Rachel A Green

US Patent:

20080275219, Nov 6, 2008

Filed:

Jun 21, 2005

Appl. No.:

11/630595

Inventors:

Rachel Green - Baltimore MD, US
Katharina Semrad - Vienna, AT

Assignee:

The Johns Hopkins University - Baltimore MD

International Classification:

C07K 14/195
C12N 9/10
C07H 21/00
C40B 40/10
C40B 40/08
C12P 21/02

US Classification:

530358, 435193, 536 2433, 506 18, 506 17, 435 691

Abstract:

In general, the invention provides methods and compositions for the in vitro production of ribonucleoprotein complexes and related multimolecular complexes useful for cell-free methods of protein production.

US Patent:

20120022232, Jan 26, 2012

Filed:

Dec 2, 2009

Appl. No.:

13/132528

Inventors:

Rachel Green - Baltimore MD, US
Hani S. Zaher - Baltimore MD, US

Assignee:

THE JOHNS HOPKINS UNIVERSITY - Baltimore MD

International Classification:

C07K 14/00
C12P 21/00
C12N 1/19
C12N 7/01
C12N 1/00
C12N 1/21

US Classification:

530350, 435243, 43525233, 43525421, 43525423, 4352351, 435 691, 435325, 4352521, 43525411

Abstract:

The invention provides recombinant cells or recombinant restrictive cells for overexpressing one or more proteins comprising one or more release factors. The invention also provides methods for producing a recombinant protein comprising culturing the cells of the present invention under conditions such that one or more proteins are overexpressed, and then isolating the expressed recombinant protein, In certain embodiments of the present invention, the gene encoding the protein is codon optimized.

US Patent:

6358713, Mar 19, 2002

Filed:

Apr 12, 2000

Appl. No.:

09/547537

Inventors:

Rachel Green - Baltimore MD

Assignee:

Johns Hopkins University - Baltimore MD

International Classification:

C12Q 168

US Classification:

435 911, 435 6

Abstract:

Methods for selecting rRNA variants that catalyze formation of non-standard polymers are described.