Qi Fen Chen

US Patent:

20130115193, May 9, 2013

Filed:

Nov 8, 2012

Appl. No.:

13/672266

Inventors:

Bristol-Myers Squibb Company - Princeton NJ, US
John A. Bender - Middletown CT, US
Zhong Yang - Southington CT, US
Makonen Belema - North Haven CT, US
Omar D. Lopez - Wallingford CT, US
Qi Chen - Elmhurst NY, US
Gan Wang - Cheshire CT, US
Piyasena Hewawasam - Middletown CT, US

Assignee:

Bristol-Myers Squibb Company - Princeton NJ

International Classification:

C07D 403/14
A61K 31/4545
C07D 401/14
A61K 31/437
C07D 471/04
A61K 31/4985
C07D 487/04
C07D 405/14
A61K 31/498
A61K 31/4178
A61K 31/4375
A61K 31/4709
A61K 31/5377
C07D 413/14
C07D 403/10
A61K 45/06
A61K 31/4184

US Classification:

424 852, 424 857, 514394, 5483054, 514316, 546187, 514303, 546118, 514249, 544350, 5483131, 544353, 514397, 546122, 514300, 546167, 514314, 5142322, 544 82, 5483137, 514 43, 514 44 A

Abstract:

The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.

US Patent:

20130121957, May 16, 2013

Filed:

May 7, 2012

Appl. No.:

13/465298

Inventors:

Qi Chen - Stamford CT, US
Omar D. Lopez - Wallingford CT, US
John A. Bender - Middletown CT, US
Gan Wang - Cheshire CT, US
Van N. Nguyen - Meriden CT, US
John F. Kadow - Wallingford CT, US
Nicholas A. Meanwell - East Hampton CT, US
Makonen Belema - North Haven CT, US

International Classification:

C07D 403/14
A61K 45/06
A61K 31/4184
A61K 31/5377
A61K 31/4178
C07D 405/14

US Classification:

424 852, 514397, 5483007, 5483121, 514394, 5142322, 544 70, 424 854, 514 43, 514 44 A, 5483131, 424 857, 514293

Abstract:

The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.

US Patent:

20140018389, Jan 16, 2014

Filed:

Sep 16, 2013

Appl. No.:

14/027531

Inventors:

John A. Bender - Middletown CT, US
Jeffrey Lee Romine - Meriden CT, US
Edward H. Ruediger - Greenfield Park, CA
Carol Bachand - Candiac, CA
Omar D. Lopez - Wallingford CT, US
Qi Chen - Elmhurst NY, US
Makonen Belema - North Haven CT, US
John F. Kadow - Wallingford CT, US
Lawrence G. Hamann - North Grafton MA, US

International Classification:

C07D 417/14
C07D 405/14
C07D 401/14
C07D 403/14
C07D 409/14
C07D 413/14

US Classification:

514316, 5483131, 514397, 548204, 514365, 548236, 514374, 546187, 5483121

Abstract:

This disclosure concerns novel compounds of Formula (I) or as defined in the specification and compositions comprising such novel compounds. These compounds are useful antiviral agents, especially in inhibiting the function of the NS5A protein encoded by Hepatitis C virus (HCV). Thus, the disclosure also concerns a method of treating HCV related diseases or conditions by use of these novel compounds or a composition comprising such novel compounds.

US Patent:

20220383640, Dec 1, 2022

Filed:

Mar 31, 2022

Appl. No.:

17/710833

Inventors:

- Boston MA, US
Qi Chen - Baltimore MD, US

International Classification:

G06V 20/58
G06T 7/10
G06V 10/40
G06V 10/82

Abstract:

Among other things, techniques for detecting objects in the environment surrounding a vehicle are described. A computer system is configured to receive a set of measurements from a sensor of a vehicle. The set of measurements includes a plurality of data points that represent a plurality of objects in a 3D space surrounding the vehicle. The system divides the 3D space into a plurality of pillars. The system then assigns each data point of the plurality of data points to a pillar in the plurality of pillars. The system generates a pseudo-image based on the plurality of pillars. The pseudo-image includes, for each pillar of the plurality of pillars, a corresponding feature representation of data points assigned to the pillar. The system detects the plurality of objects based on an analysis of the pseudo-image. The system then operates the vehicle based upon the detecting of the objects.

US Patent:

20220371606, Nov 24, 2022

Filed:

Mar 31, 2022

Appl. No.:

17/710895

Inventors:

- Boston MA, US
Qi Chen - Baltimore MD, US

International Classification:

B60W 50/00
G01C 21/00
B60W 60/00

Abstract:

Among other things, techniques for detecting objects in the environment surrounding a vehicle are described. A computer system is configured to receive a set of measurements from a sensor of a vehicle. The set of measurements includes a plurality of data points that represent a plurality of objects in a 3D space surrounding the vehicle. The system divides the 3D space into a plurality of pillars. The system then assigns each data point of the plurality of data points to a pillar in the plurality of pillars. The system generates a pseudo-image based on the plurality of pillars. The pseudo-image includes, for each pillar of the plurality of pillars, a corresponding feature representation of data points assigned to the pillar. The system detects the plurality of objects based on an analysis of the pseudo-image. The system then operates the vehicle based upon the detecting of the objects.

US Patent:

20210157006, May 27, 2021

Filed:

Aug 4, 2020

Appl. No.:

16/985092

Inventors:

- Suwon-si, KR
Qi Chen - Baltimore MD, US

International Classification:

G01S 17/894
G06T 15/00
G06T 11/00
G06N 3/02
G05D 1/00

Abstract:

A system and method for three-dimensional (3D) object classification are disclosed. A computing system receives point cloud data from an input source. The point cloud data may include first and second points in 3D space. The first point may represent a feature of an object. The computing system invokes a neural network for classifying the first point with a first label, and regresses a bounding box based on classifying the first point with the first label. Regressing the bounding box includes predicting at least a location of the bounding box. The computing system may control an autonomous vehicle based on regressing the bounding box.

US Patent:

20150322048, Nov 12, 2015

Filed:

Jul 23, 2015

Appl. No.:

14/807084

Inventors:

- Princeton NJ, US
John A. Bender - Middletown CT, US
Zhong Yang - Southington CT, US
Makonen Belema - North Haven CT, US
Omar D. Lopez - Wallingford CT, US
Qi Chen - Elmhurst NY, US
Gan Wang - Cheshire CT, US
Piyasena Hewawasam - Middletown CT, US

International Classification:

C07D 403/14
A61K 45/06
A61K 31/4178
A61K 31/4545
C07D 471/04
A61K 31/437
C07D 487/04
A61K 31/4985
C07D 405/14
C07D 401/14
A61K 31/4709
A61K 31/498
A61K 31/4375
C07D 413/14
A61K 31/5377
A61K 31/4184

Abstract:

The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.

US Patent:

20150197499, Jul 16, 2015

Filed:

Mar 25, 2015

Appl. No.:

14/668090

Inventors:

- Princeton NJ, US
John A. Bender - Middletown CT, US
Zhong Yang - Southington CT, US
Makonen Belema - North Haven CT, US
Omar D. Lopez - Wallingford CT, US
Qi Chen - Elmhurst NY, US
Gan Wang - Cheshire CT, US
Piyasena Hewawasam - Middletown CT, US

International Classification:

C07D 309/06

Abstract:

The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.