Poothappillai K Kasinathan

age ~67

from Brier, WA

Also known as:
  • Poothappil Etal Kasinathan
  • Poothappil K Kasinathan
  • Poothappil P Kasinathan
  • Poothapill Kasinathan
  • Kasinathan Poothappillai
  • Kasinathan Poothappil

Poothappillai Kasinathan Phones & Addresses

  • Brier, WA
  • Brandon, SD
  • 1901 Dorothy Ave, Sioux Falls, SD 57106 • 6053626057
  • 1540 Waterford Pl, Manhattan, KS 66502 • 7857709071
  • Amherst, MA
  • 26608 Caley Cir, Brandon, SD 57005

Us Patents

  • Transgenic Bovines Capable Of Human Antibody Production

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  • US Patent:
    7414170, Aug 19, 2008
  • Filed:
    May 19, 2003
  • Appl. No.:
    10/441503
  • Inventors:
    James M. Robl - Brandon SD, US
    Poothappillai Kasinathan - Sioux Falls SD, US
    Richard A. Goldsby - Leverett MA, US
    Yoshimi Kuroiwa - Sioux Falls SD, US
    Kazuma Tomizuka - Takasaki, JP
    Isao Ishida - Isehara, JP
    Barbara Osborne - Leverett MA, US
  • Assignee:
    Kirin Beer Kabushiki Kaisha - Tokyo
  • International Classification:
    A01K 67/027
    C12P 21/00
    C12N 15/00
  • US Classification:
    800 15, 800 5, 800 6, 800 25
  • Abstract:
    The invention features novel methods for the production of large quantities of xenogenous antibodies, such as human antibodies. Preferably, this result is effected by inactivation of IgM heavy chain expression and, optionally, by inactivation of Ig light chain expression, and by the further introduction of an artificial chromosome which results in the expression of xenogenous antibodies (e. g. , non-bovine antibodies), preferably human antibodies.
  • Transgenic Animals And Uses Thereof

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  • US Patent:
    7420099, Sep 2, 2008
  • Filed:
    Apr 21, 2005
  • Appl. No.:
    11/111310
  • Inventors:
    James M. Robl - Brandon SD, US
    Yoshimi Kuroiwa - Sioux Falls SD, US
    Poothappillai Kasinathan - Sioux Falls SD, US
    Isao Ishida - Isehara, JP
    Kazuma Tomizuka - Takasaki, JP
  • Assignee:
    Kirin Holdings Kabushiki Kaisha - Tokyo
  • International Classification:
    A01K 67/027
    C12P 21/00
    C12N 15/00
  • US Classification:
    800 15, 800 6, 800 25
  • Abstract:
    In general, the invention features genetically modified non-human mammals (e. g. , bovines and other ungulates), and methods of making these mammals. In particular, the invention features transgenic ungulates having reduced levels of endogenous IgM heavy chain and/or prion protein.
  • Transgenic Ungulates Capable Of Human Antibody Production

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  • US Patent:
    7803981, Sep 28, 2010
  • Filed:
    Jun 20, 2007
  • Appl. No.:
    11/820768
  • Inventors:
    James M. Robl - Brandon SD, US
    Philippe Collas - Oslo, NO
    Eddie Sullivan - Tea SD, US
    Poothappillai Kasinathan - Sioux Falls SD, US
    Richard A. Goldsby - Leverett MA, US
    Yoshimi Kuroiwa - Sioux Falls SD, US
    Kazuma Tomizuka - Takasaki, JP
    Isao Ishida - Isehara, JP
    Barbara Osborne - Leverett MA, US
  • Assignee:
    Kyowa Hakko Kirin Co., Ltd. - Tokyo
  • International Classification:
    C12P 33/00
    A01K 67/027
    C12N 5/00
  • US Classification:
    800 15, 800 4, 800 5, 800 16, 800 17, 435325
  • Abstract:
    The invention features novel methods for the production of large quantities of xenogenous antibodies, such as human antibodies. Preferably, this result is effected by inactivation of IgM heavy chain expression and, optionally, by inactivation of Ig light chain expression, and by the further introduction of an artificial chromosome which results in the expression of xenogenous antibodies (e. g. , non-bovine antibodies), preferably human antibodies.
  • Method Of Producing Xenogenous Antibodies Using A Bovine

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  • US Patent:
    7928285, Apr 19, 2011
  • Filed:
    Jun 25, 2008
  • Appl. No.:
    12/215085
  • Inventors:
    James M. Robl - Brandon SD, US
    Yoshimi Kuroiwa - Sioux Falls SD, US
    Poothappillai Kasinathan - Sioux Falls SD, US
    Isao Ishida - Isehara, JP
    Kazuma Tomizuka - Takasaki, JP
  • Assignee:
    Kyowa Hakko Kirin Co., Ltd. - Tokyo
  • International Classification:
    A01K 67/00
    A01K 67/027
    A01K 67/033
    C12P 21/00
    C12N 15/00
  • US Classification:
    800 4, 800 15, 800 5, 800 6, 800 7, 800 8, 800 14, 800 21
  • Abstract:
    In general, the invention features genetically modified non-human mammals (e. g. , bovines and other ungulates), and methods of making these mammals. In particular, the invention features transgenic ungulates having reduced levels of endogenous IgM heavy chain and/or prion protein.
  • Transgenic Animals And Uses Thereof

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  • US Patent:
    20110231943, Sep 22, 2011
  • Filed:
    Apr 6, 2011
  • Appl. No.:
    13/080923
  • Inventors:
    JAMES M. ROBL - BRANDON SD, US
    YOSHIMI KUROIWA - SIOUX FALLS SD, US
    POOTHAPPILLAI KASINATHAN - SIOUX FALLS SD, US
    ISAO ISHIDA - ISEHARA, JP
    KAZUMA TOMIZUKA - TAKASAKI, JP
  • Assignee:
    KYOWA HAKKO KIRIN CO., LTD. - TOKYO
  • International Classification:
    A01K 67/027
  • US Classification:
    800 15, 800 14, 800 17, 800 16
  • Abstract:
    In general, the invention features genetically modified non-human mammals (e.g., bovines and other ungulates), and methods of making these mammals. In particular, the invention features transgenic ungulates having reduced levels of endogenous IgM heavy chain and/or prion protein.
  • Methods For Cloning Non-Human Mammals Using Reprogrammed Donor Chromatin Or Donor Cells

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  • US Patent:
    7253334, Aug 7, 2007
  • Filed:
    Dec 21, 2001
  • Appl. No.:
    10/032191
  • Inventors:
    Philippe Collas - Oslo, NO
    James M. Robl - Belchertown MA, US
    Eddie Sullivan - Manhattan KS, US
    Poothappillai Kasinathan - Brandon SD, US
  • Assignee:
    Aurox, LLC - Westport CT
  • International Classification:
    C12N 15/00
    G01N 33/00
    C12P 21/00
    A01K 67/00
  • US Classification:
    800 24, 800 3, 800 4, 800 8, 800 21, 800 25, 435325
  • Abstract:
    The invention provides methods for cloning mammals that allow the donor chromosomes or donor cells to be reprogrammed prior to insertion into an enucleated oocyte. The invention also features methods of inserting chromosomes or nuclei into recipient cells.

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