Raymond Jason Rodriguez

US Patent:

6680425, Jan 20, 2004

Filed:

Nov 29, 1999

Appl. No.:

09/450515

Inventors:

Raymond L. Rodriguez - Davis CA

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

C12N 504

US Classification:

800287, 4353201, 435419, 536 236, 536 241

Abstract:

A chimeric plant promoter which is responsive to sugar depletion or deprivation is disclosed. The promoter includes a promoter element and, carried in the element, a heterologous sequence from the rice Amy3D that is responsive to sugar depletion. Also disclosed is a plant transfecting vector containing the sequence, and plant cell transfected with the vector.

US Patent:

6781044, Aug 24, 2004

Filed:

Aug 17, 2001

Appl. No.:

09/932328

Inventors:

Raymond L. Rodriguez - Davis CA
Ning Huang - Davis CA

Assignee:

Ventria Bioscience - Sacramento CA

International Classification:

C12N 1582

US Classification:

8003202, 800287, 800300, 800278, 435193, 435204, 435209, 4354301, 435468

Abstract:

A plant transformation vector for transforming host plant cells with a chimeric selectable marker gene is disclosed. The gene includes, operatively linked in sequence in a 5â to 3â direction, (i) a DNA promoter sequence from the rice beta-glucanase 9 (gns9) gene; (ii) a selectable marker gene, and (iii) a 3â untranslated terminator region. Also disclosed are a vector pair containing the transformation vector, a method of obtaining transformed monocots whose seeds produce a selected heterologous protein during sed germination, and a plant whose cells are transformed with the chimeric selectable marker gene.

US Patent:

6919493, Jul 19, 2005

Filed:

Jul 25, 2002

Appl. No.:

10/206654

Inventors:

Raymond L. Rodriguez - Davis CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

C12N005/10
C12N015/82
C12N015/90
C07H021/04

US Classification:

800278, 4353201, 435419, 536 241

Abstract:

A chimeric plant promoter which is responsive to sugar depletion or deprivation is disclosed. The promoter includes a promoter element and, carried in the element, a heterologous sequence from the rice Amy3D that is responsive to sugar depletion. Also disclosed is a plant transfecting vector containing the sequence, and plant cell transfected with the vector.

US Patent:

6991824, Jan 31, 2006

Filed:

Feb 14, 2002

Appl. No.:

10/077381

Inventors:

Ning Huang - Davis CA, US
Raymond L. Rodriguez - Davis CA, US
Frank E. Hagie - Sacramento CA, US

Assignee:

Ventria Bioscience - Sacramento CA

International Classification:

A21D 2/26

US Classification:

426622, 426629

Abstract:

The invention is directed to food and food additive compositions comprising one or more human milk proteins produced in the seeds of a transgenic plant and methods of making the same. The invention is further directed to improved infant formula comprising such food supplement composition.

US Patent:

7045681, May 16, 2006

Filed:

Oct 18, 2002

Appl. No.:

10/274748

Inventors:

Raymond L. Rodriguez - Davis CA, US
Bruce R. Thomas - Davis CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

C12N 15/82
C12N 15/90
C12N 15/29

US Classification:

800278, 8003202, 800317

Abstract:

The present invention relates to a method for producing a gene product by expressing a gene encoding said gene product in angiosperm host cells, which method comprises: a) constructing a vector expressible in angiosperm host cells, said vector comprising a promoter region derived from an amylase gene selected from SBAmyA, SBAmyB, SBAmyC genes or SBAmyD of the sugar beet and a gene encoding a desired gene product; b) transforming a compatible angiosperm host cell with said vector; c) cultivating the resulting transformant host cell to a sugar-depleted or sugar-free condition to promote the expression of said gene under the control of such promoter region; and d) recovering the product of the expressed gene. The sugar beet gene when incorporated into a dicot seed or plant has improved biological properties. The gene sequences and the products thereof are claimed.

US Patent:

7417178, Aug 26, 2008

Filed:

Aug 12, 2003

Appl. No.:

10/639835

Inventors:

Ning Huang - Davis CA, US
Raymond L. Rodriguez - Davis CA, US
Frank E. Hagie - Sacramento CA, US

Assignee:

Ventria Bioscience - Sacramento CA

International Classification:

C12N 15/82
A01H 5/00
C07H 21/04

US Classification:

800288, 800287, 800298, 8003202, 536 241

Abstract:

The invention is directed to seed and seed extract compositions containing levels of a human milk protein between 3-40% or higher of the total protein weight of the soluble protein extractable from the seed. Also disclosed is a method of producing the seed with high levels of extractable human milk protein. The method includes transforming a monocotyledonous plant with a chimeric gene having a protein-coding sequence encoding a protein normally present in human milk under the control of a seed maturation-specific promoter. The method may further includes a leader DNA sequence encoding a monocot seed-specific transit sequence capable to target a linked milk protein to a storage body.

US Patent:

7718851, May 18, 2010

Filed:

Apr 21, 2008

Appl. No.:

12/148779

Inventors:

Ning Huang - Davis CA, US
Raymond L. Rodriguez - Davis CA, US
Frank E. Hagie - Sacramento CA, US

Assignee:

Ventria Bioscience - Sacramento CA

International Classification:

C12N 15/82
C12P 21/00
A01H 5/00

US Classification:

800288, 435 691, 800298

Abstract:

The invention is directed to seed and seed extract compositions containing levels of a human milk protein between 3-40% or higher of the total protein weight of the soluble protein extractable from the seed. Also disclosed is a method of producing the seed with high levels of extractable human milk protein. The method includes transforming a monocotyledonous plant with a chimeric gene having a protein-coding sequence encoding a protein normally present in human milk under the control of a seed maturation-specific promoter. The method may further includes a leader DNA sequence encoding a monocot seed-specific transit sequence capable to target a linked milk protein to a storage body.

US Patent:

7829277, Nov 9, 2010

Filed:

Feb 15, 2005

Appl. No.:

10/591097

Inventors:

Raymond Rodriguez - Davis CA, US
Mark Jesus Mendoza Magbanua - San Francisco CA, US

Assignee:

The Regents of the University of California - Oakland CA

International Classification:

C12Q 1/68
C07H 21/02
C07H 21/04

US Classification:

435 6, 536 235, 536 2431

Abstract:

Gene expression profiles produced in response to lunasin exposure, wherein such gene expression profiles correlate with anti-neoplastic activity, methods for using such expression profiles for screening potential anti-neoplastic agents, and methods for treatment and monitoring of a subject having a neoplastic disease.