Randall Scott Reiserer from Pleasantville, TN, age 59

Us Patents

Bioreactors With Multiple Chambers
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US Patent:

7977089, Jul 12, 2011
Filed:

Aug 27, 2003
Appl. No.:

10/525549
Inventors:

John P. Wikswo - Brentwood TN, US
Franz J. Baudenbacher - Franklin TN, US
David Cliffel - Nashville TN, US
Frederick R. Haselton - Nashville TN, US
Eugene J. Leboeuf - Franklin TN, US
Ales Prokop - Franklin TN, US
Randall S. Reiserer - Nashville TN, US
Mark A. Stremler - Franklin TN, US
Assignee:

Vanderbilt University - Nashville TN
International Classification:

C12M 1/22
C12M 3/00
C12M 1/34
US Classification:

4353052, 4352887, 435808, 4352884, 4352885, 4352971, 4353051, 4352975, 2057775, 205778, 205779, 20440301
Abstract:

A bioreactor for cultivating living cells in a liquid medium. In one embodiment of the present invention, the bioreactor has a first substrate having a first surface and an opposite second surface, defining a chamber therebetween for receiving the cells and the liquid medium. The bioreactor further has a barrier dividing the chamber into a first subchamber and a second subchamber, wherein the barrier has a porosity to allow the first subchamber and the second subchamber in fluid communication and allow at least one predetermined type of cells to permeate between the first subchamber and the second subchamber.

Capillary Perfused Bioreactors With Multiple Chambers
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US Patent:

8003378, Aug 23, 2011
Filed:

Mar 5, 2009
Appl. No.:

12/398825
Inventors:

John P. Wikswo - Brentwood TN, US
Franz J. Baudenbacher - Franklin TN, US
Ales Prokop - Nashville TN, US
Eugene LeBoeuf - Franklin TN, US
Chang Y. Chung - Franklin TN, US
David E. Cliffel - Nashville TN, US
Frederick R. Haselton - Nashville TN, US
William H. Hofmeister - Nashville TN, US
Charles P. Lin - Brentwood TN, US
Lisa J. McCawley - Nashville TN, US
Randall S. Reiserer - Nashville TN, US
Mark A. Stremler - Franklin TN, US
Assignee:

Vanderbilt University - Nashville TN
International Classification:

C12M 1/00
US Classification:

4352891
Abstract:

A bioreactor for cultivating living cells in a liquid medium. In one embodiment of the present invention, the bioreactor includes a first substrate having a first surface, an opposite second surface and edges. The bioreactor further includes a second substrate having a first surface and an opposite second surface, defining a cavity with a bottom surface, where the bottom surface is located therebetween the first surface and the second surface. The first surface of the first substrate is received by the second surface of the second substrate to cover the cavity so as to form a channel for receiving cells and a liquid medium. In forming the bioreactor, the channel is sized to allow the growth of a layer of cells on a biocompatible coating layer and a flow of liquid in the channel. The flow of liquid is controlled so as to provide a known shear force to the layer of cells. The flow of liquid can be further controlled so as to provide an environment that simulates a vascular space in the channel.

Bioreactors With An Array Of Chambers And A Common Feed Line
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US Patent:

8129179, Mar 6, 2012
Filed:

Aug 27, 2003
Appl. No.:

10/525538
Inventors:

John F. Wikswo - Brentwood TN, US
David Cliffel - Nashville TN, US
Eugene J. Leboeuf - Franklin TN, US
Randall S. Reiserer - Nashville TN, US
Assignee:

Vanderbilt University - Nashville TN
International Classification:

C12M 1/00
C12M 3/00
C12M 1/34
C12M 1/22
US Classification:

4353052, 4352883, 4352884, 4352885, 4352891, 4352975, 4353051, 4352873
Abstract:

A bioreactor () for cultivating living cells in a liquid medium. In one embodiment, the bioreactor () has a substrate () having a first surface and an opposite second surface, defining a channel () therein, and a plurality of chambers () formed in the substrate, wherein each of the plurality of chambers () is adapted for receiving cells in a liquid medium and formed with an open end (), an opposite closed end () and side walls, the open end () and the closed end () defining a depth, d, therebetween for the corresponding chamber (), the sidewalls defining a width, w, therebetween for the corresponding chamber (). As such formed, each chamber () is in fluid communication with the channel () through the open end of the chamber (), and at least two of the plurality of chambers () have depths or widths the same or different form each other.

Individual Utility Belt Section
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US Patent:

20030042284, Mar 6, 2003
Filed:

Aug 28, 2001
Appl. No.:

09/939619
Inventors:

Randall Reiserer - Nashville TN, US
International Classification:

A45F005/00
US Classification:

224/660000, 224/674000
Abstract:

A strap-like clip-on accessory retainer or holder for attachment to the user's belt or waistband for the convenience of carrying handy tools, such as knives, pouches for holding small items, tapes, etc. like a utility belt. The accessory retainer or holder allows belt accessories to be attached to the waistband of trousers, shorts, skirts, etc., with or without a belt, as well as to any other wearable or non-wearable material having a thin edge. The inventive strap-like accessory retainer or holder can accommodate several accessories at once and can, therefore, be used to assemble semi-permanent “kits” of accessories that are commonly used together in particular applications. With the belt's clip-on or clamp-on construction, it can supply the secondary function of a waist belt (to harness accessories) without the necessity of serving the primary function (to adjust waistband circumference).

