Peter C Simpson

US Patent:

6623613, Sep 23, 2003

Filed:

Oct 2, 2000

Appl. No.:

09/678351

Inventors:

Richard A. Mathies - Moraga CA
Charles A. Emrich - Berkeley CA
Peter C. Simpson - Mountain View CA

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

B01D 5702

US Classification:

204453, 204450, 204600

Abstract:

A microfabricated liquid sample loading system comprising a first plate having an array of microfabricated holes passing therethrough; a second plate positioned against the first plate, the second plate having an array of microfabricated holes passing therethrough; and a plurality of microfabricated channels disposed on a surface of at least one of the first or second plates, the microfabricated channels connecting the array of microfabricated holes in the first plate with the array of microfabricated holes in the second plate.

US Patent:

6749734, Jun 15, 2004

Filed:

Aug 28, 2000

Appl. No.:

09/649272

Inventors:

Peter C. Simpson - Oakland CA
Richard A. Mathies - Moraga CA
Adam T. Woolley - Belmont MA

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

B01D 5702

US Classification:

204547, 204450, 204600, 204453

Abstract:

A capillary array electrophoresis (CAE) micro-plate with an array of separation channels connected to an array of sample reservoirs on the plate. The sample reservoirs are organized into one or more sample injectors. One or more waste reservoirs are provided to collect wastes from reservoirs in each of the sample injectors. Additionally, a cathode reservoir is also multiplexed with one or more separation channels. To complete the electrical path, an anode reservoir which is common to some or all separation channels is also provided on the micro-plate. Moreover, the channel layout keeps the distance from the anode to each of the cathodes approximately constant.

US Patent:

6913679, Jul 5, 2005

Filed:

Feb 11, 1999

Appl. No.:

09/249274

Inventors:

Richard A. Mathies - Moraga CA, US
Brian Paegel - Berkeley CA, US
Peter C. Simpson - Oakland CA, US
Lester Hutt - Berkeley CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

G01N027/447
G01N027/453
G01N030/02
B01L003/02

US Classification:

204451, 204601, 422 70, 422 99

Abstract:

Sample component separation apparatus and methods are described. An exemplary sample component separation apparatus includes a separation channel having a turn portion configured to reduce band-broadening caused by passage of a sample through the turn portion. To reduce band broadening caused by passage of a sample through a turn portion, the turn portion may be constructed and arranged to have a sample transport characteristic that is different from the corresponding sample transport characteristic of a substantially straight portion of the separation channel. For example, the turn portion may be configured with an effective channel width that is smaller than the effective channel widths of the substantially straight portion of the separation channel. The actual channel width of the turn portion may be smaller than the channel widths of the substantially straight portion; the effective channel width of the turn portion may be reduced by placing one or more sample transport barriers or constrictions in the turn portion of the channel. Alternatively, the sample velocity through the turn portion may be controlled so as to reduce band broadening.

US Patent:

7762989, Jul 27, 2010

Filed:

Feb 8, 2008

Appl. No.:

12/028409

Inventors:

Peter C. Simpson - Glencoe IL, US

Assignee:

Baxter International Inc. - Deerfield IL
Baxter Healthcare S.A. - Glattpark (Opfikon)

International Classification:

A61M 1/00
A61M 37/00

US Classification:

604151, 604131

Abstract:

A system and method for automatically delivering an infusate to a patient is disclosed. The system includes an infusion set and an infusion device. A signaling component disposed on an infusion set component identifies the infusion set and is encrypted for security. The encryption may include both an encryption algorithm and a valid number algorithm. A detection device operatively connected to the infusion device decrypts and detects the signaling component and identifies the infusion set. The infusion device is then configured to operate according to an administration protocol suitable for the infusion set and an infusion device, such as an infusion pump.

US Patent:

20010035351, Nov 1, 2001

Filed:

Mar 9, 2001

Appl. No.:

09/803724

Inventors:

Peter Simpson - Palo Alto CA, US
Ezra Van Gelder - Palo Alto CA, US

International Classification:

G01N027/26

US Classification:

204/453000, 204/450000, 204/451000, 204/600000, 204/601000, 204/604000

Abstract:

The present invention provides a microfluidic analytical device and accompanying methods for injecting a sample and separating the components therein comprising an injection channel and an intersecting separation channel, the two channels formed to be in continuous fluid communication with one another. The separation channel preferably includes a separation material for resolving the components in a sample. The methods include using a first force, preferably a pressure differential, and a second force, preferably an electric field, to move samples through the microchannels. The device and methods are specially adapted to accommodate multiple sample injection and separation. Thus, the device and methods allow for increased sample throughput and are simple and inexpensive to carry out compared to related devices and methods.

US Patent:

20020040860, Apr 11, 2002

Filed:

Apr 11, 2001

Appl. No.:

09/832133

Inventors:

Dickon Isaacs - Chicago IL, US
Peter Simpson - Lafayette CO, US
Jerimiah O'Leary - Chicago IL, US
Jonathan Kaplan - Palo Alto CA, US
Mark Zeh - Mountain View CA, US
Steven Atkins - Redwood City CA, US
Hans-Christoph Haenlein - Cupertino CA, US
Mark Stein - Arlington VA, US
Timothy Ogilvie - New York NY, US

International Classification:

B65D085/00
G08B013/14

US Classification:

206/459100, 340/569000, 340/574000

Abstract:

A method for assembling an unattended delivery device is provided. The method includes the steps of fastening a base to a first external surface, in which the base has a first base weight, and fastening a floor to the base. The method further includes the steps of fastening three walls to the floor, fastening a top to the walls, fastening an electronic assembly base to the top, and fastening an electronic assembly to the electronic assembly base. The method also includes the steps of fastening an electronic assembly cover to the walls and attaching a door to one end of one of the walls, in which the door, the walls, the top, and the floor form an enclosure. An apparatus for unattended delivery is provided. The apparatus includes a base fastened to a first external surface, in which the base has a first base weight, a floor fastened to the base, and three walls fastened to the floor. The apparatus further includes a top fastened to the walls, an electronic assembly base fastened to the top, and an electronic assembly fastened to the electronic assembly base. The apparatus also includes an electronic assembly cover fastened to the walls and a door attached to one end of one of the walls, in which the door, the walls, the top, and the floor form an enclosure.

US Patent:

20020068357, Jun 6, 2002

Filed:

Aug 9, 2001

Appl. No.:

09/927431

Inventors:

Richard Mathies - Moraga CA, US
Eric Lagally - Berkeley CA, US
Peter Simpson - San Francisco CA, US

International Classification:

C12M001/38

US Classification:

435/287200, 435/303100, 435/288500

Abstract:

A miniature device has a body including one, two or more reaction chambers. The reaction chambers are constructed for one or more of the following: sample acquisition, preparation or analysis. Preferably, a sample preparation reaction includes nucleic acid extraction, amplification, nucleic acid fragmentation, labeling, extension or a transcription.

US Patent:

20050019902, Jan 27, 2005

Filed:

Aug 14, 2004

Appl. No.:

10/918575

Inventors:

Richard Mathies - Moraga CA, US
Eric Lagally - Berkeley CA, US
Peter Simpson - San Francisco CA, US

International Classification:

C12M001/38

US Classification:

435287200, 435286100, 435303100

Abstract:

A miniature device has a body including one, two or more reaction chambers. The reaction chambers are constructed for one or more of the following: sample acquisition, preparation or analysis. Preferably, a sample preparation reaction includes nucleic acid extraction, amplification, nucleic acid fragmentation, labeling, extension or a transcription.