Tesfaye Biftu - Freehold NJ, US Ping Chen - Edison NJ, US Danqing Feng - Green Brook NJ, US Ann E. Weber - Scotch Plains NJ, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
A61K 31/50
US Classification:
51425505, 544350, 549424
Abstract:
The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Aminotetrahydropyrans As Dipeptidyl Peptidase-Iv Inhibitors For The Treatment Or Prevention Of Diabetes
Tesfaye Biftu - Freehold NJ, US Charles G Caldwell - Dallas TX, US Ann E. Weber - Scotch Plains NJ, US Ping P Chen - Edison NJ, US Xiaoxia Qian - New York NY, US Danqing Feng - Branchburg NJ, US Jason M. Cox - East Windsor NJ, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
A01N 43/90 A61K 31/519 C07D 487/00
US Classification:
5142651, 544280
Abstract:
The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Substituted 5,6,7,8-Tetrahydropyrido[4,3-D]Pyrimidines As Dipeptidyl Peptidase-Iv Inhibitors For The Treatment Or Prevention Of Diabetes
Tesfaye Biftu - Freehold NJ, US Ping Chen - Edison NJ, US Danqing Feng - Green Brook NJ, US Ann E. Weber - Scotch Plains NJ, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
A61K 31/519
US Classification:
5142641, 544279, 549424
Abstract:
The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Aminotetrahydropyrans As Dipeptidyl Peptidase-Iv Inhibitors For The Treatment Or Prevention Of Diabetes
The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Aminotetrahydropyrans As Dipeptidyl Peptidase-Iv Inhibitors For The Treatment Or Prevention Of Diabetes
Tesfaye Biftu - Freehold NJ, US Ping Chen - Edison NJ, US Danqing Feng - Green Brook NJ, US Xiaoxia Qian - New York NY, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
A61K 31/4162 C07D 231/00
US Classification:
514406, 5483605
Abstract:
The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Compounds Useful For Treating Disorders Related To Trpa1
Xinyuan Wu - Newton MA, US Spencer David Kimball - East Windsor NJ, US Ping Chen - Franklin Park NJ, US Ding Zhou - Shanghai, CN Shaoping Peng - Shanghai, CN
Assignee:
Hydra Biosciences, Inc. - Cambridge MA
International Classification:
A01N 43/54 A61K 31/505 C07D 239/00 C07D 471/00
US Classification:
514267, 544250
Abstract:
Compounds and compositions for treating disorders related to TRPA1 are described herein.
Aminotetrahydropyrans As Dipeptidyl Peptidase-Iv Inhibitors For The Treatment Or Prevention Of Diabetes
Tesfaye Biftu - Freehold NJ, US Ping Chen - Edison NJ, US Jason M. Cox - East Windsor NJ, US Ann E. Weber - Scotch Plains NJ, US
International Classification:
A61K 31/4162 A61K 38/28 A61P 3/10 C07D 487/04
US Classification:
514 65, 5483605, 514407
Abstract:
The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Novel Cyclic Azabenzimidazole Derivatives Useful As Anti-Diabetic Agents
Rajan Anand - Fanwood NJ, US James M. Apgar - Highland Park NJ, US Tesfaye Biftu - Freehold NJ, US Ping Chen - Edison NJ, US Lin Chu - Scotch Plains NJ, US Vincent J. Colandrea - North Brunswick NJ, US Guizhen Dong - Dayton NJ, US James F. Dropinski - Colts Neck NJ, US Danqing Feng - Green Brook NJ, US Jacqueline D. Hicks - Scotch Plains NJ, US Jinlong Jiang - Scotch Plains NJ, US Alexander J. Kim - Morganville NJ, US Kenneth J. Leavitt - Plainsboro NJ, US Bing Li - Towaco NJ, US Xiaoxia Qian - New York NY, US Iyassu Sebhat - Jersey City NJ, US Lan Wei - Berkeley Heights NJ, US Robert R. Wilkening - Maplewood NJ, US Zhicai Wu - Montvale NJ, US
Novel compounds of structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension.
Sep 2009 to 2000 Sr. Process Development EngineerSOLASTA Newton, MA Oct 2009 to Mar 2010 Sr. Process EngineerANALOG DEVICES Cambridge, MA May 2007 to Oct 2009 Sr. Process EngineerSKYWORKS SOLUTIONS Woburn, MA May 2006 to May 2007 Process EngineerUNIVERSITY OF ALABAMA Tuscaloosa, AL Aug 2001 to Sep 2005 Research Assistant
Education:
University of Alabama Tuscaloosa, AL Aug 2005 Ph.D. in Chemical EngineeringResearch Institute of Petroleum Processing 2000 M.S. in Chemical EngineeringJiangsu Institute of Petrochemical Technology 1995 B.E. in Chemical Engineering
Mar 2011 to Present Product controller, Middle OfficeCITCO Fund Services Ltd
Sep 2007 to Mar 2011 Manager, P&L Analytical / ValuationBank of New York Mellon, NJ New York, NY Nov 2005 to Aug 2007 Analyst II, Global Asset Management
Education:
Temple University, Fox Business School Philadelphia, PA May 2005 Master in FinancePhiladelphia University Philadelphia, PA May 2003 Bachelor in Computer & Information Science
Southeastern Integrated MedicalSoutheast Integrated Medical Rehabilitation Medicine 1315 NW 21 Ave STE 2, Chiefland, FL 32626 3524931655 (phone), 3524908641 (fax)
Languages:
English
Description:
Ms. Chen works in Chiefland, FL and specializes in Physical Medicine & Rehabilitation. Ms. Chen is affiliated with UF Health Shands Rehabilitation Hospital.
Youtube
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Ping Chen Interview
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(Full Audiobook) Land of Big Numbers by Te Pi...
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6h 37m 22s
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(2/09/21) Gripping and compassionate, Land of Big Numbers traces the j...
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Googleplus
Ping Chen
Work:
Google, Inc - Software Engineer (2006) America Online
Education:
University of California, Irvine
Relationship:
Married
About:
I love building cool stuff, but I love taking photos even more :) Other hobbies include food and travel Disclaimer: The views expressed by me are mine (all mine!) and not my employer's.
Bragging Rights:
Climbed down 71 flights of stairs in Taipei 101 building