Individual Utility Belt Section
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US Patent:

20040000571, Jan 1, 2004
Filed:

Jun 30, 2003
Appl. No.:

10/608638
Inventors:

Randall Reiserer - Nashville TN, US
Ronald Reiserer - Nashville TN, US
International Classification:

A45C001/04
A45F003/00
F41C033/02
F42B039/02
US Classification:

224/660000
Abstract:

A clip-on utility carrier for attachment to the user's waistband for the convenience of carrying handy tools, such as knives, pouches for holding small items, tapes, etc. The utility carrier allows belt accessories to be attached to the waistband of trousers, shorts, skirts, etc., with or without a belt, as well as to any other wearable or non-wearable material having a thin edge. The inventive utility carrier can accommodate several accessories at once and can, therefore, be used to assemble semi-permanent “kits” of accessories that are commonly used together in particular applications. With the utility carrier's clip-on or clamp-on construction, it can supply the secondary function of a waist belt (to harness accessories) without the necessity of serving the primary function (to adjust waistband circumference).

Capillary Perfused Bioreactors With Multiple Chambers
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US Patent:

20060141607, Jun 29, 2006
Filed:

Aug 27, 2003
Appl. No.:

10/525559
Inventors:

John Wikswo - Brentwood TN, US
Franz Baudenbacher - Franklin TN, US
Alex Prokop - Nashville TN, US
Eugene Leboeuf - Franklin TN, US
Chang Chung - Franklin TN, US
David Cliffel - Nashville TN, US
Frederick Haselton - Nashville TN, US
William Hofmeister - Nashville TN, US
Charles Lin - Brentwood TN, US
Lisa McCawley - Nashville TN, US
Randall Reiserer - Nashville TN, US
Mark Stremler - Franklin TN, US
International Classification:

C12M 1/34
US Classification:

435287100
Abstract:

A bioreactor for cultivating living cells in a liquid medium. In one embodiment of the present invention, the bioreactor includes a first substrate having a first surface, an opposite second surface and edges. The bioreactor further includes a second substrate having a first surface and an opposite second surface, defining a cavity with a bottom surface, where the bottom surface is located therebetween the first surface and the second surface. The first surface of the first substrate is received by the second surface of the second substrate to cover the cavity so as to form a channel for receiving cells and a liquid medium. In forming the bioreactor, the channel is sized to allow the growth of a layer of cells on a biocompatible coating layer and a flow of liquid in the channel. The flow of liquid is controlled so as to provide a known shear force to the layer of cells. The flow of liquid can be further controlled so as to provide an environment that simulates a vascular space in the channel.

Bioreactors With Multiple Chambers
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US Patent:

20110294202, Dec 1, 2011
Filed:

May 26, 2011
Appl. No.:

13/116174
Inventors:

John P. Wikswo - Brentwood TN, US
Franz J. Baudenbacher - Franklin TN, US
David Cliffel - Nashville TN, US
Frederick R. Haselton - Nashville TN, US
Eugene J. Leboeuf - Franklin TN, US
Ales Prokop - Franklin TN, US
Randall S. Reiserer - Nashville TN, US
Mark A. Stremler - Franklin TN, US
Assignee:

VANDERBILT UNIVERSITY - Nashville TN
International Classification:

C12M 1/34
US Classification:

4352879, 4352887
Abstract:

A bioreactor for cultivating living cells in a liquid medium. In one embodiment of the present invention, the bioreactor has a first substrate having a first surface and an opposite second surface, defining a chamber therebetween for receiving the cells and the liquid medium. The bioreactor further has a barrier dividing the chamber into a first subchamber and a second subchamber, wherein the barrier has a porosity to allow the first subchamber and the second subchamber in fluid communication and allow at least one predetermined type of cells to permeate between the first subchamber and the second subchamber.

Capillary Perfused Bioreactors With Multiple Chambers
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US Patent:

20120003729, Jan 5, 2012
Filed:

Jul 1, 2011
Appl. No.:

13/175659
Inventors:

John P. Wikswo - Brentwood TN, US
Franz J. Baudenbacher - Franklin TN, US
Ales Prokop - Franklin TN, US
Eugene J. Leboeuf - Franklin TN, US
Chang Y. Chung - Franklin TN, US
David Cliffel - Nashville TN, US
Frederick R. Haselton - Nashville TN, US
William H. Hofmeister - Nashville TN, US
Charles P. Lin - Brentwood TN, US
Lisa J. McCawley - Nashville TN, US
Randall S. Reiserer - Nashville TN, US
Mark A. Stremler - Franklin TN, US
Assignee:

VANDERBILT UNIVERSITY - Nashville TN
International Classification:

C12M 1/34
C12M 1/12
C12M 1/04
C12M 1/00
US Classification:

4352887, 4352891, 4352971, 4352871
Abstract:

A bioreactor for cultivating living cells in a liquid medium. In one embodiment of the present invention, the bioreactor includes a first substrate having a first surface, an opposite second surface and edges. The bioreactor further includes a second substrate having a first surface and an opposite second surface, defining a cavity with a bottom surface, where the bottom surface is located therebetween the first surface and the second surface. The first surface of the first substrate is received by the second surface of the second substrate to cover the cavity so as to form a channel for receiving cells and a liquid medium. In forming the bioreactor, the channel is sized to allow the growth of a layer of cells on a biocompatible coating layer and a flow of liquid in the channel. The flow of liquid is controlled so as to provide a known shear force to the layer of cells. The flow of liquid can be further controlled so as to provide an environment that simulates a vascular space in the channel.