Raymond S Parker

US Patent:

20050197299, Sep 8, 2005

Filed:

Aug 31, 2001

Appl. No.:

10/344112

Inventors:

Robert Babine - Franklin MA, US
Jason Lamar - Indianapolis IN, US
Nancy Snyder - Lizton IN, US
Xicheng Sun - Superior CO, US
Mark Tebbe - Hamburg, DE
Frantz Victor - Indianapolis IN, US
Yvonne Yip - Indianapolis IN, US
Ivan Collado - Madrid, ES
Cristina Garcia-Paredes - Madrid, ES
Raymond Parker - Doylestown PA, US
Ling Jing - Carmel IN, US
Deqi Guo - Carmel IN, US
John Glass - Indianapolis IN, US

International Classification:

A61K038/05
A61K038/04
C07K005/06
C07K005/04

US Classification:

514018000, 514019000, 514217110, 514317000, 514423000, 530331000, 548537000, 540607000, 546226000, 548953000, 514210170

Abstract:

The present invention relates to peptidomimetic compounds useful as protease inhibitors, particularly as serine protease inhibitors and more particularly as hepatitis C NS3 protease inhibitors; intermediates thereto; their preparation including novel steroselective processes to intermediates. The invention is also directed to pharmaceutical compositions and to methods for using the compounds for inhibiting HCV protease or treating a patient suffering from an HCV infection or physiological condition related to the infection. Also provided are pharmaceutical combinations comprising, in addition to one or more HCV serine protease inhibitors, one or more interferons exhibiting anti-HCV activity and/or one or more compounds having anti HCV activity and a pharmaceutically acceptable carrier, and methods for treating or preventing a HCV infection in a patient using the compositions. The present invention is also directed to a kit or pharmaceutical pack for treating or preventing HCV infection in a patient.

US Patent:

58194576, Oct 13, 1998

Filed:

Jul 5, 1996

Appl. No.:

8/675920

Inventors:

Raymond J. Parker - Attleboro MA

International Classification:

A47G 700

US Classification:

40657

Abstract:

A support (12) has a playing field (14) demarked thereon with a plurality of sets (16, 18, 20, 26, 28, 30) of attachment devices. Each set has an attachment devices in the form of a hook member (24) for each team of a league for removable attachment of a team designator (40) unique to the respective team of the league. Separate attachment devices (34, 36) are provided for the winner of each league and the ultimate winner of the World Series (38).