G. K. Surya Prakash - Hacienda Heights CA, US Mian M. Alauddin - Alhambra CA, US Jinbo Hu - Los Angeles CA, US Peter S. Conti - Pasadena CA, US George A. Olah - Beverly Hills CA, US
Assignee:
University of Southern California - Los Angeles CA
International Classification:
C07C045/00 G21G001/06 G06K009/00
US Classification:
568323, 568325, 376168, 382130, 382131
Abstract:
The present invention is directed to a convenient method of synthesizing radiolabeled α-trifluoromethyl ketones by a fluorination reaction. The present invention also relates to imaging agents and markers for identifying cell proliferation, or viral infection. The markers and imaging agents including the radiolabeled α-trifluoromethyl ketones that are prepared by the present method.
[18F]-Furanosylpurine Derivatives And Uses Thereof
Peter S. Conti - Pasadena CA, US Mian M. Alauddin - Alhambra CA, US John D. Fissekis - South Pasadena CA, US
Assignee:
University of Southern California - Los Angeles CA
International Classification:
A61K 51/00 A61M 36/14
US Classification:
424 111
Abstract:
2′-Deoxy-2′-[F]-labeled and 3′-deoxy-3′-[F]-labeled purine nucleoside analogs such as [F]-FAA and [F]-FXA have been found to have desirable properties for use as imaging agents. The analogs are particularly useful for in vivo imaging of biological material including organ tissues (e. g. , heart, liver, brain and kidneys) and tumors. Methods for the preparation of the [F]-FAA and [F]-FXA are also provided.
[18F]-Furanosylpurine Derivatives And Uses Thereof
Peter S. Conti - Pasadena CA, US Mian M. Alauddin - Alhambra CA, US John D. Fissekis - South Pasadena CA, US
Assignee:
University of Southern California - Los Angeles CA
International Classification:
A61K 51/00 A61M 36/14
US Classification:
424 111, 424 189
Abstract:
2′-Deoxy-2′-[F]-labeled and 3′-deoxy-3′-[F]-labeled purine nucleoside analogs such as [F]-FAA and [F]-FXA have been found to have desirable properties for use as imaging agents. The analogs are particularly useful for in vivo imaging of biological material including organ tissues (e. g. , heart, liver, brain and kidneys) and tumors. Methods for the preparation of the [F]-FAA and [F]-FXA are also provided.
Cage-Like Bifunctional Chelators, Copper-64 Radiopharmaceuticals And Pet Imaging Using The Same
Disclosed is a class of versatile Sarcophagine based bifunctional chelators (BFCs) containing a hexa-aza cage for labeling with metals having either imaging, therapeutic or contrast applications radiolabeling and one or more linkers (A) and (B). The compounds have the general formula
Boron-Based Dual Imaging Probes, Compositions And Methods For Rapid Aqueous F-18 Labeling, And Imaging Methods Using Same
Zibo LI - San Gabriel CA, US Francois P. GABBAI - College Station TX, US Peter S. CONTI - Pasadena CA, US Todd W. HUDNALL - College Station TX, US Tzu-Pin LIN - College Station TX, US Shuanglong LIU - Alhambra CA, US
Assignee:
UNIVERSITY OF SOUTHERN CALIFORNIA - Los Angeles CA
International Classification:
A61K 51/04 C07F 5/02
US Classification:
424 165, 548405, 424 96, 530331, 530317
Abstract:
A composition useful as a PET and/or fluorescence imaging probe a compound a compound of Formula I, including salts, hydrates and solvates thereof:
Methods And Compositions For The Rapid Synthesis Of Radiometal-Labeled Probes
University of Southern California - Los Angeles CA
International Classification:
C07K 7/64
US Classification:
530321, 540476, 534 10
Abstract:
The present application is directed to rapid and efficient synthesis of radiometal-labeled probes, pharmaceutical compositions comprising radiometal-labeled probes, and methods of using the radiometal-labeled probes. Such radiometal-labeled probes can be used in imaging studies, such as Positron Emitting Tomography (PET) or Single Photon Emission Computed Tomography (SPECT), and therapy studies.
Peter S. Conti - Pasadena CA Mian M. Alauddin - Alhambra CA John D. Fissekis - South Pasadena CA
Assignee:
University Advanced Bio-imaging Associates - Los Angeles CA
International Classification:
A61K 5100 A61M 3614
US Classification:
424 189
Abstract:
The nucleoside analog 2'-fluoro-5-methyl-1-. beta. -D-arabinofuranosyluracil (FMAU) has been found to have an especially desirable combination of properties for use as an imaging agent, including in particular limited in vivo catabolism. Methods for the preparation of the [. sup. 11 C]-and [. sup. 18 F]-labeled FMAU and for the use of the labeled material are also provided.
Imaging Agents And Methods For The Preparation And Use Thereof
Peter S. Conti - Pasadena CA Mian M. Alauddin - Alhambra CA John D. Fissekis - South Pasadena CA
Assignee:
University Advanced Bio-Imaging Associates - Los Angeles CA
International Classification:
A61K 5100 A61M 3614
US Classification:
424 181
Abstract:
The nucleoside analog 2'-fluoro-5-methyl-1-. beta. -D-arabinofuranosyluracil (FMAU) has been found to have an especially desirable combination of properties for use as an imaging agent, including in particular limited in vivo catabolism. Methods for the preparation of the �. sup. 11 C!-labelled FMAU and for the use of the labelled material are also provided.
Medicine Doctors
Dr. Peter S Conti, Los Angeles CA - MD (Doctor of Medicine)
Keck Medical Center Of USC Radiology 1500 San Pablo St, Los Angeles, CA 90033 6264575830 (phone), 6264575851 (fax)
USC Pet Imaging Science Center 1510 San Pablo St STE 350, Los Angeles, CA 90033 3234425940 (phone), 3238659304 (fax)
Keck Medical Center Of USC Radiology 1520 San Pablo St STE L1600, Los Angeles, CA 90033 3234427450 (phone), 3238659519 (fax)
Education:
Medical School Cornell University Weill Medical College Graduated: 1985
Languages:
Chinese English Korean Spanish Vietnamese
Description:
Dr. Conti graduated from the Cornell University Weill Medical College in 1985. He works in Los Angeles, CA and 2 other locations and specializes in Diagnostic Radiology and Nuclear Medicine. Dr. Conti is affiliated with Keck Medical Center Of USC and USC Norris Cancer Hospital.
Nuclear Medicine Radiology Diagnostic Radiology Nuclear Radiology Public Health & General Preventive Medicine Bariatric Medicine
Work:
University of Southern California
1510 San Pablo St, Los Angeles, CA 90033 Healthcare Consultation Center
1000 S Fremont Ave, Alhambra, CA 91803 USC Care Medical Group Inc.
1500 San Pablo St, Los Angeles, CA 90033
1441 Eastlake Ave, Los Angeles, CA 90089 1510 San Pablo St, Los Angeles, CA 90033 1520 San Pablo St, Los Angeles, CA 90033
Education:
Cornell University, Weill Cornell Medical College - Doctor of Medicine Cornell University - Doctor of Philosophy Johns Hopkins Hospital - Residency - Radiology
Board certifications:
American Board of Nuclear Medicine Certification in Nuclear Medicine American Board of Radiology Certification in Diagnostic Radiology (Radiology)