- Indianola PA, US Reginald BRADLEY - Bedminster NJ, US Eric DANN - Safety Harbor FL, US Thomas DANN - Palm Harbor FL, US Courtney C. HAYNES - Dunedin FL, US Gerard MEISEL - Budd Lake NJ, US Renee NELSON - Brandon FL, US Soundarya VAITHIANATHAN - Parsippany NJ, US Emanuel VIZZOTTI - Millburn NJ, US Reinhard WALTER - Morristown NJ, US
Provided are topical analgesic spray compositions and topical analgesic spray concentrates containing menthol and camphor in high concentrations. The present disclosure also provides organoleptic compositions for use in the topical analgesic spray compositions and concentrates to provide enhanced sensory experience and long-lasting pain-relief.
- Indianola PA, US Emanuel VIZZOTTI - Millburn NJ, US Thomas DANN - Palm Harbor FL, US Renee NELSON - Brandon FL, US Courtney C. HAYNES - Dunedin FL, US Soundarya VAITHIANATHAN - Parsippany NJ, US Reginald BRADLEY - Bedminster NJ, US Reinhard WALTER - Morristown NJ, US Gerard MEISEL - Budd Lake NJ, US
Provided are topical analgesic gel compositions having relatively high payloads of menthol and camphor by micro-emulsion technology and methods of preparing topical analgesic gel compositions having relatively high payloads of menthol and camphor. Topical analgesic gel compositions may include from 12 to 16 wt. % menthol; from 4 to 8 wt. % camphor; from 0.1 to 2 wt. % carbomer; and 60 to 70 wt. % solvent. Topical analgesic gel compositions can have a viscosity from 60,000 to 110,000 centipoise.
- Indianola PA, US Emanuel VIZZOTTI - Millburn NJ, US Thomas DANN - Palm Harbor FL, US Renee NELSON - Brandon FL, US Courtney C. HAYNES - Dunedin FL, US Soundarya VAITHIANATHAN - Parsippany NJ, US Reginald BRADLEY - Bedminster NJ, US Reinhard WALTER - Morristown NJ, US Gerard MEISEL - Budd Lake NJ, US
International Classification:
A61K 31/4164 A61K 31/125 A61K 31/045 A61K 47/44
Abstract:
Provided are topical analgesic compositions and methods of preparing topical analgesic compositions comprising a stable nano-encapsulating matrix film. The topical analgesic compositions and methods of preparing topical analgesic compositions may be suited for roll-on applicators. Topical analgesic compositions may include 12 to 16 wt. % menthol; 4 to 8 wt. % camphor; 2 to 15 wt. % film-forming polymer; and 50 to 70 wt. % solvent. To be used in a roll-on applicator, the topical analgesic composition has a viscosity from 800 to 1400 centipoise.
- Whippany NJ, US - Largo FL, US Heidi Graham - Charlottesville VA, US Nanhye Kim - New Providence NJ, US Tom Meyer - Germantown TN, US David Reynolds - Ooltewah TN, US Jerry Vancleave - Lakeland TN, US Eric Dann - Safety Harbor FL, US Thomas Dann - Palm Harbor FL, US Renee Nelson - Brandon FL, US Brian Dann - Clearwater FL, US
The present disclosure relates to, inter alia, a method of making a whipped formulation and the formulation. The method comprises: selecting an amount of a gas propellant co-mingled with one or more active agents. The gas propellant is dispersed in the formulation, and the formulation is filled under pressure into a package, which may be pressurized. The package has a selected amount of pressure (“pre-gas or cut-bag pressure”). The pressure maintains the gas propellant dispersed in the formulation and the pressurized package is under sufficient pressure such that the formulation may be expelled as a whipped formulation upon application of external force on said formulation in said package. The whipped formulation is characterized by providing a desired sensory impact to a user.
Stephen BALDWIN - Germantown TN, US Scott CARPENTER - ARLINGTON TN, US Heidi GRAHAM - Charlottesville VA, US Nanhye KIM - Germantown TN, US Tom MEYER - Germantown TN, US David REYNOLDS - Collierville TN, US Jerry VANCLEAVE - Lakeland TN, US Eric DANN - Safety Harbor FL, US Thomas DANN - Palm Harbor FL, US Renee NELSON - BRANDON FL, US Brian DANN - Clearwater FL, US - Whippany NJ, US - Largo FL, US
The present disclosure relates to, inter alia, a formulation in a package. The formulation comprises one or more active agents and is co-mingled with a whipping agent prior to being filled under pressure into the package. The whipping agent is added in sufficient amounts to be dispersed in the formulation. The pressurized package is under sufficient pressure suitable to maintain the whipping agent dispersed in the formulation; and the pressurized package is under sufficient pressure to expel the formulation as a whipped formulation upon application of external force on the formulation in the package.
