A protective brassiere that protects the delicate breast tissue and the related glandular areas from harmful radiation. The protective brassiere includes a generally concave-shaped right cup, a generally concave-shaped left cup that is disposed adjacent to the generally concave-shaped right cup, a generally elongated right side panel that is disposed adjacent to the generally concave-shaped right cup, a generally elongated left side panel that is disposed adjacent to the generally concave-shaped left cup, a removably mounted generally convex-shaped right cup protective insert of electrically conductive material that is removably mounted to the generally concave-shaped right cup, a removably mounted generally convex-shaped left cup protective insert of electrically conductive material that is removably mounted to the generally concave-shaped left cup, a removably mounted generally elongated right side panel protective insert of electrically conductive material that is removably mounted to the generally elongated right side panel, and a removably mounted generally elongated left side panel protective insert of electrically conductive material that is removably mounted to the generally elongated left side panel.