Alison G. Floyd - Durham NC, US Mir A Hashim - Durham NC, US Peiyuan Lin - Durham NC, US Robert A. Mook - Durham NC, US Andrea Sefler - Durham NC, US Kathleen Cornell Meserve - Durham NC, US Patricia Neal Ricciarelli - Durham NC, US Timothy David Spitzer - Durham NC, US
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
A61K031/47 A61K031/165
US Classification:
514308, 424 44
Abstract:
The invention relates to pharmaceutical formulations and methods for preparing pharmaceutical formulations of histamine releasers. The present invention provides methods for determining the concentration of physiologically acceptable excipients for use in the formulations of the invention. The present invention also provides methods for suppressing pharmaceutically-induced histamine release by administering to an animal, the formulations of the present invention. A kit useful for preparing pharmaceutical formulations of histamine releasers is also provided.
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