Richard E Saunders

US Patent:

6352718, Mar 5, 2002

Filed:

Sep 25, 2000

Appl. No.:

09/668883

Inventors:

Joseph K. Yoon - Palisade Park NJ
Richard W. Saunders - Palisades NY
Mahdi Fawzi - Morristown NJ

Assignee:

American Cyanamid Company - Madison NJ

International Classification:

A61K 964

US Classification:

424456, 424484, 424486, 514220, 514561, 514562, 514563, 514564

Abstract:

This invention provides novel formulations for N-[4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)ylcarbonyl)-3-chlorophenyl]-5-fluoro-2-methyl-benzamide, or a pharmaceutically acceptable salt thereof, and processes for making them, the formulations comprising from about 1% to about 20% of active ingredient, from about 1% to about 18% of a surfactant component, from about 50% to about 80% of a component of one or more polyethylene glycols, from about 1% to about 20% of a component of one or more sucrose fatty acid esters and/or polyvinylpyrrolidone and, optionally, one or more pharmaceutically acceptable preservatives or antioxidants.

US Patent:

6437006, Aug 20, 2002

Filed:

Sep 25, 2000

Appl. No.:

09/668970

Inventors:

Joseph K. Yoon - Palisade Park NJ
Richard W. Saunders - Palisades NY
Mahdi Fawzi - Morristown NJ

Assignee:

American Cyanamid Company - Madison WI

International Classification:

A61K 4732

US Classification:

5147725, 514966, 424464, 424474, 424480, 424485

Abstract:

This invention provides carrier systems useful in preparing pharmaceutical formulations, the systems comprising, by weight percentage, from about 1% to about 20%, preferably from about 5% to about 12%, of a surfactant component; from about 55% to about 93%, preferably from about 60% to about 85%, of a component of one or more polyethylene glycols (PEG); and from about 1% to about 25%, preferably from about 5% to about 15%, of one or more sucrose fatty acid esters or polyvinylpyrrolidone (PVP) with a K value between about 15 and about 90, preferably with a K value of from about 16 to about 18, most preferably about 17, as defined in USP/NF, or a combination of one or more sucrose fatty acid esters or PVP, and, optionally, one or more pharmaceutically acceptable preservatives or antioxidants, such as BHA, BHT, ascorbyl palmitate or benzyl alcohol.

US Patent:

6831079, Dec 14, 2004

Filed:

Sep 25, 2000

Appl. No.:

09/669204

Inventors:

Joseph K. Yoon - Palisade Park NJ
Richard W Saunders - Palisades NY
Mahdi Fawzi - Morristown NJ

Assignee:

American Cyanamid Company - Madison NJ

International Classification:

A61K 3155

US Classification:

514220, 514937, 424452, 424455

Abstract:

This invention provides novel formulations for vasopressin agonist compounds, or a pharmaceutically acceptable salt thereof, having the general structure: and processes for making them, the formulations comprising from about 1% to about 20% of active ingredient, from about 1% to about 18% of a surfactant component, from about 50% to about 80% of a component of one or more polyethylene glycols, from about 1% to about 20% of a component of one or more sucrose fatty acid esters and/or polyvinylpyrrolidone and, optionally, one or more preservatives or antioxidants.

US Patent:

7544370, Jun 9, 2009

Filed:

Sep 30, 2004

Appl. No.:

10/955567

Inventors:

Sripriya Venkata Ramana Rao - Iselin NJ, US
Syed M. Shah - East Hanover NJ, US
Hanumantharao Tatapudy - Suffern NJ, US
Richard William Saunders - Palisades NY, US
Mahdi Fawzi - Morristown NJ, US
Arwinder Nagi - Thiells NY, US
Shailesh Singh - Bardonia NY, US
Sumon A. Hasan - Monroe NY, US

Assignee:

Wyeth - Madison NJ

International Classification:

A61K 9/64

US Classification:

424456

Abstract:

Pantoprazole sodium multiparticulates are described which avoid sticking to nasogastric and gastronomy tubes. The pantoprazole multiparticulates have a spheroid core of pantoprazole or an enantiomer thereof, or a salt thereof, a surfactant, and a distintegrant; a sub coat which is comprised of hydroxypropyl methylcellulose (hypromellose) and water, an enteric coat on the sub-coat, and a final seal coat over the enteric coat, which is composed of hydroxypropyl methylcellulose (hypromellose) and water.

US Patent:

7838027, Nov 23, 2010

Filed:

Sep 30, 2004

Appl. No.:

10/574210

Inventors:

Sripriya Venkata Ramana Rao - Iselin NJ, US
Syed M. Shah - East Hanover NJ, US
Hanumantharao Tatapudy - Suffern NY, US
Richard William Saunders - Palisades NY, US
Mahdi Fawzi - Morristown NJ, US
Arwinder Nagi - Thiells NY, US
Shailesh Singh - Bardonia NY, US
Sumon A. Hasan - Monroe NY, US

Assignee:

Wyeth LLC - Madison NJ

International Classification:

A61K 9/64

US Classification:

424456

Abstract:

Pantoprazole sodium multiparticulates are described which avoid sticking to nasogastric and gastronomy tubes. The pantoprazole multiparticulates have a spheroid core of pantoprazole or an enantiomer thereof, or a salt thereof, a surfactant, and a disintegrant; a sub coat which is comprised of hydroxypropyl methylcellulose (hypromellose) and water, an enteric coat on the sub-coat, and a final seal coat over the enteric coat, which is composed of hydroxypropyl methylcellulose (hypromellose) and water.

US Patent:

20070015828, Jan 18, 2007

Filed:

Jul 13, 2006

Appl. No.:

11/485663

Inventors:

Syed Shah - East Hanover NJ, US
Eric Ehrnsperger - Chestnut Ridge NY, US
Richard Saunders - Palisades NY, US
Mahdi Fawzi - Morristown NJ, US
Rocco Galante - Oakland NJ, US
Garth Whiteside - West Windsor NJ, US

Assignee:

Wyeth - Madison NJ

International Classification:

A61K 31/277
A61K 31/137

US Classification:

514522000, 514649000, 558418000, 564338000

Abstract:

Highly selective dual serotonin and norepinephrine reuptake inhibitors are provided. These compounds have a lower side-effect profile and are useful in compositions and products for use in treatment of a variety of conditions including depression, fibromyalgia, anxiety, panic disorder, agorophobia, post traumatic stress disorder, premenstrual dysphoric disorder, attention deficit disorder, obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, autism, schizophrenia, obesity, anorexia nervosa, bulimia nervosa, Gilles de la Tourette Syndrome, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction, borderline personality disorder, fibromyalgia syndrome, diabetic neuropathic pain, chronic fatigue syndrome, pain, visceral pain, Shy Drager syndrome, Raynaud's syndrome, Parkinson's Disease, and epilepsy.