Richard S Rubenstein

US Patent:

7847941, Dec 7, 2010

Filed:

Dec 5, 2006

Appl. No.:

11/634546

Inventors:

Richard Rubenstein - Staten Island NY, US
Martin Piltch - Los Alamos NM, US
Perry Gray - Los Alamos NM, US

Assignee:

Los Alamos National Security, LLC - Los Alamos NM

International Classification:

G01N 21/25

US Classification:

356417

Abstract:

A system for analyzing a sample for the presence of an analyte in a sample. The system includes a sample holder for containing the sample; an excitation source, such as a laser, and at least one linear array radially disposed about the sample holder. Radiation from the excitation source is directed to the sample, and the radiation induces fluorescent light in the sample. Each linear array includes a plurality of fused silica optical fibers that receive the fluorescent light and transmits a fluorescent light signal from the first end to an optical end port of the linear array. An end port assembly having a photo-detector is optically coupled to the optical end port. The photo-detector detects the fluorescent light signal and converts the fluorescent light signal into an electrical signal.

US Patent:

20100261195, Oct 14, 2010

Filed:

Mar 25, 2010

Appl. No.:

12/731776

Inventors:

Richard Rubenstein - Staten Island NY, US
Martin S. Piltch - Los Alamos NM, US
Perry Clayton Gray - Los Alamos NM, US

International Classification:

G01N 33/53
G01N 33/50
C07K 16/00
G01N 23/00

US Classification:

435 71, 436 86, 436501, 5303881, 436 63, 436 57

Abstract:

Methods for detection of the presence or absence of PrPin a biological sample suspected of having them comprising the steps of concentrating the PrPas may be present in the sample by substantially separating the PrPfrom the sample matrix; labeling the concentrated PrPwith at least one molecular label to produce labeled PrP; and detecting the labeled PrPon an instrument capable of detecting an attomole quantity of labeled PrP, and wherein the duration of time between concentrating the PrPand analyzing the labeled PrPis about 48 hours or less.

US Patent:

48066273, Feb 21, 1989

Filed:

May 29, 1987

Appl. No.:

7/055708

Inventors:

Henryk M. Wisniewski - Staten Island NY
Richard J. Kascsak - Middletown NJ
Richard Rubenstein - Staten Island NY
Patricia A. Merz - Staten Island NY

Assignee:

Research Foundation of Mental Hygiene Inc. - Albany NY

International Classification:

A61K 39395
C07K 1514

US Classification:

530387

Abstract:

Hybridoma tumor cell line ATCC No. HB9222. A monoclonal antibody, specific for scrapie-associated fibrils and the proteins which comprise scrapie-associated fibrils, produced by said cell line.

US Patent:

20160091503, Mar 31, 2016

Filed:

Sep 30, 2015

Appl. No.:

14/871232

Inventors:

- Albany NY, US
Richard Rubenstein - Staten Island NY, US

International Classification:

G01N 33/68
G01N 33/58

Abstract:

Compositions and methods for accurate and sensitive quantitation of T-tau and P-tau are disclosed.

Address:

39 Midlands Dr, West Hartford, CT 06107

Phone:

8605613828

VIN:

WAUFGAFC5CN071499

Make:

AUDI

Model:

A6

Year:

2012

Address:

39 Midlands Dr, West Hartford, CT 06107

Phone:

8605613828

VIN:

WAUDH74F58N150439

Make:

AUDI

Model:

A6

Year:

2008