Peter S Kofinas

US Patent:

7063918, Jun 20, 2006

Filed:

Oct 22, 2001

Appl. No.:

10/380697

Inventors:

Peter Kofinas - North Bethesda MD, US
Steven Bullock - Silver Spring MD, US

Assignee:

The University of Maryland, College Park - College Park MD

International Classification:

H01M 4/60
H01M 10/40

US Classification:

429317, 429213, 429303

Abstract:

The present invention relates to a unique polymeric battery system of electrochemical cells that are connected in series, and can be of nanometer size. The polymers possess conjugated bonds along their backbones and high levels of metals. The invention also concerns methods for the fabrication of the polymers and battery system as well as methods for the use of the polymers as a nanoscale solid-state battery.

US Patent:

8138289, Mar 20, 2012

Filed:

Mar 14, 2008

Appl. No.:

12/048995

Inventors:

Peter Kofinas - North Bethesda MD, US
Daniel Janiak - Bethesda MD, US

Assignee:

University of Maryland, College Park - College Park MD

International Classification:

C08F 20/00

US Classification:

5263031, 264220, 264221, 264222

Abstract:

Imprinted polymeric materials that selectively bind to a template article. Various types of template articles may be targeted by the imprinted polymeric materials, including microorganisms (e. g. , viruses or bacteria) or biologic macromolecules (e. g. , proteins or DNA). The imprinted polymeric material may be formed by template-directed synthesis using monomer units that interact with the template article. The monomer units are used to form a polymer matrix around the template article. Subsequently, the template article is removed from the polymer matrix. Also disclosed are imprinted polymeric materials comprising a cross-linked polymer matrix, which comprises a polyampholyte polymer. The polymer matrix has a binding cavity capable of selectively binding to a template article. Also disclosed are various uses for such imprinted polymeric materials.

US Patent:

20040238783, Dec 2, 2004

Filed:

Jun 30, 2003

Appl. No.:

10/250433

Inventors:

Steven Bullock - Silver Spring MD, US
Sufi Ahmed - Silver Spring MD, US
Peter Kofinas - Bethesda MD, US

International Classification:

H01F001/00
H01F001/26
C04B035/04

US Classification:

252/062540

Abstract:

A method of room temperature synthesis of magnetic metal oxide nanoclusters within a diblock copolymer matrix includes the step of synthesizing, by ring opening metathesis polymerization technique, a diblock copolymer having a repeat unit ratio m/n, introducing, at room temperature, one or several metal containing precursors into the one block of the diblock copolymer, and processing the metal containing diblock copolymer by wet chemical technique to form nanoclusters of the metal(s) oxide within the diblock copolymer matrix. Specific reaction for synthesis of CoFeOand CoOnanoclusters within diblock copolymers, such as [NOR]/[NORCOOH]and [NOR]/[CO(bTAN)], respectively is used in the method of the present invention.

US Patent:

20100255383, Oct 7, 2010

Filed:

Mar 1, 2010

Appl. No.:

12/715178

Inventors:

Peter Kofinas - North Bethesda MD, US
Ayan Ghosh - Hyattsville MD, US

Assignee:

University of Maryland, College Park - College Park MD

International Classification:

H01M 6/18

US Classification:

429317, 429322, 429323

Abstract:

A flexible polymer solid electrolyte material useful in battery technology is described. The flexible solid electrolyte comprises a first block that has the ability to solvate alkali metal salts. The flexible solid electrolyte comprises a second block that has the ability to incorporate lithium ions within microphase separated spherical domains, wherein the lithium ions are from a secondary lithium source. The flexible solid electrolyte further comprises a second lithium salt.