Stephen BALDWIN - Germantown TN, US Scott CARPENTER - Arlington TN, US Heidi GRAHAM - Charlottesville VA, US Nanhye KIM - Germantown TN, US Tom MEYER - Germantown TN, US David REYNOLDS - Collierville TN, US Jerry VANCLEAVE - Lakeland TN, US Eric DANN - Safety Harbor FL, US Thomas DANN - Palm Harbor FL, US Renee NELSON - Brandon FL, US Brian DANN - Clearwater FL, US - Whippany NJ, US - Largo FL, US
The present disclosure relates to, inter alia, a formulation in a package, the formulation comprises one or more active agents and is co-mingled with a whipping agent prior to being filled under pressure into the package. The whipping agent is added in sufficient amounts to be dispersed in the formulation. The pressurized package is under sufficient pressure suitable to maintain the whipping agent dispersed in the formulation; and the pressurized package is under sufficient pressure to expel the formulation as a whipped formulation upon application of external force on the formulation in the package.
Stabilized, Sprayable Emulsion Containing Active Agent Particles
A sprayable emulsion is provided. The emulsion can be used in the treatment of various skin conditions. The emulsion includes a hydrofluoro-based propellant, an emulsification system, an oil phase, a water phase, and active agent particles. Further, the emulsification system includes at least one nonionic emulsifier. The emulsion has a viscosity ranging from about 500 centipoise to about 10,000 centipoise and a hydrophilic to lipophilic balance (HLB) value of from about 2 to about 12. The present inventors have found that by selectively controlling the nature of the emulsification system and the viscosity of the emulsion, the active agent particles resist settling such that a substantially homogeneous distribution of the active agent particles is maintained and can be evenly sprayed onto a surface without running once applied.
Scripps ClinicScripps Clinic Obstetrics & Gynecology 9850 Genesee Ave STE 600, La Jolla, CA 92037 8584530753 (phone), 8584581002 (fax)
Education:
Medical School George Washington University School of Medicine and Health Science Graduated: 1997
Procedures:
Cesarean Section (C-Section) Colposcopy D & C Dilation and Curettage Delivery After Previous Caesarean Section Hysterectomy Myomectomy Ovarian Surgery Tubal Surgery Vaccine Administration Vaginal Delivery
Conditions:
Breast Disorders Complicating Pregnancy or Childbirth Spontaneous Abortion Abnormal Vaginal Bleeding Candidiasis of Vulva and Vagina
Languages:
English Korean Spanish
Description:
Dr. Nelson graduated from the George Washington University School of Medicine and Health Science in 1997. She works in La Jolla, CA and specializes in Obstetrics & Gynecology. Dr. Nelson is affiliated with Scripps Memorial Hospital Encinitas and Scripps Memorial Hospital La Jolla.
Kaiser Permanente Medical GroupKaiser Permanente Sacramento Medical Center 2345 Fair Oaks Blvd, Sacramento, CA 95825 9169735000 (phone), 9164806424 (fax)
Education:
Medical School University of California, San Francisco School of Medicine Graduated: 1998
Procedures:
Destruction of Benign/Premalignant Skin Lesions Sigmoidoscopy Vaccine Administration
Dr. Nelson graduated from the University of California, San Francisco School of Medicine in 1998. She works in Sacramento, CA and specializes in Family Medicine.
Sharp Community Medical GroupPulmonary Medicine & Infectious Diseases Medical Group 6699 Alvarado Rd STE 2308, San Diego, CA 92120 6194629010 (phone), 6192878165 (fax)
Education:
Medical School Saint Louis University School of Medicine Graduated: 1990
Dr. Nelson graduated from the Saint Louis University School of Medicine in 1990. She works in San Diego, CA and specializes in Pulmonary Critical Care Medicine. Dr. Nelson is affiliated with Alvarado Hospital LLC, Promise Hospital Of San Diego, Sharp Grossmont Hospital and Vibra Hospital Of San Diego.
El Rancho Elementary School Camarillo CA 1974-1975, John Dolland Elementary School Norwalk CA 1978-1980, Los Nogales Elementary School Camarillo CA 1980-1980, Los Altos Intermediate School Camarillo CA 1981-1982
Community:
Benny Esparza
Biography:
Married for 18+ yrs, mother of 3 beautiful boys ages 24, 15 & 13, Grandmother to 1 a...