Raman M Shah

US Patent:

20060242740, Oct 26, 2006

Filed:

Aug 10, 2005

Appl. No.:

11/201562

Inventors:

Charles Collier - San Marino CA, US
Seung-Yong Jung - Seoul, KR
Hyungil Jung - Pasadena CA, US
Chiraj Dalal - Pasadena CA, US
Steven Kuntz - Pasadena CA, US
Raman Shah - Pasadena CA, US

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

C30B 25/12

US Classification:

977715000

Abstract:

A method for forming one or more nano-sized patterns using one or more molecule species overlying a substrate structure. In a preferred embodiment, the pattern or patterns relate to an array of biological molecules (e.g., DNA, small molecule(s), protein(s), ligand(s)). The method applies a probe tip (e.g., atomic force microscope probe (AFM probe)) within a vicinity of a first spatial region of a surface region of a substrate member, which is characterized by a first characteristic, e.g., hydrophobic, hydrophilic, partially hydrophobic, partially hydrophilic. In a specific embodiment, the probe tip is in a direction (e.g., normal, at an angle toward) toward the spatial region on the surface region. The method includes transferring one of more of a plurality of molecules characterized by a second characteristic through a fluid medium comprising one or more surfactant species (e.g., detergent) overlying the spatial region via the probe tip provided within the vicinity of the spatial region of the surface region. In a preferred embodiment, the one or more surfactant species causes one or more of the plurality of molecules characterized by the second characteristic to be deposited overlying the first spatial region. In a preferred embodiment, the first characteristic is different from the second characteristic.