Qian Li

US Patent:

7790896, Sep 7, 2010

Filed:

Mar 1, 2007

Appl. No.:

11/680731

Inventors:

Young-Tae Chang - New York NY, US
Qian Li - New York NY, US
Gustavo Rosania - Ann Arbor MI, US

Assignee:

New York University - New York NY

International Classification:

C07D 215/38

US Classification:

546178

Abstract:

The present invention is directed to fluorescent compounds and methods of making said compounds that selectively bind to cellular RNA. The fluorescent compounds of the present invention are useful for live cell imaging applications.

US Patent:

8158380, Apr 17, 2012

Filed:

Feb 11, 2008

Appl. No.:

12/029271

Inventors:

Thomas Wisniewski - Staten Island NY, US
Jaeki Min - Marietta GA, US
Qian Li - Frederick MD, US
Young-Tae Chang - Singapore, SG

Assignee:

New York University - New York NY

International Classification:

G01N 1/30
C07D 453/04

US Classification:

435 405, 546134

Abstract:

Charged and neutral small fluorescent molecules based upon the styryl scaffold are useful as imaging agents for misfolded proteins such as amyloid plaque. Charged molecules are prepared using pyrrolidine catalyzed reactions by solution-phase synthesis. Neutral styryl molecules are prepared using acetic anhydride catalyzed reactions, Horner-Emmons reactions or Wittig reactions.

US Patent:

20210308174, Oct 7, 2021

Filed:

Jul 22, 2019

Appl. No.:

17/266551

Inventors:

- Baltimore MD, US
Lian Sheng Liu - Ellicott City MD, US
Qian Li - Ellicott City MD, US
Alfred Spormann - Stanford CA, US

International Classification:

A61K 33/00
A61K 9/00
A61P 1/00

Abstract:

Described are methods for treating or preventing IBS in subjects by administering molybdenum or a salt thereof to subjects having or prone of getting IBS. The molybdenum has been shown to treat or prevent IBS in subjects administered this agent when compared to reference subjects not administered molybdenum.