Rajiv L Gupta

US Patent:

7644577, Jan 12, 2010

Filed:

Oct 31, 2005

Appl. No.:

11/262605

Inventors:

Jan-Roger Linna - Boston MA, US
Rajiv Gupta - Glen Allen VA, US
Roberto O. Pellizzari - Groton MA, US

Assignee:

Philip Morris USA, Inc. - Richmond VA

International Classification:

F01N 3/00

US Classification:

60286, 60295, 60297, 60301, 60303, 239409, 239410, 2395853, 2395854

Abstract:

A reducing agent metering system for delivering reducing agent to a lean burn internal combustion engine. The reducing agent metering system includes a metering system housing, a system for metering vaporized reducing agent to the internal combustion engine, the system positioned within the metering system housing and a system for delivering an atomized stream of liquid reducing agent to the lean burn internal combustion engine, the system positioned within the metering system housing, wherein the reducing agent metering system is operable to transition from metering vaporized reducing agent to delivering an atomized stream of liquid reducing agent to the lean burn internal combustion engine.

US Patent:

7863897, Jan 4, 2011

Filed:

Sep 8, 2008

Appl. No.:

12/206279

Inventors:

Rajiv Gupta - Wayland MA, US
Stephen E. Jones - Cleveland Heights OH, US

Assignee:

The General Hospital Corporation - Boston MA

International Classification:

G01V 3/00

US Classification:

324309, 324307

Abstract:

A system and method for determining the temporal resolution of a tomographic imaging device uses an apparatus to drive one or more dynamic phantoms composed of multiple materials. The apparatus is placed at or near the isocenter of the imaging device and the one or more phantoms are moved to produce a plurality of dynamic features, each having a specified frequency. The dynamic features are imaged with the device and the acquired image data corresponding to the dynamic features is analyzed to determine a temporal modulation transfer value at each of the known specified frequencies. The temporal resolution of the imaging device is determined using these temporal modulation transfer values.

US Patent:

20060229641, Oct 12, 2006

Filed:

Jan 27, 2006

Appl. No.:

11/307231

Inventors:

Rajiv Gupta - Wayland MA, US
Steven Barrett - Cambridge, GB
Nevan Hanumara - Kingston RI, US
Jo-Anne Shepard - Dover MA, US
Alexander Slocum - Bow NH, US
Conor Walsh - Dublin, IE

International Classification:

A61B 19/00

US Classification:

606130000

Abstract:

Methods and devices are provided for guiding and inserting a tool into an object, such as tissue. In an exemplary embodiment, a guidance and insertion device is provided that can be remotely controlled to adjust an insertion trajectory of a tool, and to advance the tool into tissue to a desired penetration depth. The tool can be, for example, a biopsy device, a brachytherapy device, or a lumpectomy device. The device can be configured for use with an imaging apparatus, such as computed tomography (CT) images, to allow the device and tool to be operated while viewing the device positioned in relation to a target surgical site. The device can also be configured to be positioned directly on a patient, so as to passively compensate for respiratory chest motion, and it can include features to passively compensate for needle oscillation. In other exemplary embodiments, the device can be entirely disposable.

US Patent:

20190206652, Jul 4, 2019

Filed:

Aug 15, 2017

Appl. No.:

16/325936

Inventors:

- Cambridge MA, US
- Somerville MA, US
Richard C. Lanza - Brookline MA, US
George Barbastathis - Boston MA, US
Rajiv Gupta - Wayland MA, US
Jonah Jacob - Brookline MA, US

Assignee:

Massachusetts Institute of Technology - Cambridge MA
Science Reseach Laboratory, Inc. - Somerville MA

International Classification:

H01J 35/06
G01N 23/044
H01L 21/66

Abstract:

System and method for imaging an integrated circuit (IC). The imaging system comprises an x-ray source including a plurality of spatially and temporally addressable electron sources, an x-ray detector arranged such that incident x-rays are oriented normal to an incident surface of the x-ray detector and a three-axis stage arranged between the x-ray source and the x-ray detector, the three-axis stage configured to have mounted thereon an integrated circuit through which x-rays generated by the x-ray source pass during operation of the imaging system. The imaging system further comprises at least one controller configured to move the three-axis stage during operation of the imaging system and selectively activate a subset of the electron sources during movement of the three-axis stage to acquire a set of intensity data by the x-ray detector as the three-axis stage moves along a three-dimensional trajectory.

