Raj Kumar Chopra

US Patent:

6441050, Aug 27, 2002

Filed:

Aug 29, 2000

Appl. No.:

09/650487

Inventors:

Raj K. Chopra - Westbury NY 11590

International Classification:

A61K 3112

US Classification:

514675, 514718, 424439

Abstract:

The present invention relates to a composition in pharmaceutical dosage form of coenzyme Q or ubiquinol which can be administered to children in an oral dosage form as a pleasant-tasting liquid. The dosage form comprises an effective amount of coenzyme Q or ubiquinol ranging from about 0. 05% to about 10%, more preferably about 1% to about 7. 5% by weight of the composition in combination with a minor amount of a polysorbate surfactant such as a Tweenâ surfactant, most preferably, polysorbate 80, a major amount of a vegetable oil or triglyceride, in further combination with an amount of phospholipid such as hydroxylated lecithin effective to maintain ubiquinone/ubiquionol in hydrosoluble form and to substantially enhance the palatability of ubiquinone or ubiquinol in combination with a sweetener solution as well as an amount of water preferably ranging from about 5% to about 45% by weight.

US Patent:

6740338, May 25, 2004

Filed:

Jan 20, 2000

Appl. No.:

09/488332

Inventors:

Raj K. Chopra - Westbury NY 11590

International Classification:

A61K 964

US Classification:

424456, 424400, 424451, 424439, 424463, 424464, 424455, 514904, 514966, 514720

Abstract:

The present invention relates to a reduced form of Coenzyme Q also known as ubiquinol in oral dosage form such as a gelatin capsule, preferably a soft gelatin capsule. Compositions according to the present invention include storage stable compositions comprising effective amounts of ubiquinol in combination with an amount of a reducing agent effective to maintain ubiquinol in its reduced state when formulated in capsules, tablets and other orally administrable form. Methods of use are also disclosed.

US Patent:

20050260752, Nov 24, 2005

Filed:

Apr 1, 2003

Appl. No.:

10/403409

Inventors:

Martin Wilding - Naples, IT
Brian Dale - Sorrento, IT
Raj Chopra - Westbury NY, US

International Classification:

C12N005/00
C12N005/02

US Classification:

435373000, 435325000

Abstract:

The present invention relates to a culture medium suitable for mammalian cell, tissue or embryo growth in vitro in which enhancers of oxidative phosphorylation are included. These enhancers include coenzyme Q, alpha.lipoic acid, acetyl-L-carnitine, alpha.tocopherol, These products are introduced into the medium in a soluble form through the use of either a polysorbate surfactant such as Tween ™ or a preparation containing lecithin and surfactant.

US Patent:

20060041017, Feb 23, 2006

Filed:

Aug 10, 2005

Appl. No.:

11/201014

Inventors:

Raj Chopra - Westbury NY, US

International Classification:

A61K 31/22
A61K 31/202

US Classification:

514546000, 514560000

Abstract:

The present invention relates to the unexpected discovery that a combination of effective amounts of carnitine (in any form, as described in further detail herein) and conjugated linoleic acid (CLA) administered to a patient in need thereof exhibits synergistic activity in treating obesity by reducing fat mass and overall weight as well as one or more of hyperlipidemia, hypercholesterolemia, diabetes (both diabetes mellitus I and II), metabolic syndrome (syndrome X), kidiney failure and high blood pressure, where those conditions exist.

US Patent:

63003775, Oct 9, 2001

Filed:

Feb 22, 2001

Appl. No.:

9/790783

Inventors:

Raj K. Chopra - Westbury NY

International Classification:

A61K 31075
A61K 31355
A61K 3134
A61K 31205
A61K 3120
A61K 3107

US Classification:

514715

Abstract:

The present invention relates to a composition in liquid dosage form of coenzyme Q or ubiquinone which can be formulated into cosmetic, dietary supplement or pharmaceutical dosage form for administration to patients. The dosage form comprises an effective amount of coenzyme Q or ubiquinone ranging from about 0. 05% to about 15%, more preferably about 1% to about 10. 0% by weight of the composition in combination with a polysorbate surfactant such as a Tween. TM. , surfactant, a vegetable oil or triglyceride, in further combination with a glyceryl ester in amounts effective to produce a liquid dosage form. Optional additives include a phospholipid such as hydroxylated lecithin, among others such as tocopherols or tocopherol esters effective to solubilize the ubiquinone in combination as well as other bioactive agents. Compositions according to the present invention avoid the inclusion of a polyhydric alcohol solvent in solubilizing amounts.

US Patent:

20180161304, Jun 14, 2018

Filed:

Feb 7, 2018

Appl. No.:

15/890588

Inventors:

Stanley N. Jankowitz - Franklin Lakes NJ, US
Raj Chopra - Westbury NY, US

International Classification:

A61K 31/355
A61K 31/122
A61K 31/375
A23K 20/174
A23K 20/111
A23K 20/163
A23K 20/10
A23K 20/24
A23K 20/20
A23K 50/20
A61K 33/06
A61K 45/06
A61K 33/04

Abstract:

Disclosed herein are methods of using nutritional supplements and specific combinations thereof to counteract exercise-induced stress and its sequelae in members of the species. Particular embodiments focus on use of Coenzyme Q10, vitamin E and their variants. Methods include ascertaining and modifying the nutritional supplements, ascertaining and comparing health states of a horse, wherein the comparisons are made before and after modifications of the supplements and/or implementation of exercise regimens.

US Patent:

20150056176, Feb 26, 2015

Filed:

Nov 5, 2014

Appl. No.:

14/534074

Inventors:

STANLEY N. JANKOWITZ - Franklin Lakes NJ, US
Raj K. Chopra - Westbury NY, US

International Classification:

A61K 31/355
A61K 31/353
A61K 45/06
A61K 31/122

US Classification:

424 941, 514690

Abstract:

Disclosed herein are methods of using nutritional supplements and specific combinations thereof to counteract exercise-induced inflammation in monogastric organisms. Particular embodiments focus on use of quercetin, curcumin, CoQ10, ribose, calcium carbonate, and zinc and their variants. Methods include ascertaining and modifying the nutritional supplements, ascertaining and comparing health states of all performance athletes, wherein the comparisons are made before and after modifications of the supplements and/or implementation of exercise regimens.