- Santa Monica CA, US Faisal Hayat MALIK - Cerritos CA, US Josh SNYDER - Santa Monica CA, US Leslie Renee BUTTERWORTH - Kirkland WA, US Ssucheng Jeff HSU - Pinole CA, US Peng YANG - Los Angeles CA, US Claudia Isabel GUEVARA - South Gate CA, US
Assignee:
AGENSYS, INC. - Santa Monica CA
International Classification:
A61K 47/68 A61K 45/06
Abstract:
Antibody drug conjugates (ADC's) that bind to CD37 protein and variants thereof are described herein. CD37 exhibits a distinct and limited expression pattern in normal adult tissue(s), and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention in some embodiments provide a therapeutic composition for the treatment of cancer.
Nectin-4 Binding Proteins And Methods Of Use Thereof
- Santa Monica CA, US Fernando DONATE - Santa Monica CA, US Peng YANG - Santa Monica CA, US
Assignee:
AGENSYS, INC. - Santa Monica CA
International Classification:
C07K 16/28 G01N 33/574
Abstract:
Provided herein are compositions, methods and uses involving antibodies that specifically bind to Nectin-4. Also provided herein are methods for assessing Nectin-4 expression in a sample or a patient and methods for assessing responsiveness of a cancer patient to an anti-cancer therapeutic agent.
Antibody Drug Conjugates (Adc) That Bind To Cd37 Proteins
- Santa Monica CA, US Faisal Hayat MALIK - Cerritos CA, US Josh SNYDER - Santa Monica CA, US Leslie Renee BUTTERWORTH - Kirkland WA, US Ssucheng Jeff HSU - Pinole CA, US Peng YANG - Los Angeles CA, US Claudia Isabel GUEVARA - South Gate CA, US
International Classification:
A61K 47/68 A61K 45/06
Abstract:
Antibody drug conjugates (ADC's) that bind to CD37 protein and variants thereof are described herein. CD37 exhibits a distinct and limited expression pattern in normal adult tissue(s), and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention in some embodiments provide a therapeutic composition for the treatment of cancer.
Antibody Drug Conjugates (Adc) That Bind To Cd37 Proteins
- Santa Monica CA, US Faisil Hayat MALIK - Cerritos CA, US Josh SNYDER - Santa Monica CA, US Leslie Renee BUTTERWORTH - Kirkland WA, US Ssucheng Jeff HSU - Pinole CA, US Peng YANG - Los Angeles CA, US Claudia Isabel GUEVARA - South Gate CA, US
International Classification:
A61K 47/48 A61K 45/06
Abstract:
Antibody drug conjugates (ADC's) that bind to CD37 protein and variants thereof are described herein. CD37 exhibits a distinct and limited expression pattern in normal adult tissue(s), and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention in some embodiments provide a therapeutic composition for the treatment of cancer.
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