US Patent:

20190010076, Jan 10, 2019

Filed:

Jun 29, 2018

Appl. No.:

16/024086

Inventors:

- Providence RI, US
Rajiv GUPTA - Wayland MA, US
Avilash CRAMER - Lynnfield MA, US
Christopher BULL - Rehoboth MA, US
Paul WALTZ - Seekonk MA, US
Angus KINGON - Providence RI, US

International Classification:

C03B 37/012
G02B 6/08
B29C 43/00
G01T 1/20
B29C 43/58
B29D 11/00
B29K 505/02
B29K 105/16
B29K 77/00
B29K 27/12
B29K 25/00
B29C 43/18
B29K 505/08
B29L 11/00
B82Y 15/00
B29K 23/00

Abstract:

A method and apparatus to manufacture a coherent bundle of scintillating fibers is disclosed. A method includes providing a collimated bundle having a glass preform with capillaries therethrough known in the industry as a glass capillary array, and infusing the glass capillary array with a scintillating polymer or a polymer matrix containing scintillating nanoparticles.

US Patent:

20180259654, Sep 13, 2018

Filed:

Sep 27, 2016

Appl. No.:

15/760483

Inventors:

- Cambridge MA, US
Cody Andrew Dennett - Somerville MA, US
Sara Elizabeth Ferry - Cambridge MA, US
Rajiv Gupta - Wayland MA, US

International Classification:

G01T 1/06
G01T 1/10
A61N 5/10

Abstract:

An implantable dosimeter uses salt crystals such as NaCl or KCl, or other materials that vary in color as a function of incident, ionizing radiation. The color change of the salts may occur through the creation of F-centers, where electrons become trapped in crystal defects (e.g., halide vacancies) and absorb light at certain wavelengths. Vacancies in the salt crystals absorb photons at precise wavelengths. Thus, the change in color can be correlated to the integrated dose in an implantation site. The salt crystals may be optically coupled to optical fibers or the like for remote measurement of color using, e.g., a spectrometer and a computer system. In this manner, the dosage of ionizing radiation can be measured in vivo with a fault tolerant, passively integrating dosimeter.

US Patent:

20170362114, Dec 21, 2017

Filed:

Jun 19, 2017

Appl. No.:

15/626784

Inventors:

- Providence RI, US
Rajiv Gupta - Wayland MA, US
Avilash Cramer - Lynnfield MA, US
Christopher Bull - Rehoboth MA, US
Paul Waltz - Seekonk MA, US
Angus Kingon - Providence RI, US

International Classification:

C03B 37/012
G01T 1/20
B29C 43/00
B82Y 15/00
B29K 27/12

Abstract:

A method and apparatus to manufacture a coherent bundle of scintillating fibers is disclosed. A method includes providing a collimated bundle having a glass preform with capillaries therethrough known in the industry as a glass capillary array, and infusing the glass capillary array with a scintillating polymer or a polymer matrix containing scintillating nanoparticles.

US Patent:

20170248532, Aug 31, 2017

Filed:

Oct 29, 2015

Appl. No.:

15/517122

Inventors:

- Cambridge MA, US
- Boston MA, US
Rajiv Gupta - Wayland MA, US
Adam Pan - New Haven CT, US

International Classification:

G01N 23/083
H01J 35/14
G01T 1/24
H01J 35/06
G01N 23/04
G21K 1/04

Abstract:

For each X-ray path through a tissue, numerous trials are conducted. In each trial, X-ray photons are emitted along the path until a Geiger-mode avalanche photodiode “clicks”. A temporal average—i.e., the average amount of time elapsed before a “click” occurs—is calculated. This temporal average is, in turn, used to estimate a causal intensity of X-ray light that passes through the tissue along the path and reaches the diode. Based on the causal intensities for multiple paths, a computer generates computed tomography (CT) images or 2D digital radiographic images. The causal intensities used to create the images are estimated from temporal statistics, and not from conventional measurements of intensity at a pixel. X-ray dosage needed for imaging is dramatically reduced as follows: a “click” of the photodiode triggers negative feedback that causes the system to halt irradiation of the tissue along a path, until the next trial begins.