US Patent:

20120009242, Jan 12, 2012

Filed:

Nov 3, 2009

Appl. No.:

13/127152

Inventors:

Brendan J. Casey - College Park MD, US
Peter Kofinas - North Bethesda MD, US
Adam Behrens - Olney MD, US
Trevor A. Snyder - Edmond OK, US
Bartley P. Griffith - Gibson Island MD, US

Assignee:

UNIVERSITY OF MARYLAND, COLLEGE PARK - College Park MD
UNIVERSITY OF MARYLAND, BALTIMORE - Baltimore MD

International Classification:

A61K 31/785
A61L 15/24
A61P 7/04
A61L 15/44
A61L 31/12
A61L 31/16
C08F 226/02
A61L 15/58

US Classification:

424446, 526307, 424 7835, 424447, 424445, 424400

Abstract:

The present application is drawn to a synthetic, polymer hydrogel-based material, which is able to actively induce the body's natural hemostatic coagulation process in blood or acellular plasma. The present invention provides the development of a primary amine containing polymer hydrogel capable of inducing blood coagulation and delivering therapeutics for hemostatic or wound care applications, and a method of forming such a primary amine containing polymer hydrogel capable of inducing the blood coagulation process. The primary amine containing polymer hydrogel is able to achieve the same end result as biological-based hemostatics, without the innate risk of disease transmission or immunological response, and at a fraction of the price. Furthermore, due to its inherent hydrogel-based design the material has the capability of arresting blood loss while simultaneously delivering therapeutics in a controlled manner, potentially revolutionizing the way in which wounds are treated.

US Patent:

20120309047, Dec 6, 2012

Filed:

May 31, 2012

Appl. No.:

13/484533

Inventors:

Peter Kofinas - North Bethesda MD, US
Omar B. Ayyub - Potomac MD, US
Jennifer W. Sekowski - Aberdeen MD, US
Ta-I Yang - Taichung, TW

Assignee:

University of Maryland, College Park - College Park MD

International Classification:

C08F 226/06
G01N 21/25

US Classification:

435 34, 525280, 436164, 436 94, 436 95, 436110, 436135, 436501

Abstract:

A sensor system, and a method of detecting a target analyte, comprises a chemically functionalized block copolymer, and a target analyte. The block copolymer exhibits a color change in the visible spectrum upon exposure to the target analyte.

US Patent:

20180143210, May 24, 2018

Filed:

Apr 27, 2016

Appl. No.:

15/570269

Inventors:

- College Park MD, US
- Washington DC, US
Peter Kofinas - North Bethesda MD, US
Gary Cunningham - Washington DC, US

Assignee:

University of Maryland, College Park - College Park MD
CHILDREN'S NATIONAL MEDICAL CENTER - Washington DC

International Classification:

G01N 33/84
B01L 3/00
G01N 21/78
A61K 31/216
A61P 3/00

Abstract:

The present disclosure relates to a biosensor capable of measuring the total concentration of one or a plurality of ammonia or ammonium ions with the use of indophenol reagents in the presence of an ionomer. In some embodiments, the biosensor comprises a perflurinated membrane that comprises an ionomer in contact with an alkali buffer in a vessel configured to receive a sample, such as whole blood. The disclosure also relates to a method of detecting or quantifying the ammonia or ammonium ion concentration in whole blood in a point of care bio sensor without reliance on gas chromatography or any measurement that takes more than about twenty minutes.

US Patent:

20170198329, Jul 13, 2017

Filed:

Apr 17, 2015

Appl. No.:

15/304852

Inventors:

- College Park MD, US
- District of Columbia DC, US
Peter KOFINAS - North Bethesda MD, US
Marshall Lynn SUMMAR - Washington, D.C. DC, US
Gary Cunningham - Washington, D.C., US

Assignee:

University of Maryland, College Park - College Park MD

International Classification:

C12Q 1/00
G01N 33/68
B01L 3/00
C12Q 1/32

Abstract:

The present disclosure relates to a biosensor capable of measuring the total concentration of one or a plurality of amino acids with the use of a reaction surface comprising one or a plurality of metabolic enzymes or functional fragments thereof, but wherein the reaction surface does not comprise an electrode or electrically conductive support. In some embodiments, the biosensor comprises use of a thermophilic bacterial metabolic enzyme immobilized or attached to the reaction surface.