Peter M Nelson

US Patent:

6849713, Feb 1, 2005

Filed:

Jun 26, 2001

Appl. No.:

09/892327

Inventors:

Wentao Zhang - Foster City CA, US
Sebastian Johannes Reinhard Liehr - East Palo Alto CA, US
Mark Douglas Velligan - Montara CA, US
Natalia B. Dyatkina - Mountain View CA, US
Janos Botyanszki - Cupertino CA, US
Dong-Fang Shi - San Mateo CA, US
Christopher Don Roberts - Belmont CA, US
Alexander Khorlin - Mountain View CA, US
Peter Harold Nelson - Los Altos CA, US
Joseph Martin Muchowski - Sunnyvale CA, US

Assignee:

Genelabs Technologies, Inc. - Redwood City CA

International Classification:

A61K 3804

US Classification:

530330

Abstract:

The present invention provides novel compounds possessing one or more of the following activities: antibacterial, antifungal and antitumor activity. The compounds are of Formula (I): Pharmaceutical compositions containing these compounds, methods of making and methods for using these compounds are also provided.

US Patent:

6906103, Jun 14, 2005

Filed:

Oct 23, 2002

Appl. No.:

10/277666

Inventors:

Wentao Zhang - Foster City CA, US
Sebastian Johannes Reinhard Liehr - East Palo Alto CA, US
Mark Douglas Velligan - Montara CA, US
Natalia B. Dyatkina - Mountain View CA, US
Janos Botyanszki - Cupertino CA, US
Dong-Fang Shi - San Mateo CA, US
Christopher Don Roberts - Belmont CA, US
Alexander Khorlin - Mountain View CA, US
Peter Harold Nelson - Los Altos CA, US
Joseph Martin Muchowski - Sunnyvale CA, US

Assignee:

Genelabs Technologies, Inc. - Redwood City CA

International Classification:

A61K031/13

US Classification:

514579

Abstract:

The present invention provides novel compounds possessing one or more of the following activities: antibacterial, antifungal and antitumor activity. The compounds are of Formula (I): Pharmaceutical compositions containing these compounds, methods of making and methods for using these compounds are also provided.

US Patent:

7432261, Oct 7, 2008

Filed:

Apr 26, 2004

Appl. No.:

10/833294

Inventors:

Carina Cannizzaro - San Mateo CA, US
James Chen - San Ramon CA, US
Xiaowu Chen - San Mateo CA, US
Aesop Cho - Mountain View CA, US
Lee Chong - Newark CA, US
Maria Fardis - San Carlos CA, US
Craig Gibbs - Palo Alto CA, US
Ralph F. Hirschmann - Philadelphia PA, US
Thorsten Kirschberg - Belmont CA, US
Christopher P. Lee - San Francisco CA, US
Kuei-Ying Lin - Fremont CA, US
Richard L. Mackman - Millbrae CA, US
Peter H. Nelson - Los Altos CA, US
David A. Oare - Belmont CA, US
Hyung-Jung Pyun - Freemont CA, US
Adrian S. Ray - San Mateo CA, US
Rosemarie Sherlock - Palo Alto CA, US
Sundaramoorthi Swaminathan - Burlingame CA, US
William J. Watkins - Sunnyvale CA, US
Jennifer R. Zhang - Foster City CA, US

Assignee:

Gilead Sciences, Inc. - Foster City CA

International Classification:

A61K 31/60
C07D 237/00

US Classification:

514247, 544224

Abstract:

The invention is related to phosphorus substituted anti-inflammatory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

US Patent:

7452901, Nov 18, 2008

Filed:

Apr 26, 2004

Appl. No.:

10/833293

Inventors:

Constantine G. Boojamra - San Francisco CA, US
Carina Cannizzaro - San Mateo CA, US
James M. Chen - San Ramon CA, US
Xiaowu Chen - San Mateo CA, US
Aesop Cho - Mountain View CA, US
Lee S. Chong - Newark CA, US
Maria Fardis - San Carlos CA, US
Alan X. Huang - San Mateo CA, US
Choung U. Kim - San Carlos CA, US
Thorsten Kirschberg - Belmont CA, US
Steven Krawczyk - San Carlos CA, US
Christopher P. Lee - San Francisco CA, US
Kuei-Ying Lin - Fremont CA, US
Richard L. Mackman - Millbrae CA, US
David Y. Markevitch - Los Angeles CA, US
Peter H. Nelson - Los Altos CA, US
David A. Oare - Belmont CA, US
Vidya K. Prasad - Burlingame CA, US
Hyung-Jung Pyun - Freemont CA, US
Adrian S. Ray - San Mateo CA, US
Sundaramoorthi Swaminathan - Burlingame CA, US
William J. Watkins - Sunnyvale CA, US
Jennifer R. Zhang - Foster City CA, US
Lijun Zhang - Palo Alto CA, US

Assignee:

Gilead Sciences, Inc. - Foster City CA

International Classification:

A61K 31/44
C07D 239/00

US Classification:

514300, 544300

Abstract:

