Peter C Young

US Patent:

6342371, Jan 29, 2002

Filed:

Apr 16, 1999

Appl. No.:

09/293625

Inventors:

Peter C McDonnell - Elkins Park PA
Peter R Young - St Davids PA

Assignee:

SmithKline Beecham Corporation - Philadephia PA

International Classification:

C12P 2106

US Classification:

435 691, 4353201, 435325, 435335, 435455, 536 231, 536 235, 530350, 530351

Abstract:

The IL-1H4 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing IL-1H4 polypeptides and polynucleotides in therapy, and diagnostic assays for such.

US Patent:

6346388, Feb 12, 2002

Filed:

May 6, 1998

Appl. No.:

09/072993

Inventors:

Michael R. Brigham-Burke - King of Prussia PA
Peter R. Young - Lawrenceville NJ

Assignee:

SmithKline Beecham Corporation - Philadelphia PA

International Classification:

G01N 3353

US Classification:

435 71, 435 4, 435 72, 435 78, 530350, 530810, 530812

Abstract:

The present invention relates to tumor necrosis factor receptor (TNF-R) related polypeptides and their ligands, hereinafter referred to as TR1, TR2, TL2 and TL4. The invention relates to methods to identify agonists and antagonists of TR1, TR2, TL2 and TL4.

US Patent:

7801747, Sep 21, 2010

Filed:

May 22, 2006

Appl. No.:

11/438677

Inventors:

Andrea Califano - New York NY, US
Aristidis Floratos - Astoria NY, US
David Wang - Killdeere IL, US
Peter Young - New York NY, US
Arthur Holden - Winnetka IL, US

Assignee:

Cerner Innovation, Inc. - Overland Park KS

International Classification:

G06F 19/00

US Classification:

705 3, 705 2, 600300, 434350, 713165

Abstract:

The systems and methods provide a dynamic process for obtaining and managing informed consent documentation. In general, the dynamic informed consent process (DICP) makes use of an intermediary organization, e. g. , a trusted intermediary, which: (a) provides ICFs which have been dynamically generated for a specified trial or medical procedure and based on particular state or federal requirements, if any; and (b) archives copies of signed ICFs. In certain preferred embodiments, there may also be a procedure to provide training materials, such as audio or video presentations, to be viewed by prospective participants. In certain preferred embodiments, the process also includes contacting subjects who have signed ICFs in the event that there is a change of circumstance which the subject may deem material to whether s/he would continue to consent, or whether the participant needs to provide a different type of consent to participate in particular event or trial.

US Patent:

20020052473, May 2, 2002

Filed:

Feb 20, 2001

Appl. No.:

09/788963

Inventors:

Sanjay Kumar - Audubon PA, US
Peter McDonnell - Thousand Oaks CA, US
Peter Young - Wilmington DE, US

International Classification:

C07K001/00
C07K014/00
C07K017/00
C07H021/02
C07H021/04

US Classification:

530/350000, 536/023100

Abstract:

The IL-1H4 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing IL-1H4 polypeptides and polynucleotides in therapy, and diagnostic assays for such.

US Patent:

20020115110, Aug 22, 2002

Filed:

Oct 25, 2001

Appl. No.:

10/066209

Inventors:

Michael Brigham-Burke - King of Prussia PA, US
Peter Young - Lawrenceville NJ, US

International Classification:

G01N033/53
A61K031/00

US Classification:

435/007100, 514/001000

Abstract:

The present invention relates to tumor necrosis factor receptor (TNF-R) related polypeptides and their ligands, hereinafter referred to as TR1, TR2, TL2 and TL4. The invention relates to methods to identify agonists and antagonists of TR1, TR2, TL2 and TL4.

US Patent:

20030033168, Feb 13, 2003

Filed:

Apr 15, 2002

Appl. No.:

10/122711

Inventors:

Andrea Califano - New York NY, US
Aristidis Floratos - Astoria NY, US
David Wang - Killdeere IL, US
Peter Young - New York NY, US
Arthur Holden - Winnetka IL, US

International Classification:

G06F017/60

US Classification:

705/003000

Abstract:

The systems and methods provide a dynamic process for obtaining and managing informed consent documentation. In general, the dynamic informed consent process (DICP) makes use of an intermediary organization, e.g., a trusted intermediary, which: (a) provides ICFs which have been dynamically generated for a specified trial or medical procedure and based on particular state or federal requirements, if any; and (b) archives copies of signed ICFs. In certain preferred embodiments, there may also be a procedure to provide training materials, such as audio or video presentations, to be viewed by prospective participants. In certain preferred embodiments, the process also includes contacting subjects who have signed ICFs in the event that there is a change of circumstance which the subject may deem material to whether s/he would continue to consent, or whether the participant needs to provide a different type of consent to participate in particular event or trial.

US Patent:

20030039362, Feb 27, 2003

Filed:

Aug 24, 2001

Appl. No.:

09/939200

Inventors:

Andrea Califano - New York NY, US
Aris Floratos - Astoria NY, US
David Wang - Killdeere IL, US
Peter Young - New York NY, US

International Classification:

H04L009/00

US Classification:

380/283000, 705/051000

Abstract:

Methods for indexing and storing genetic data include assigning a virtual private identity (VPI) to participants in a clinical study. The VPI may comprise a random number, or some other type of identifier that lacks any information that may be employed, in and of itself, to determine identity information. The system may then create an encrypted and secure database that contains the pairing between patient identity information and the assigned VPI. Information collected from the patient may be stored into data tables of a database where the VPI is employed as an index into the tables that store the patient data. The data stored in association with a respective VPI may be encrypted with an encryption key generated from the VPI. The encryption key may be stored in a Key Table and the Key Table may be encrypted with a Master Key.

US Patent:

20030064481, Apr 3, 2003

Filed:

Jan 16, 2002

Appl. No.:

10/050227

Inventors:

Michael Browne - Welwyn Garden City, GB
Peter Young - Lawrenceville NJ, US
Allan Shatzman - King of Prussia PA, US
Kay Murphy - Hertford, GB
Conrad Chapman - Orpington, GB
Helen Clinkenbeard - Hertford, GB

Assignee:

SmithKline Beecham Corporation and SmithKline Beecham p.l.c.

International Classification:

C12P021/04
C07K016/46
C12P021/02
C12N005/06

US Classification:

435/069520, 424/085200, 530/351000, 435/325000, 435/320100

Abstract:

A soluble protein having IL4 and/or IL13 antagonist or partial antagonist activity comprises an IL4 mutant or variant fused to least one human immunoglobulin constant domain or fragment thereof.