Randy Keith Davis

US Patent:

8324914, Dec 4, 2012

Filed:

Feb 8, 2010

Appl. No.:

12/658604

Inventors:

Roger Chen - Saratoga CA, US
Randy Davis - Pleasanton CA, US

Assignee:

Genia Technologies, Inc. - Mountain View CA

International Classification:

G01N 27/00

US Classification:

324717, 324713

Abstract:

Techniques for characterizing a molecule are described herein. In one example, a portion of the molecule is trapped in a nanopore, a variable voltage is applied across the nanopore until the trapped portion of molecule is moved within the nanopore, and the molecule is characterized based on the electrical stimulus required to affect movement of at least a portion of the trapped portion of the molecule within the nanopore.

US Patent:

8461854, Jun 11, 2013

Filed:

Sep 15, 2012

Appl. No.:

13/620973

Inventors:

Roger Chen - Saratoga CA, US
Randy Davis - Pleasanton CA, US

Assignee:

Genia Technologies, Inc. - Mountain View CA

International Classification:

G01R 27/08

US Classification:

324717, 324692

Abstract:

Techniques for characterizing a molecule are described herein. In one example, a portion of the molecule is trapped in a nanopore, a variable voltage is applied across the nanopore until the trapped portion of molecule is moved within the nanopore, and the molecule is characterized based on the electrical stimulus required to affect movement of at least a portion of the trapped portion of the molecule within the nanopore.

US Patent:

7261638, Aug 28, 2007

Filed:

May 24, 2005

Appl. No.:

11/136755

Inventors:

Randy R. Davis - Thousand Oaks CA, US
Richard Shum - Sheung Shui, N.T., HK

International Classification:

A63D 5/00

US Classification:

473 55, 473125, 473596

Abstract:

A bowling practice device for regularizing and perfecting bowling technique. An aerodynamically designed hollow body includes an outer wall and a cylindrical inner wall. The opposed ends of the outer wall taper to meet the cylindrical inner wall. The outer wall preferably comprises a plurality of foam panels, one of which includes at least two finger holes suitable for personalization to the hand of the bowler.

US Patent:

20110192723, Aug 11, 2011

Filed:

Feb 8, 2010

Appl. No.:

12/658601

Inventors:

Roger Chen - Saratoga CA, US
Randy Davis - Pleasanton CA, US

International Classification:

G01N 27/447
G01N 33/50
B82Y 5/00

US Classification:

204451, 204601, 977902

Abstract:

Techniques for manipulating a molecule in a nanopore embedded in a lipid bilayer are described. In one example, an acquiring electrical stimulus level is applied across a lipid bilayer wherein a region of the lipid bilayer containing the nanopore is characterized by a resistance and wherein the acquiring electrical stimulus level tends to draw the molecule from a surrounding fluid into the nanopore, a change in the resistance of the lipid bilayer resulting from the acquisition of at least a portion of a molecule into the nanopore is detected, the acquiring electrical stimulus level is changed to a holding electrical stimulus level wherein the portion of the molecule remains in the nanopore upon the changing of the acquiring electrical stimulus level to the holding electrical stimulus level.

US Patent:

20110193249, Aug 11, 2011

Filed:

Feb 8, 2010

Appl. No.:

12/658591

Inventors:

Roger Chen - Saratoga CA, US
Randy Davis - Pleasanton CA, US

International Classification:

B29C 67/24

US Classification:

264 4

Abstract:

Techniques for forming a nanopore in a lipid bilayer are described herein. In one example, an agitation stimulus level such as an electrical agitation stimulus is applied to a lipid bilayer wherein the agitation stimulus level tends to facilitate the formation of nanopores in the lipid bilayer. In some embodiments, a change in an electrical property of the lipid bilayer resulting from the formation of the nanopore in the lipid bilayer is detected, and a nanopore has formed in the lipid bilayer is determined based on the detected change in the lipid bilayer electrical property.

US Patent:

20110287414, Nov 24, 2011

Filed:

Feb 8, 2010

Appl. No.:

12/658603

Inventors:

Roger Chen - Saratoga CA, US
Randy Davis - Pleasanton CA, US

International Classification:

C12Q 1/68
G06F 19/00
G01N 33/573
G01N 30/00
C12M 1/34
G01N 33/00
G01N 27/04
G01N 27/22

US Classification:

435 611, 73 6161, 702 19, 422 69, 4352871, 4352872, 436 86, 435 74, 435 61

Abstract:

Techniques for identifying a portion of a molecule are described herein. In one example, multiple electrical measurements associated with a molecule are acquired, wherein each of the multiple electrical measurements corresponds to a discrete position of the molecule within a nanopore. The multiple electrical measurements are correlated with one or more sequences of electrical measurements corresponding to a possible structure of the molecule. The portion of molecule is determined to include the possible structure of the molecule based on the correlation.

US Patent:

20120052188, Mar 1, 2012

Filed:

Feb 8, 2010

Appl. No.:

12/658602

Inventors:

Roger Chen - Saratoga CA, US
Randy Davis - Pleasanton CA, US

International Classification:

C23C 16/52
B29C 71/04
B05C 9/12
B05D 5/12

US Classification:

427 8, 427 77, 427532, 118712

Abstract:

Techniques for assembling a lipid bilayer on a substantially planar solid surface are described herein. In one example, a lipid material such as a lipid suspension is deposited on a substantially planar solid surface, a bubble filled with fast diffusing gas molecules is formed on the solid surface, and the gas molecules are allowed to diffuse out of the bubble to form a lipid bilayer on the solid surface.

US Patent:

20140014513, Jan 16, 2014

Filed:

May 13, 2013

Appl. No.:

13/893142

Inventors:

Randy Davis - Pleasanton CA, US

Assignee:

Genia Technologies, inc. - Mountain View CA

International Classification:

G01N 27/447

US Classification:

204451, 204601, 977781, 977924

Abstract:

Techniques for characterizing a molecule are described herein. In one example, a portion of the molecule is trapped in a nanopore, a variable voltage is applied across the nanopore until the trapped portion of molecule is moved within the nanopore, and the molecule is characterized based on the electrical stimulus required to affect movement of at least a portion of the trapped portion of the molecule within the nanopore.