The invention is related to phosphorus substituted anti-cancer compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

US Patent:

7462608, Dec 9, 2008

Filed:

Apr 25, 2003

Appl. No.:

10/424130

Inventors:

James M. Chen - San Ramon CA, US
Xiaowu Chen - San Mateo CA, US
Choung U. Kim - San Carlos CA, US
William A. Lee - Los Altos CA, US
Christopher P. Lee - San Francisco CA, US
Peter H. Nelson - Los Altos CA, US
James D. Tario - San Mateo CA, US
Lianhong Xu - San Mateo CA, US

Assignee:

Gilead Sciences, Inc. - Foster City CA

International Classification:

A61K 31/665
C07D 265/18

US Classification:

514 75, 544 90

Abstract:

Phosphorus-substituted imidazole compounds with anti-HIV properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit reverse transcriptase activity and are useful therapeutically for the inhibition of such enzymes, as well as in assays for the detection of such enzymes.

US Patent:

7462721, Dec 9, 2008

Filed:

Sep 17, 2004

Appl. No.:

10/944118

Inventors:

Haolun Jin - Foster City CA, US
Choung U. Kim - San Carlos CA, US
Peter H. Nelson - Los Altos CA, US

Assignee:

Gilead Sciences, Inc. - Foster City CA

International Classification:

C07J 1/00
C07D 471/02

US Classification:

546118, 546 9, 546123

Abstract:

Aza-quinolinol phosphonate compounds and methods for inhibition of HIV-integrase are disclosed. Ar is aryl or heteroaryl connecting Rto L. L is a bond or a linker connecting a ring atom of Ar to N. The ring atoms, X-Xmay be N, substituted nitrogen, or substituted carbon, and form rings. The compounds include at least one phosphonate group covalently attached at any site.

US Patent:

7470724, Dec 30, 2008

Filed:

Apr 26, 2004

Appl. No.:

10/833295

Inventors:

Carina Cannizzaro - San Mateo CA, US
James M. Chen - San Ramon CA, US
Xiaowu Chen - San Mateo CA, US
Aesop Cho - Mountain View CA, US
Lee S. Chong - Newark CA, US
Manoj Desai - Pleasant Hill CA, US
Maria Fardis - San Carlos CA, US
Alan X. Huang - San Mateo CA, US
Thorsten Kirschberg - Belmont CA, US
Christopher P. Lee - San Francisco CA, US
Richard L. Mackman - Millbrae CA, US
Peter H. Nelson - Los Altos CA, US
Hyung-Jung Pyun - Freemont CA, US
Adrian S. Ray - San Mateo CA, US
William J. Watkins - Sunnyvale CA, US
Jennifer R. Zhang - Foster City CA, US
Sundaramoorthi Swaminathan - Burlingame CA, US

Assignee:

Gilead Sciences, Inc. - Foster City CA

International Classification:

A61K 31/27

US Classification:

514470, 549462

Abstract:

The invention is related to phosphonate substituted compounds having immuno-modulatory activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

US Patent:

7645747, Jan 12, 2010

Filed:

Oct 25, 2005

Appl. No.:

11/258621

Inventors:

Constantine G. Boojamra - San Francisco CA, US
Carina E. Cannizzaro - Foster City CA, US
James M. Chen - San Ramon CA, US
Xiaowu Chen - San Mateo CA, US
Aesop Cho - Mountain View CA, US
Lee S. Chong - Newark CA, US
Manoj Desai - Pleasant Hill CA, US
Maria Fardis - San Carlos CA, US
Craig S. Gibbs - Palo Alto CA, US
Ralph F. Hirschmann - Lansdale PA, US
Alan X. Huang - San Mateo CA, US
Haolun Jin - Foster City CA, US
Choung U. Kim - San Carlos CA, US
Thorsten A. Kirschberg - Belmont CA, US
Steven Krawczyk - Palo Alto CA, US
Christopher P. Lee - San Francisco CA, US
William A. Lee - Los Altos CA, US
Kuei-Ying Lin - Fremont CA, US
Richard L. Mackman - Millbrae CA, US
David Y. Markevitch - Los Angeles CA, US
Peter H. Nelson - Los Altos CA, US
David A. Oare - Belmont CA, US
Vidya K. Prasad - Munich, DE
Hyung-Jung Pyun - Fremont CA, US
Adrian S. Ray - San Mateo CA, US
Rosemarie Sherlock - San Mateo CA, US
Sundaramoorthi Swaminathan - Burlingame CA, US
William J. Watkins - Sunnyvale CA, US
Jennifer R. Zhang - Foster City CA, US
Lijun Zhang - Palo Alto CA, US

Assignee:

Gilead Sciences, Inc. - Foster City CA

International Classification:

A61K 31/661
A61K 31/662
C07F 9/06
C07F 9/28

US Classification:

514112, 558168

Abstract:

The invention is related to phosphorus substituted therapeutic agents, compositions containing such phosphorus substituted agents, and therapeutic methods that include the administration of such phosphorus substituted agents, as well as to processes and intermediates useful for preparing such agents.