Richard A George

US Patent:

7853309, Dec 14, 2010

Filed:

Mar 10, 2005

Appl. No.:

11/075667

Inventors:

Takashi Ichihara - Nagoya, JP
Toshihiro Rifu - Saitama, JP
Joao A. C. Lima - Timonium MD, US
Richard T. George - Sparks MD, US
Albert C. Lardo - Baldwin MD, US

Assignee:

Toshiba Medical Systems Corporation - Otawara-Shi
The Johns Hopkins University - Baltimore MD

International Classification:

A61B 5/05

US Classification:

600425, 600407, 600431

Abstract:

An X-ray CT apparatus comprises a blood-flow information acquisition unit, a correction value calculating unit and a blood-flow image generating unit. The blood-flow information acquisition unit obtains information of a relative blood flow rate in the myocardium of the subject based on the CT image. The correction value calculating unit obtains a correction value based on the CT image in a concentration transition period defined to be a period from immediately after start of a continuous injection of a contrast medium into the subject until the contrast medium reaching the myocardium increases and is be in a state where it can be considered that the contrast medium is saturated at a constant value. The blood-flow image generating unit generates a blood flow value image in the myocardium by correcting the information of the relative blood flow rate with the correction value.

US Patent:

8160338, Apr 17, 2012

Filed:

May 20, 2008

Appl. No.:

12/123776

Inventors:

Takashi Ichihara - Nagoya, JP
Richard T. George - Sparks MD, US
Joao A. C. Lima - Timonium MD, US
Albert C. Lardo - Baldwin MD, US

Assignee:

Toshiba Medical Systems Corporation - Otawara-shi
The Johns Hopkins University - Baltimore MD

International Classification:

G06K 9/00

US Classification:

382131, 378 4

Abstract:

An apparatus includes a transformation table acquiring unit, a blood-flow information acquisition unit and a blood-flow image generating unit. The transformation table acquiring unit obtains a transformation table for transforming unspecified information representing a concentration of a contrast medium in a myocardium into an unspecified blood flow value image based on a CT image acquired in a concentration transition period. The blood-flow information acquisition unit obtains information representing the concentration of the contrast medium based on a CT image acquired during a constant concentration period. The blood-flow image generating unit generates a blood flow value image based on the information representing the concentration of the contrast medium according to the transformation table.

US Patent:

8615116, Dec 24, 2013

Filed:

Sep 29, 2008

Appl. No.:

12/680152

Inventors:

Albert Clark Lardo - Baldwin MD, US
Richard T. George - Monkton MD, US
Joao A. C. Lima - Baltimore MD, US
Eduardo T. Marban - Beverly Hills CA, US
Takashi Ichihara - Nagoya, JP

Assignee:

The Johns Hopkins University - Baltimore MD
Toshiba Medical Systems Corporation - Otawara-shi, Tochigi-ken

International Classification:

G06K 9/00
A61B 6/00

US Classification:

382128, 382130, 382131, 378 4, 378 8

Abstract:

A computed tomography system has a support stage constructed and arranged to support a subject while under observation, an x-ray illumination system arranged proximate the support stage to illuminate the subject with x-rays, an x-ray detection system arranged proximate the support stage to detect x-rays after they pass through the subject and to provide signals based on the detected x-rays, and a data processing system in communication with the x-ray detection system to receive the signals from the x-ray detection system. The computed tomography system has a dynamic mode of operation and a scanning mode of operation. The data processing system extracts information concerning a dynamic process of the subject based on signals from both the dynamic mode and the scanning mode of operation.

US Patent:

20120155737, Jun 21, 2012

Filed:

Dec 20, 2010

Appl. No.:

12/973115

Inventors:

Takuya SAKAGUCHI - Shioya-gun, JP
Hisato Takemoto - Nasushiobara-shi, JP
Joao A. C. Lima - Baltimore MD, US
Richard T. George - Baltimore MD, US
Jeff Trost - Baltimore MD, US

Assignee:

THE JOHNS HOPKINS UNIVERSITY - Baltimore MD
TOSHIBA MEDICAL SYSTEMS CORPORATION - Otawara-shi

International Classification:

G06K 9/00
G06T 11/20
G09G 5/00

US Classification:

382132, 345635, 345442

Abstract:

In one embodiment, an image processing apparatus includes a difference image generating unit and a display controlling unit. The difference image generating unit generates a difference image by calculating a difference in a second X-ray transmission image from a first X-ray transmission image, the second X-ray transmission image being an image in which a myocardial tissue of an examined subject is not opacified and the first X-ray transmission image being an image in which the myocardial tissue of the examined subject is opacified with a contrast agent that has been injected into a coronary artery. The display controlling unit exercises control so that a predetermined display unit displays the difference image that has been generated by the difference image generating unit.

