Randy T Jacobs

US Patent:

20040219177, Nov 4, 2004

Filed:

Apr 29, 2003

Appl. No.:

10/426493

Inventors:

Randy Jacobs - Murrieta CA, US

International Classification:

A61K031/16
A61K007/00

US Classification:

424/401000, 514/625000

Abstract:

The depleted skin barrier replenishing compositions and methods of applying them involves the use of two separate skin moisturizing therapy compositions, each of which is incorporated into a pharmaceutically acceptable vehicle that may be applied in various combinations, either individually, together or sequentially with an interval of several hours between each application. The first therapeutic composition utilizes a synthetic, non-animal derived analogue of ceramide as a ceramide replacement component, and free fatty acids, in a 3:1 mole ratio. The ceramide replacement component may be bishydroxyethyl biscetyl malonamide. The second therapeutic composition utilizes a plant derived analogue of cholesterol as a cholesterol replacement component, and free fatty acids, in a 3:1 mole ratio. The cholesterol replacement component may be phytosterols.