Hayden - Ingleside IL
Steven C. Hodges - Buffalo Grove IL
Michael R. Klass - Libertyville IL
Jon D. Kratochvil - Wildwood MO
John C. Russell - Pleasant Prairie WI
Stephen D. Stroupe - Libertyville IL

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

C07K 1447

US Classification:

530324, 530350, 530828, 435810

Abstract:

A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as CS198 and transcribed from GI tract tissue, is described. These sequences are useful for detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the GI tract, such as GI tract cancer. Also provided are antibodies which specifically bind to CS198-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific CS198 polypeptide, which molecules are useful for the therapeutic treatment of GI tract diseases, tumors or metastases.

US Patent:

6770435, Aug 3, 2004

Filed:

Nov 1, 1999

Appl. No.:

09/431384

Inventors:

Maurice Cohen - Highland Park IL
Tracey L. Colpitts - Round Lake IL
Paula N. Friedman - Deerfield IL
Julian Gordon - Lake Bluff IL
Edward N. Granados - Vernon Hills IL
Steven C. Hodges - Buffalo Grove IL
Michael R. Klass - Libertyville IL
Jon D. Kratochvil - Wildwood MO
John C. Russell - Pleasant Prairie WI
Christi P. Scheffel - Mundelein IL
Stephen D. Stroupe - Libertyville IL

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

C12Q 168

US Classification:

435 6, 435 724, 435 94, 536 231, 536 243, 436501, 436504

Abstract:

A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as BU101 and transcribed from breast tissue, is described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, in vivo imaging, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the breast, such as breast cancer. Also provided are antibodies which specifically bind to BU101-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific BU101 polypeptide, which molecules are useful for the therapeutic treatment of breast diseases, tumors or metastases.

US Patent:

6867016, Mar 15, 2005

Filed:

Mar 31, 1998

Appl. No.:

09/052855

Inventors:

Maurice Cohen - Highland Park IL, US
Tracey L. Colpitts - Round Lake IL, US
Paula N. Friedman - Deerfield IL, US
Julian Gordon - Lake Bluff IL, US
Edward N. Granados - Vernon Hills IL, US
Mark A. Hayden - Ingleside IL, US
Steven C. Hodges - Buffalo Grove IL, US
Michael R. Klass - Libertyville IL, US
Jon D. Kratochvil - Wildwood MO, US
John C. Russell - Pleasant Prairie WI, US
Stephen D. Stroupe - Libertyville IL, US

Assignee:

Abbott Laboratories - Abbott Park IL

International Classification:

C12N005/10
C12N015/00
C07H021/04

US Classification:

435 691, 4353201, 435325, 4352523, 43525411, 536 235

Abstract:

A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as CS141 and transcribed from GI tract tissue, is described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the GI tract, such as GI tract cancer. Also provided are antibodies which specifically bind to CS141-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific CS141 polypeptide, which molecules are useful for the therapeutic treatment of GI tract diseases, tumors or metastases.