US Patent:

20130243301, Sep 19, 2013

Filed:

May 3, 2013

Appl. No.:

13/886910

Inventors:

- Otawara-shi, JP
Takashi ICHIHARA - Nagoya-shi, JP
Jingwu YAO - Buffalo Grove IL, US
Richard T. GEORGE - Baltimore MD, US
Jeff TROST - Baltimore MD, US
Omair Khwaja YOUSUF - Baltimore MD, US
Joao A. C. LIMA - Baltimore MD, US

Assignee:

Toshiba Medical Systems Corporation - Otawara-shi

International Classification:

G06T 7/00

US Classification:

382132

Abstract:

An image processing apparatus according to the present embodiment includes a correcting unit. The correcting unit identifies, based on an observation value of a residual contrast material component that is injected to a subject before a predetermined timing and remains in the subject, the residual contrast material component and a new contrast material component that is newly injected to the subject after the predetermined timing regarding a contrast material component that is included in an image, and corrects an observation value of the contrast material component included in the image.

US Patent:

20160004837, Jan 7, 2016

Filed:

Feb 17, 2014

Appl. No.:

14/767668

Inventors:

- Baltimore MD, US
Richard Thomas George - Sparks MD, US
Jung Hee Seo - Baltimore MD, US

International Classification:

G06F 19/00
A61B 5/055
A61B 8/08
A61B 5/00
A61B 6/03
A61B 8/06
A61B 6/00

Abstract:

The present invention provides a method for determining thromboembolic risk in a patient. The method includes processing functional images of a patient's heart in order to create a computational fluid dynamic (CFD) modeling of the patient's heart. Once a CFD model is obtained, various metrics can be determined to estimate the patient's risk of left ventricular thrombosis. This method is particularly suited for determining thromboembolic risk in patients having suffered a myocardial infarction. However, the method can also be applied to a broader population at risk of cardioembolic and cryptogenic stroke.

US Patent:

20150087956, Mar 26, 2015

Filed:

Dec 5, 2014

Appl. No.:

14/562220

Inventors:

- Otawara-shi, JP
- Baltimore MD, US
Jeff Trost - Baltimore MD, US
Richard T. George - Baltimore MD, US
Joao A.C. Lima - Baltimore MD, US
Omair Yousuf - Baltimore MD, US

Assignee:

Toshiba Medical Systems Corporation - Otawara-shi
The Johns Hopkins University - Baltimore MD

International Classification:

A61B 6/00

US Classification:

600407

Abstract:

An X-ray diagnostic apparatus according to the embodiment includes an X-ray tube, an X-ray detector, image generating unit generating time-series medical images of vasoganglion in a predetermined organ of a subject, region setting unit setting a first upstream and downstream region of a stenosis location in a first blood vessel in the vasoganglion on the medical images, curve generating unit generating a stenosis upstream and downstream curve indicating a change in pixel value in the time-series based on pixel values included in the first upstream and downstream region respectively, stenosis index generating unit generating a stenosis index indicating the degree of stenosis in the first blood vessel based on the stenosis upstream and downstream curve, and display unit displaying the stenosis index.

US Patent:

20140086461, Mar 27, 2014

Filed:

Sep 25, 2012

Appl. No.:

13/626623

Inventors:

- OTAWARA-SHI, JP
- BALTIMORE MD, US
Jeff TROST - BALTIMORE MD, US
Richard T. GEORGE - BALTIMORE MD, US
Joao A.C. LIMA - BALTIMORE MD, US
Omair YOUSUF - BALTIMORE MD, US

Assignee:

THE JOHNS HOPKINS UNIVERSITY - BALTIMORE MD
TOSHIBA MEDICAL SYSTEMS CORPORATION - OTAWARA-SHI

International Classification:

G06K 9/46

US Classification:

382128

Abstract:

A predetermined time-based index ratio such as time-based fractional flow reserve (FFR) is determined for evaluating a level of blood circulation between at least two locations such as a proximal location and a distal location in a selected blood vessel in the region of interest. One time-based FFR is obtained by normalizing a risk artery ratio by a reference artery ratio.