Peter B Riley

US Patent:

7998505, Aug 16, 2011

Filed:

Oct 26, 2007

Appl. No.:

11/925375

Inventors:

Gregory Thoorens - Brussels, BE
Bruno Leclercq - Brussels, BE
Brian Carlin - Lawrenceville NJ, US
Peter J. Riley - Yardley PA, US
Miguel Angel Garcia - Newark DE, US

Assignee:

FMC Corporation - Philadelphia PA

International Classification:

A61K 9/20
A61K 9/50
A01N 25/00

US Classification:

424465, 424499, 514781

Abstract:

A method for the preparation of microcrystalline cellulose containing tablets by roller compaction followed by tabletting is disclosed. A tablet formulation is converted to a dry granulate by roller compaction, and the dry granulate is lubricated and compacted to a tablet. The tablet formulation comprises at least one active, an microcrystalline cellulose containing material, and, optionally other pharmaceutically acceptable excipients. The microcrystalline cellulose containing material has a maximum primary compaction tensile strength of at least 9 MPa or at least 9. 5 MPa and a secondary compaction tensile strength of at least 5 MPa, at least 5. 5 MPa, or at least 6 MPa. A method for evaluating binders is also disclosed.

US Patent:

20080033392, Feb 7, 2008

Filed:

Mar 1, 2007

Appl. No.:

11/712612

Inventors:

Olav Gaserod - Steinberg, NO
Therese Andersen - Sande I Vestfold, NO
Jan Melvik - Oslo, NO
Michael Dornish - Bekkestua, NO
Peter Riley - Yardley PA, US

International Classification:

A61M 31/00
A23L 1/00
A61K 35/12
A61P 43/00
C12N 5/00
B01D 21/01
A61K 36/02
A61K 9/00

US Classification:

604502000, 424195170, 424400000, 426534000, 435375000, 435378000, 516105000

Abstract:

The invention relates to composites comprising a polysaccharide gelled within pores of a foam, methods of preparation, and uses thereof, for example, in biomedical applications such as cell culture media and implants, controlled release delivery systems, food applications, industrial applications, and personal care applications such as cosmetic and oral hygiene. The composites of the present invention are simple to formulate using few steps and are useful for entrapping heat-sensitive components, such as cells, drugs, flavors or fragrances within the polysaccharide gel. In addition, the invention provides for a composite able to gently immobilize fragile components, such as living cells, without exposing such components to shear forces.

US Patent:

20110294904, Dec 1, 2011

Filed:

Aug 10, 2011

Appl. No.:

13/207022

Inventors:

Gregory Thoorens - Ganshoren, BE
Bruno Leclercq - Brussels, BE
Brian Carlin - Lawrenceville NJ, US
Peter J. Riley - Yardley PA, US
Miguel Angel Garcia - New Castle DE, US

Assignee:

FMC CORPORATION - Philadelphia PA

International Classification:

A61K 47/26
G01N 3/08

US Classification:

514781, 73826

Abstract:

A method for the preparation of microcrystalline cellulose containing tablets by roller compaction followed by tabletting is disclosed. A tablet formulation is converted to a dry granulate by roller compaction, and the dry granulate lubricated dry granulate and compacted to a tablet. The tablet formulation comprises at least one active, an microcrystalline cellulose containing material, and, optionally other pharmaceutically acceptable excipients. The microcrystalline cellulose containing material has a maximum primary compaction tensile strength of at least 9 MPa or at least 9.5 MPa and a secondary compaction tensile strength of at least 5 MPa, at least 5.5 MPa, or at least 6 MPa. A method for evaluating binders is also disclosed.

US Patent:

57189692, Feb 17, 1998

Filed:

Aug 25, 1993

Appl. No.:

8/111800

Inventors:

Christopher J. Sewall - Princeton NJ
Donald W. Renn - Glen Cove ME
Peter J. Riley - Camden ME
William R. Thomas - Newtown PA
Lisa E. Dumont - Rockport ME
Guy A. Crosby - Princeton NJ

Assignee:

FMC Corporation - Philadelphia PA

International Classification:

B32B 516
A23L 1216
A23L 105
A23J 100

US Classification:

4283044

Abstract:

Substantially dry, rehydratable, water-dispersible, gel-forming, porous hydrocolloid micro-particulates containing internally or internally and externally at least one water-soluble, non-gelling, hydration enhancing hydrocolloid, processes and intermediates for their preparation, and their uses.

US Patent:

56246129, Apr 29, 1997

Filed:

Jun 7, 1995

Appl. No.:

8/476989

Inventors:

Christopher J. Sewall - Princeton NJ
Donald W. Renn - Glen Cove ME
Peter J. Riley - Camden ME
William R. Thomas - Newtown PA
Lisa E. Dumont - Rockport ME
Guy A. Crosby - Princeton NJ

Assignee:

FMC Corporation - Philadelphia PA

International Classification:

B01J 1302
B01J 1304

US Classification:

264 41

Abstract:

Substantially dry, rehydratable, water-dispersible, gel-forming, porous hydrocolloid microparticulates containing internally or internally and externally at least one water-soluble, non-gelling, hydration enhancing hydrocolloid, processes and intermediates for their preparation, and their uses.