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Robert H. Edwards - San Francisco CA Richard J. Reimer - San Francisco CA Steven L. McIntire - Tiburon CA Erik M. Jorgensen - Salt Lake City UT Kim Schuske - Salt Lake City UT
Assignee:
The Regents of the University of CA - Oakland CA University of Utah Research Foundation - Salt Lake City UT
Disclosed are invertebrate and vertebrate synaptic vesicle amino acid transporter compositions which define a novel family of transporter proteins, recombinant vectors and cells comprising nucleic acid sequences encoding vertebrate synaptic vesicle amino acid transporter proteins and antibodies directed against such proteins. Also disclosed are methods for utilizing such compositions in screening assays and treatment regimens.
Robert H. Edwards - San Francisco CA Elizabeth E. Bellocchio - Walnut Creek CA Richard J. Reimer - San Francisco CA
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C12Q 100
US Classification:
435 4, 435 6, 435 71, 435 72, 435 721, 435325
Abstract:
This invention pertains to the identification of a novel class of glutamate transporters. In particular, this invention pertains to the discovery that proteins originally considered to perform an entirely different function (BNPI, DNPI, etc. ), in fact, transport glutamate into synaptic vesicles. Designated VGLUT glutamate transporters, the transporters provide good targets with which to screen for modulators of glutamate uptake into synaptic vesicles.
Medicine Doctors
Dr. Richard J Reimer, Stanford CA - MD (Doctor of Medicine)
300 Pasteur Dr Suite A301, Stanford, CA 94305 6507237093 (Phone)
Certifications:
Neurology, 1998
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
300 Pasteur Dr Suite A301, Stanford, CA 94305
Stanford Hospital and Clinics 300 Pasteur Drive, Stanford, CA 94305
Education:
Medical School Emory University School Of Medicine Graduated: 1991 Medical School Ucsf Medical Center Graduated: 1991 Medical School University Ca Sf School Of Med Graduated: 1991
Dr. Reimer graduated from the SUNY Downstate Medical Center College of Medicine in 1981. He works in Dartmouth, MA and specializes in Internal Medicine. Dr. Reimer is affiliated with St Lukes Hospital.
Dr. Reimer graduated from the Emory University School of Medicine in 1991. He works in Palo Alto, CA and specializes in Neurology. Dr. Reimer is affiliated with Stanford Hospital.
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Youtube
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