Peter R Hanson

US Patent:

20200206166, Jul 2, 2020

Filed:

Jul 20, 2018

Appl. No.:

16/631277

Inventors:

- Boston MA, US
Peter D. Hanson - Bristol WI, US
Gary F. Musso - Hopkinton MA, US
Drazen Ostovic - Redwood City CA, US
Randall Stevens - Rockport MA, US

International Classification:

A61K 31/167
A61P 19/02
A61K 9/00
A61F 7/10

Abstract:

The invention provides methods and compositions for treatment of pain, such as joint pain, using capsaicin in a procedure that attenuates transient burning sensation experienced by patients due to capsaicin administration. The methods desirably provide relief from joint pain, such as osteoarthritic knee joint pain, for an extended duration, such as at least about 3 months, 6 months, 9 months, or 1 year. To attenuate the adverse side effect of a transient burning sensation caused by capsaicin-induced neuronal excitation, the methods utilize a cooling article, such as a material wrap cooled via a circulating fluid, to reduce the temperature of tissue to be exposed to capsaicin to within a certain range for certain durations of time, optionally in combination with administering a local anesthetic agent, resulting in the substantial reduction or even elimination of transient burning sensation caused by capsaicin.

US Patent:

20190022036, Jan 24, 2019

Filed:

Jan 20, 2017

Appl. No.:

16/070889

Inventors:

- Boston MA, US
Peter D. Hanson - Bristol WI, US
Randall Stevens - Rockport MA, US

International Classification:

A61K 31/165
A61P 29/02
A61K 47/10
A61K 9/00

Abstract:

A method of ameliorating pain for a duration of at least 3 months due to an intermetatarsal neuroma in a patient, comprising administering by injection into or adjacent to the patient's intermetatarsal space having an intermetatarsal neuroma at least a first dose of capsaicin and a second dose of capsaicin, no sooner than one month after the first dose, to ameliorate pain due to the intermetatarsal neuroma.

US Patent:

20180311189, Nov 1, 2018

Filed:

Nov 13, 2015

Appl. No.:

15/524843

Inventors:

- Boston MA, US
Peter D. Hanson - Bristol WI, US

International Classification:

A61K 31/165
A61K 9/00
A61P 17/00

Abstract:

The invention provides methods for treating acral lick granuloma in a canine using a capsaicinoid, such as capsaicin. The invention also provides methods for deactivating a nerve fiber selected from the group consisting of a C-fiber and an A-delta fiber, each being located in or proximal to an acral lick granuloma in a canine, using a capsaicinoid, such as capsaicin.