Qi X Chen

US Patent:

20130115193, May 9, 2013

Filed:

Nov 8, 2012

Appl. No.:

13/672266

Inventors:

Bristol-Myers Squibb Company - Princeton NJ, US
John A. Bender - Middletown CT, US
Zhong Yang - Southington CT, US
Makonen Belema - North Haven CT, US
Omar D. Lopez - Wallingford CT, US
Qi Chen - Elmhurst NY, US
Gan Wang - Cheshire CT, US
Piyasena Hewawasam - Middletown CT, US

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

C07D 403/14
A61K 31/4545
C07D 401/14
A61K 31/437
C07D 471/04
A61K 31/4985
C07D 487/04
C07D 405/14
A61K 31/498
A61K 31/4178
A61K 31/4375
A61K 31/4709
A61K 31/5377
C07D 413/14
C07D 403/10
A61K 45/06
A61K 31/4184

US Classification:

424 852, 424 857, 514394, 5483054, 514316, 546187, 514303, 546118, 514249, 544350, 5483131, 544353, 514397, 546122, 514300, 546167, 514314, 5142322, 544 82, 5483137, 514 43, 514 44 A

Abstract:

The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.

US Patent:

20130121957, May 16, 2013

Filed:

May 7, 2012

Appl. No.:

13/465298

Inventors:

Qi Chen - Stamford CT, US
Omar D. Lopez - Wallingford CT, US
John A. Bender - Middletown CT, US
Gan Wang - Cheshire CT, US
Van N. Nguyen - Meriden CT, US
John F. Kadow - Wallingford CT, US
Nicholas A. Meanwell - East Hampton CT, US
Makonen Belema - North Haven CT, US

International Classification:

C07D 403/14
A61K 45/06
A61K 31/4184
A61K 31/5377
A61K 31/4178
C07D 405/14

US Classification:

424 852, 514397, 5483007, 5483121, 514394, 5142322, 544 70, 424 854, 514 43, 514 44 A, 5483131, 424 857, 514293

Abstract:

The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.

US Patent:

20140018389, Jan 16, 2014

Filed:

Sep 16, 2013

Appl. No.:

14/027531

Inventors:

John A. Bender - Middletown CT, US
Jeffrey Lee Romine - Meriden CT, US
Edward H. Ruediger - Greenfield Park, CA
Carol Bachand - Candiac, CA
Omar D. Lopez - Wallingford CT, US
Qi Chen - Elmhurst NY, US
Makonen Belema - North Haven CT, US
John F. Kadow - Wallingford CT, US
Lawrence G. Hamann - North Grafton MA, US

International Classification:

C07D 417/14
C07D 405/14
C07D 401/14
C07D 403/14
C07D 409/14
C07D 413/14

US Classification:

514316, 5483131, 514397, 548204, 514365, 548236, 514374, 546187, 5483121

Abstract:

This disclosure concerns novel compounds of Formula (I) or as defined in the specification and compositions comprising such novel compounds. These compounds are useful antiviral agents, especially in inhibiting the function of the NS5A protein encoded by Hepatitis C virus (HCV). Thus, the disclosure also concerns a method of treating HCV related diseases or conditions by use of these novel compounds or a composition comprising such novel compounds.

US Patent:

20150322048, Nov 12, 2015

Filed:

Jul 23, 2015

Appl. No.:

14/807084

Inventors:

- Princeton NJ, US
John A. Bender - Middletown CT, US
Zhong Yang - Southington CT, US
Makonen Belema - North Haven CT, US
Omar D. Lopez - Wallingford CT, US
Qi Chen - Elmhurst NY, US
Gan Wang - Cheshire CT, US
Piyasena Hewawasam - Middletown CT, US

International Classification:

C07D 403/14
A61K 45/06
A61K 31/4178
A61K 31/4545
C07D 471/04
A61K 31/437
C07D 487/04
A61K 31/4985
C07D 405/14
C07D 401/14
A61K 31/4709
A61K 31/498
A61K 31/4375
C07D 413/14
A61K 31/5377
A61K 31/4184

Abstract:

The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.

US Patent:

20150197499, Jul 16, 2015

Filed:

Mar 25, 2015

Appl. No.:

14/668090

Inventors:

- Princeton NJ, US
John A. Bender - Middletown CT, US
Zhong Yang - Southington CT, US
Makonen Belema - North Haven CT, US
Omar D. Lopez - Wallingford CT, US
Qi Chen - Elmhurst NY, US
Gan Wang - Cheshire CT, US
Piyasena Hewawasam - Middletown CT, US

International Classification:

C07D 309/06

Abstract:

The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.